Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…Significant differences were also found between responders and non-responders in the first-order radiomic feature Energy.…”

Image2_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.png by Mingming Hou (11341656)

“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”

Table 2_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.xlsx by Lianjie Ruan (22660265)

“…To evaluate its therapeutic potential, we administered exogenous carnosine in both models and assessed its effects on body weight, inflammatory cytokine expression, and histopathological changes.</p>Results<p>Carnosine supplementation significantly improved body weight maintenance, reduced the expression of pro-inflammatory cytokines, and attenuated histological lung damage in both LPS- and papain-induced lung injury models. …”

Image1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.PDF by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf by Renfeng Li (126284)

“…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …”

Supplementary file 1_Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors.zip... by Ramin Karimianghadim (21288299)

“…No significant increase in clinically important ARGs was detected.…”

Table1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.DOCX by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Table1_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx by Mingming Hou (11341656)

“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”

Image 1_High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota.tif by Yu Xia (8822)

“…Furthermore, oral administration of high-dose thiamine also regulated HFFD-induced gut microbiota dysbiosis by reshaping its structure and composition of gut microbiota, such as increasing the relative abundance of Actinobacteria and Bifidobacterium pseudolongum, and reducing the relative abundance of Proteobacteria and Ruminococcus gnavus, accompanied by decreased level of gut-derived endotoxin. Finally, significant correlations were found between obesity-related phenotypes and gut microbiota through correlation analysis.…”

Table 1_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx by Wenjing Chang (8334480)

Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Data Sheet 1_Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV.docx by Sierra P. Feeney (21466928)

“…<p>The dysregulation of sleep–wake patterns that occurs during aging is well documented and coincides with changes in intracellular signaling pathways that regulate sleep, such as the calcium/calmodulin-dependent protein kinase (CaMKII)/cyclic-AMP response element-binding protein (CREB) pathway. …”

Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Table3_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx by Mingming Hou (11341656)

“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”

Table 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Table 1_In vivo profiling of the PE/PPE proteins of Mycobacterium tuberculosis reveals diverse contributions to virulence.xlsx by Benjamin Koleske (11581641)

“…We found consistent, time-dependent changes in mutant abundance across our animal replicates and identified decreases in several key mutant strains known to promote bacterial growth or virulence. …”

Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip by Zixu Wang (6297470)

“…The study investigated the oxidative damage in TM3 cells induced by H₂O₂ and demonstrated that salidroside significantly decreased the levels of ROS and MDA, while increasing the levels of testosterone, SOD, GSH. …”

Data Sheet 1_Left ventricular hypertrophy and myocardial work in amateur marathon runners.pdf by Juncheng Wang (4047784)

“…</p>Results<p>Compared with the control group, both the non-LVH and LVH groups exhibited significant enlargement of the left atrium and left ventricle (LV), increased wall thickness, and elevated LV mass, with the LVH group showing more pronounced changes. …”

Image 9_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Image 3_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”