Causal impacts of 731 immunocyte phenotypes on colorectal cancer-evidence from a bidirectional two-sample Mendelian randomization by Xinyue Gu (7335398)

“…The bidirectional two-sample Mendelian randomization analysis was performed to explore the association between 731 types of immune cell phenotypes-specific changes and colorectal cancer. The inverse variance weighting results indicated that a total of 31 and 28 immune cell phenotypes significantly associated with colorectal cancer in two different datasets, respectively. …”

Data Sheet 1_The role of intestinal homeostasis in sevoflurane-induced myelin development and cognitive impairment in neonatal mice.docx by Chang Liu (35901)

“…In the hippocampus and prefrontal cortex, the expression of genes and transcription factors related to oligodendrocyte differentiation and myelin development was significantly affected, and these changes persisted even after the exposure ended. …”

Image 1_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…Furthermore, hexosylceramides (HexCers) and ceramides (Cers) in the AD model’s hippocampus, the prominent sphingolipids in the hippocampus of AD mice, existed as the two primary changed lipid metabolites. The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). …”

Image 2_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…Furthermore, hexosylceramides (HexCers) and ceramides (Cers) in the AD model’s hippocampus, the prominent sphingolipids in the hippocampus of AD mice, existed as the two primary changed lipid metabolites. The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). …”

PRMT5 regulates alternative splicing landscape under hypoxia. by Srinivas Abhishek Mutnuru (22513457)

“…<p><b>A)</b> Pie chart showing distribution of different types of significant AS events (FDR < 0.05) in shCTRL vs. shPRMT5 MDA-MB-231 cells under hypoxia. …”

Supplementary Material for: Global, Regional, and National Burden of Neonatal Encephalopathy Due to Birth Asphyxia and Trauma, Its Attributable Risk Factors, 1990-2021: Results fro... by figshare admin karger (2628495)

“…Low SDI regions experienced a substantial 112.9% increase in NEBAT cases, while high-middle SDI regions witnessed a significant 34.8% decrease. Although mortality rates declined across all SDI regions, the low SDI region had the smallest decline. …”

Supplementary file 1_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... by Nian Jiang (1338381)

“…Lowering the METS-IR index below 38.1 through lifestyle changes and diet control can significantly reduce the risk of cognitive impairment and may decrease the incidence of dementia.…”

Data_Sheet_1_The total joint arthroplasty care patterns in China during the COVID-19 pandemic: a multicenter cohort study.PDF by Tianyi Zhang (87298)

“…No significant changes were observed in the proportion of hospitalizations for TJA. …”

Image 1_Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice.pdf by Yan Gong (103494)

“…Additionally, MA notably inhibited osteoclast activity, as evidenced by a decrease in the number of osteoclasts and a significant suppression of F-actin formation. …”

Supplementary file 1_Comparison of the ruminal microbiome responses of temperate and tropically adapted beef steers to dietary supplementation with monensin.docx by Ross L. Thorn (22688840)

“…SCFA analysis showed a decrease in the acetate/propionate ratio (p = 0.001) across all breed types under monensin treatment. …”

DataSheet1_Clerodendranthus spicatus [Orthosiphon aristatus (Blume) Miq.] maintains uric acid homeostasis via regulating gut microbiota and restrains renal inflammation in hyperuri... by Yang Wang (5921)

“…</p>Results<p>In HN mice, C. spicatus could significantly reduce serum uric acid levels and improve renal function. …”

Supplementary file 2_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... by Nian Jiang (1338381)

“…Lowering the METS-IR index below 38.1 through lifestyle changes and diet control can significantly reduce the risk of cognitive impairment and may decrease the incidence of dementia.…”

Treatment with TCA and S1P2 agonist induces S1PR2 expression and attenuates ROCK1/RHOA expression; inhibition of S1PR2 reverses TCA- or S1P2-mediated effect on ROCK1/RHOA expressio... by Aya Miyagawa-Hayashino (386487)

“…TCA- or S1P2-mediated S1PR2 expression was suppressed following pretreatment with JTE-013. The changes in protein levels of RhoA and ROCK1 were not significant. …”

Video1_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study.m... by Juhina Das (17808068)

“…Therapeutic NLGP treatment delayed pre-neoplastic changes promoting normalization of mucosa by maintaining normal structure. …”

DataSheet2_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical stu... by Juhina Das (17808068)

“…Therapeutic NLGP treatment delayed pre-neoplastic changes promoting normalization of mucosa by maintaining normal structure. …”

DataSheet1_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical stu... by Juhina Das (17808068)

“…Therapeutic NLGP treatment delayed pre-neoplastic changes promoting normalization of mucosa by maintaining normal structure. …”

Table 1_Temporal trends of cervical cancer demographics: a CDC WONDER database study.docx by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. …”

Image 4_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. …”

Image 2_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. …”

Image 3_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. …”