Supplementary file 2_Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.docx حسب Ziao Liu (8938748)

"…Mechanistic investigations revealed that WZYZW markedly suppressed germ cell apoptosis (flow cytometry confirmed a significant decrease in apoptotic cell proportion) and attenuated DNA damage (indicated by significantly reduced γ-H2AX (a DNA damage marker) fluorescence intensity). …"

The ADMET analysis of the selected compounds. حسب Ali Alisaac (14658440)

"…Rg values confirmed this, with the LasI-Sulfamerazine complex being more compact (~2.00 nm) than QscR-ligand complexes (2.10–2.30 nm). PCA revealed significant conformational changes in the LasI-Sulfamerazine complex, with PC1 explaining 57.26% variance. …"

AMDET profiling parameters and shorting criteria. حسب Ali Alisaac (14658440)

"…Rg values confirmed this, with the LasI-Sulfamerazine complex being more compact (~2.00 nm) than QscR-ligand complexes (2.10–2.30 nm). PCA revealed significant conformational changes in the LasI-Sulfamerazine complex, with PC1 explaining 57.26% variance. …"

Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG حسب Johnny Amer (495285)

"…D- and L-Glu supplementations showed significant decrease of Glycogenesis (low GYS2/PYGL ratio) and unchanged p-AKT pattern compared to their RD counterparts.…"

Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG حسب Johnny Amer (495285)

"…D- and L-Glu supplementations showed significant decrease of Glycogenesis (low GYS2/PYGL ratio) and unchanged p-AKT pattern compared to their RD counterparts.…"

Assessment of calcium events, pERK levels, NMDA receptor expression and extracellular zinc levels in <i>slc13a5</i> mutants. حسب Deepika Dogra (21072023)

"…(D) Whole-brain activity MAP-map depicting significant changes in pERK signal, calculated using Mann-Whitney U statistic Z score. …"

Data Sheet 1_Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.pdf حسب Louis Schreel (22385035)

"…While some studies have shown no significant change in cholesterol levels, and some have shown improvements, still others have highlighted the potential of KDs to induce or exacerbate hyperlipidemia.…"

Table1_Cognitive performance in ISS astronauts on 6-month low earth orbit missions.docx حسب Sheena I. Dev (20293434)

"…There was slowed performance observed in early flight on tasks of processing speed, visual working memory, and sustained attention. We observed a decrease in risk-taking propensity during late flight and post-flight mission phases. …"

Image1_Cognitive performance in ISS astronauts on 6-month low earth orbit missions.pdf حسب Sheena I. Dev (20293434)

"…There was slowed performance observed in early flight on tasks of processing speed, visual working memory, and sustained attention. We observed a decrease in risk-taking propensity during late flight and post-flight mission phases. …"

Ketamine wash-in. حسب Anne S. Fleiner (20496284)

"…(ii) The change in post-burst spiking after the wash-in of 20 μM and 100 μM was not significant compared to the control (MWU test). …"

Table 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.xlsx حسب Yu Xia (8822)

"…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …"

Image 3_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... حسب Ning Ding (456674)

"…These changes were reversed by MA and probiotics.</p>Conclusion<p>MA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. …"

Image 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... حسب Ning Ding (456674)

"…These changes were reversed by MA and probiotics.</p>Conclusion<p>MA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. …"

Image 4_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... حسب Ning Ding (456674)

"…These changes were reversed by MA and probiotics.</p>Conclusion<p>MA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. …"

Table 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... حسب Ning Ding (456674)

"…These changes were reversed by MA and probiotics.</p>Conclusion<p>MA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. …"

Image 2_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... حسب Ning Ding (456674)

"…These changes were reversed by MA and probiotics.</p>Conclusion<p>MA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. …"

Data Sheet 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.pdf حسب Yu Xia (8822)

"…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …"

Experimental procedure flow. حسب Yanxu Liang (22227024)

"…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…"

Aperture parameters. حسب Yanxu Liang (22227024)

"…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…"

Image details. حسب Yanxu Liang (22227024)

"…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…"