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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
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5221
Table_1_Effectiveness of Korean medicine treatments in improving cognitive function and prefrontal cortex activity in older individuals with mild cognitive impairment: retrospectiv...
Published 2024“…Additionally, the deoxygenated hemoglobin beta coefficient in the left frontopolar prefrontal cortex significantly decreased during the Stroop task after the intervention.…”
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5222
Table 4_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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5223
Data Sheet 4_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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5224
Image 2_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif
Published 2025“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
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5225
Data Sheet 1_Red mite (Panonychus citri) attack amplifies citrus rootstock-driven responses in physiological and biochemical traits, VOC emission, and expression of defence-related...
Published 2025“…<p>Citriculture faces significant constraints in expanding into new environments and agroecological zones. …”
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5226
Image 3_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff
Published 2024“…</p>Conclusion<p>Hemodynamic changes during exercise in CCS patients were effectively evaluated using ESE. …”
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5227
Image 4_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”
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5228
Table 1_Safety and efficacy of canine recombinant IL-15 in mammary gland tumors.docx
Published 2025“…Clinical monitoring included physiological assessments, blood tests, and owner-reported quality of life (QoL) questionnaires. No significant adverse changes were observed in hematological, biochemical, or physiological parameters. …”
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5229
Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur...
Published 2025“…Age-standardized rates (ASRs) were calculated, and trends were assessed using the Estimated Annual Percentage Change (EAPC) measure. Decomposition analysis quantified the contributions of population growth, aging, and epidemiological changes. …”
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5230
Table 1_Longitudinal relationships between daily activities, depressive symptoms, anxiety, and suicidality during the COVID-19 pandemic: a three-wave cross-lagged study.docx
Published 2025“…Background<p>The COVID-19 pandemic has caused significant unprecedented changes in lives. In particular, core daily activities, such as sleep, diet, physical activity, education, and social activities have significantly changed. …”
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5231
Table 1_Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission.xlsx
Published 2025“…For instance, Leptin and Insulin levels decreased, particularly in Breast cancer patients, whereas Colorectal cancer patients exhibited a reduction in pro-inflammatory cytokines such as IL-1β, IL-6, IL-8, and TNF-α, even in the absence of weight loss and bioimpedential feature changes. …”
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5232
Table 1_Xianyu capsule ameliorates neuroinflammatory and glycerophospholipid metabolism in lithium-pilocarpine-induced acute epilepsy.docx
Published 2025“…</p>Results<p>XYC administration ameliorated the pathological changes and neurons apoptosis of brain hippocampus CA1 region, with reduced MDA and increased SOD and CAT levels in hippocampus, and decreased inflammation cytokine in serum. 16S rDNA sequencing revealed distinct gut microbial restructuring in XYC-treated epileptic models, characterized by phylum-level alterations in lipid-associated taxa (Tenericutes, Patescibacteria, Epsilonbacteraeota, Proteobacteria) and genus-level modulations (Lactobacillus, Ramboutsia, Staphylococcus). …”
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5233
Table 1_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.docx
Published 2024“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”
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5234
Data Sheet 6_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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5235
Image 3_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”
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5236
<b>Differential Effects of Retinol-Binding Protein 3 and Anti-VEGF Antibodies on Retinal Dysfunctions in Diabetic Retinopathy</b>
Published 2025“…<p dir="ltr">Anti-vascular endothelial growth factor (anti-VEGF) therapies are effective treatment of severe diabetic retinopathy (DR) and macular edema, but a significant subset of people showed inadequate response to anti-VEGF intervention. …”
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5237
Data_Sheet_1_Effects of stand age and soil microbial communities on soil respiration throughout the growth cycle of poplar plantations in northeastern China.pdf
Published 2024“…Bacterial and fungal communities differed significantly in abundance, composition, and function, with the Litter C/N ratio being a key variable affected by microbial community changes.…”
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5238
Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx
Published 2025“…Introduction<p>The Guangxi Zhuang Autonomous Region of China is home to numerous Ficus altissima Blume (F. altissima) ancient trees over 300 years old, which hold significant cultural, ecological, and scientific research value. …”
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5239
Table 3_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx
Published 2024“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”
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5240
Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff
Published 2025“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”