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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
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5421
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5422
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5423
Table 1_Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels of Clausena lansium L. Skeels.docx
Published 2025“…Despite the significant increase of FLS expression in PP, the contents of kaempferol, quercetin, and myricetin significantly decreased, suggesting that the increase of FLS expression did not lead to an increase in flavonol biosynthesis.…”
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5424
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5425
Temporal Regulation of Myopia and Inflammation-Associated Pathways in the Interphotoreceptor Retinoid-Binding Protein Knockout Mouse Model
Published 2024“…</p> <p>The ddPCR data analysis indicated that numerous myopia and inflammation-associated genes were differentially regulated in IRBP KO retinas with distinct temporal variation (upregulated at P5, decreased at P40, and no change at P213 relative to WT). …”
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5426
Data Sheet 1_Effects of drospirenone and ethinylestradiol tablets (II) combined with metformin on the composition of gut microbiota in polycystic ovary syndrome with insulin resist...
Published 2025“…After treatment, CHO levels decreased in PCOS-NIR group (P < 0.05); FINS, LDL-C and HOMA-IR decreased and HDL-C levels increased in PCOS-IR group (P < 0.05). 2. …”
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5427
Loss of H2A.Z from transcription start sites was correlated with, but not required for, HU-induced gene activation.
Published 2025“…The p-values, generated using hypergeometric probability, indicate if the overlap in each group was significantly greater (red) or less (blue) than excepted by chance (black = non-significant). …”
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5428
Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx
Published 2025“…Estimated annual percentage changes in the age-standardized DALYs rate (ASDR) of stroke, by age, sex, socio-demographic index (SDI), and subtype, were calculated to quantify the temporal trends.…”
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5429
Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf
Published 2025“…Mice subjected to middle cerebral artery occlusion (MCAO) exhibited significant reductions in infarct size and brain edema, prolonged post-MCAO survival, and improved behavioral outcomes following aCD19 Ab treatment. …”
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5430
Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …”
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5431
Image 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …”
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5432
Figure 3 from Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRP...
Published 2025“…Percentage of fragmented mitochondria on the <i>y</i>-axis represents the comparison between control and Acetalax-treated groups. <b>A,</b> Significant change in mitochondrial fragmentation is indicated by the brackets. *, <i>P</i> < 0.01; **, <i>P</i> < 0.005; ***, <i>P</i> < 0.0001 (using the Mann–Whitney <i>U</i> test, calculated in Prism 9.0). …”
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5433
Table 2_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx
Published 2025“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”
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5434
Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx
Published 2025“…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …”
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5435
Data Sheet 1_From court to community: a cost–benefit evaluation of a community sports programme for Arab women in Israel's multiethnic context.docx
Published 2025“…The non-randomized design examined within-participant changes over a 10-month period, providing real-world evidence of programme effectiveness. …”
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5436
Table 1_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx
Published 2025“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”
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5437
Data Sheet 1_CARTOON-based educational intervention for children to foster hygiene knowledge and emotional resilience in preschool children: a randomized controlled trial.pdf
Published 2025“…Additionally, anxiety scores significantly decreased in the intervention group post-intervention compared to baseline (2.2 ± 1.7 vs. 5.6 ± 2.5; p = .01). …”
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5438
Image 4_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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5439
Table 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …”
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5440
Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif
Published 2025“…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …”