Differential mRNA expression of key metabolic and stress response genes in the <i>MYH7</i> Q315R mice. by Shinya Takarada (8655066)

“…Clustering maps show significant changes in RNA expression (p < 0.05) greater than twofold or less than −2.0-fold (A and C). …”

The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... by Mohammed A. Altowijri (22461945)

“…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …”

Supplementary file 5_Exploration of the role and mechanism of Rhizoma Paridis total saponins in osteosarcoma based on SPI1/LCN2-mediated ferroptosis.zip by Ge Yang (169466)

“…Background<p>Osteosarcoma (OS) is a highly aggressive bone malignancy with limited therapeutic options and poor prognosis, particularly in cases of recurrence or metastasis. Recent studies have identified ferroptosis as a promising therapeutic target in OS, with the SPI1/LCN2 regulatory axis emerging as a critical modulator of this process. …”

Novel Compound Heterozygous Variants of the <i>PLD1</i> Gene in a Fetus with Congenital heart disease by Linyan Zhu (19930716)

“…To date, more than 400 genes have been linked to CHD, the genetic analysis of CHD cases is crucial for both clinical management and etiological determination. …”

Supplementary file 2_Pharmacist-led remote follow-up service for non-metastatic breast cancer patients: a prospective randomised controlled trial of pharmaceutical intervention.jpe... by Miaohui Wu (19759434)

“…Background<p>Non-metastatic breast cancer accounts for 87.8% of breast cancer cases. However, the high risk of drug adverse drug reactions due to multiple combined medications, along with the urgent need for out-of-hospital medication adherence and management, poses substantial challenges. …”

Supplementary file 3_Pharmacist-led remote follow-up service for non-metastatic breast cancer patients: a prospective randomised controlled trial of pharmaceutical intervention.doc... by Miaohui Wu (19759434)

“…Background<p>Non-metastatic breast cancer accounts for 87.8% of breast cancer cases. However, the high risk of drug adverse drug reactions due to multiple combined medications, along with the urgent need for out-of-hospital medication adherence and management, poses substantial challenges. …”

Supplementary file 4_Exploration of the role and mechanism of Rhizoma Paridis total saponins in osteosarcoma based on SPI1/LCN2-mediated ferroptosis.zip by Ge Yang (169466)

“…Background<p>Osteosarcoma (OS) is a highly aggressive bone malignancy with limited therapeutic options and poor prognosis, particularly in cases of recurrence or metastasis. Recent studies have identified ferroptosis as a promising therapeutic target in OS, with the SPI1/LCN2 regulatory axis emerging as a critical modulator of this process. …”

Supplementary file 1_Serum titin/creatinine ratio as a biomarker for discriminating disease severity in Duchenne and Becker muscular dystrophies.docx by Yoshinori Nambu (17736762)

“…Patients were classified by the reading frame rule (out-of-frame, DMD; in-frame, BMD). Exceptional cases in which in-frame variants presented with severe symptoms or out-of-frame variants presented with mild symptoms were considered clinically DMD or clinically BMD, respectively. …”

Supplementary file 2_Exploration of the role and mechanism of Rhizoma Paridis total saponins in osteosarcoma based on SPI1/LCN2-mediated ferroptosis.zip by Ge Yang (169466)

“…Background<p>Osteosarcoma (OS) is a highly aggressive bone malignancy with limited therapeutic options and poor prognosis, particularly in cases of recurrence or metastasis. Recent studies have identified ferroptosis as a promising therapeutic target in OS, with the SPI1/LCN2 regulatory axis emerging as a critical modulator of this process. …”

The trajectory of serum salicylate concentrations after ingestion of medicinal oil containing methyl salicylate by Rex Pui Kin Lam (14013625)

“…Multivariable generalized linear regression was used to identify factors significantly associated with the peak serum concentration and the time from ingestion to peak concentration.…”

Supplementary file 1_Pharmacist-led remote follow-up service for non-metastatic breast cancer patients: a prospective randomised controlled trial of pharmaceutical intervention.jpe... by Miaohui Wu (19759434)

“…Background<p>Non-metastatic breast cancer accounts for 87.8% of breast cancer cases. However, the high risk of drug adverse drug reactions due to multiple combined medications, along with the urgent need for out-of-hospital medication adherence and management, poses substantial challenges. …”

Supplementary file 1_Exploration of the role and mechanism of Rhizoma Paridis total saponins in osteosarcoma based on SPI1/LCN2-mediated ferroptosis.zip by Ge Yang (169466)

“…Background<p>Osteosarcoma (OS) is a highly aggressive bone malignancy with limited therapeutic options and poor prognosis, particularly in cases of recurrence or metastasis. Recent studies have identified ferroptosis as a promising therapeutic target in OS, with the SPI1/LCN2 regulatory axis emerging as a critical modulator of this process. …”

Supplementary file 3_Exploration of the role and mechanism of Rhizoma Paridis total saponins in osteosarcoma based on SPI1/LCN2-mediated ferroptosis.zip by Ge Yang (169466)

“…Background<p>Osteosarcoma (OS) is a highly aggressive bone malignancy with limited therapeutic options and poor prognosis, particularly in cases of recurrence or metastasis. Recent studies have identified ferroptosis as a promising therapeutic target in OS, with the SPI1/LCN2 regulatory axis emerging as a critical modulator of this process. …”

Characteristic TARC/CCL17 expression in the salivary gland of IgG4-related disease: potential diagnostic utility and insights into pathogenesis by Nanako Kikuchi (20670002)

“…Immunohistochemical analysis revealed TARC/CCL17 positivity in 87.2% of histologically confirmed IgG4-RD cases and negativity in 84.6% of histologically unconfirmed but clinically suspected IgG4-RD cases. …”

Supplementary file 1_Association between chronic diseases and lifestyle risk factors among community-dwelling older adults: a retrospective cross-sectional Chinese population-based... by Wei Xin (306299)

“…</p>Results<p>There were 361 cases [mean age 74.65 (SD = 5.61) years] included in the sample (from total registry records n = 6,351). …”

Table2_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.xlsx by Friederike Behler-Janbeck (3384488)

“…MicroCT scanning of femoral bones of Gpr41/43 dKO mice revealed a significant increase of trabecular bone volume and trabecular compared to WT controls. …”

Supplementary file 1_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.docx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Image 2_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Image 2_NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.tiff by M. Firoz Mian (10013314)

“…However, DMPA significantly decreased the total number of VT CD4+ and CD8+ T cells and the number of IFN-γ producing CD4 and CD8 T cells and increased the percentage of CD4 and CD8 T cells producing TNF-α compared to untreated mice. …”

Image 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”