Baseline demographic characteristics. حسب Jung-Tae Kim (8997767)

الموضوعات:

This file contains the complete dataset analyzed in the current study, including all variables used for statistical modeling. حسب Jung-Tae Kim (8997767)

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Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms حسب Farman M. Abbasi (22318766)

"…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…"

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms حسب Farman M. Abbasi (22318766)

"…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…"

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms حسب Farman M. Abbasi (22318766)

"…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…"

Baseline Characteristics of Study Participants. حسب Swati M. Surkar (8399427)

"…The results demonstrate that DT training significantly improves and retains DT performance, likely due to a reduction in cognitive-motor interference. …"

Raw and processed data files. حسب Swati M. Surkar (8399427)

"…The results demonstrate that DT training significantly improves and retains DT performance, likely due to a reduction in cognitive-motor interference. …"

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation حسب Kaiqing Sun (18715965)

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Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation حسب Kaiqing Sun (18715965)

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Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation حسب Kaiqing Sun (18715965)

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Busulfan treatment induces orchitis. حسب Lingjun Zhao (21763122)

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Effects of busulfan treatment (6 mg/kg) on the body and testes weights of mice over three weeks. حسب Lingjun Zhao (21763122)

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Effect of busulfan treatment on androgens and androgen receptors. حسب Lingjun Zhao (21763122)

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Effects of busulfan treatment (6 mg/kg) on the epididymis and sperm of mice over a three-week period. حسب Lingjun Zhao (21763122)

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Effect of busulfan treatment on vimentin, a supporting cytoskeletal protein. حسب Lingjun Zhao (21763122)

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Effects of busulfan treatment on CX43 and N-Cadherin. حسب Lingjun Zhao (21763122)

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Effects of busulfan treatment on the ultrastructure of the blood-testis barrier (BTB). حسب Lingjun Zhao (21763122)

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Effect of busulfan treatment on the tight junction protein, occludin. حسب Lingjun Zhao (21763122)

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Three-dimensional topography of concrete joints. حسب Zhezhe Zhang (19704587)

الموضوعات:

The relationship between residual shear strength and <i>JRC</i>, normal stress. حسب Zhezhe Zhang (19704587)

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