Data Sheet 3_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf by Tianmin Huang (20561477)

“…</p>Results<p>Two randomized controlled trials (RCTs) and 25 single-armed observational studies with typically 1,748 individuals were involved in our analysis. All 27 clinical trials were reported with fair quality. HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”

Image 1_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf by Youyi Wu (20786402)

“…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …”

Data Sheet 2_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf by Tianmin Huang (20561477)

“…</p>Results<p>Two randomized controlled trials (RCTs) and 25 single-armed observational studies with typically 1,748 individuals were involved in our analysis. All 27 clinical trials were reported with fair quality. HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”

Image 3_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf by Youyi Wu (20786402)

“…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …”

Table 1_Amiodarone treatment in cats: evaluation of indications, adverse effects, and survival outcomes.docx by Graham C. Rossi (20573861)

“…Transient gastrointestinal signs were reported in approximately one-third of the cats studied, but no clinically significant laboratory abnormalities were found in cats receiving amiodarone.…”

Image 4_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf by Youyi Wu (20786402)

“…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …”

Supplementary information files for "Incorporating fluid-structure interactions for modelling of pyramidal hollow microneedles for transdermal drug delivery" by Rahul Nadda (19435999)

“…<p dir="ltr">Supplementary files for article "Incorporating fluid-structure interactions for modelling of pyramidal hollow microneedles for transdermal drug delivery"<br><br>ollow microneedles (HMNs) have gained significant attention as a potential alternative to traditional hypo?…”

Image 5_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf by Youyi Wu (20786402)

“…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …”

Table 1_Assessment of brain atrophy as a promising marker of radiological activity in patients with relapsing–remitting multiple sclerosis.docx by Aleksandra Pogoda-Wesołowska (14589242)

“…In the year-to-year analysis (n_CLAD = 59, n_ALEM = 36) within the CLAD group, new T2 lesions were significantly associated with a decrease in thalamic (p = 0.02), cerebellum (p = 0.05) and deep grey matter (p = 0.05) volume. …”

Image 1_The impact of Internet-based healthcare derived from the COVID-19 pandemic on outpatients in a cardiology department.tif by Jie Liu (15128)

“…</p>Results<p>Compared to the period before online services (T1), the second stage (T2) saw a significant decrease in total offline and general clinic visits. …”

Table 1_Sex-specific association between body mass index and cerebral microbleed progression in adults aged 50–85 years.docx by Cindy W. Yoon (10146428)

“…In women, each 1 kg/m² increase in BMI was significantly associated with a decrease in the 2-year change in the number of total CMBs after adjustment for age and baseline CMB count [β = −0.120, 95% confidence interval (CI): −0.202 to −0.037, p = 0.005]. …”

Data Sheet 1_Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-anal... by Yong Tian (1461202)

“…There was no statistically significant decrease in CD8⁺ cells. For inflammation, lower-dose Tα1 could significantly reduce C-reactive protein (CRP) levels (mg/L) (MD=-30.12, 95%CI [-35.75, -24.49], P<0.00001), while higher-dose Tα1 showed no statistically significant difference (MD=-3.83, 95%CI [-12.14, 4.49], P=0.37). …”

DataSheet1_Targeting AXL cellular networks in kidney fibrosis.docx by Sturla M. Grøndal (20102511)

“…</p>Results<p>Preventive treatment with bemcentinib significantly attenuated fibrosis in the UUO model. The anti-fibrotic effect correlated with a decrease in mesangial cells and inhibition of innate immune cell infiltration, while the proportion of epithelial cells increased. …”

Table 1_Promising benefits of six-month Phaeodactylum tricornutum microalgae supplementation on cognitive function and inflammation in healthy older adults with age-associated memo... by Emily Goodbody (21216737)

“…Similar findings were reported for participants’ perceived stress (p = -0.04; Cohen’s d = 0.4). There was a significant decrease in blood hs-CRP from 3.9mg/L to 2.1mg/L following 24-weeks of Pt extract supplementation as compared to placebo (p = 0.002; Cohen’s d = 0.8), while there was no adverse impact on safety clinical blood tests or reported side effects, with the product deemed safe and tolerable.…”

Data Sheet 1_Psychosocial and physiological health outcomes of outdoor green exercise versus indoor exercise in knee osteoarthritis patients coexisting with type 2 diabetes mellitu... by Yilin Jin (8070026)

“…Participants in OGC group achieved significant decrease of HbA1c than participants in ISC group.…”

Table 1_Affective bias predicts changes in depression during deep brain stimulation therapy.docx by Brian Cui (20932658)

“…Additionally, greater time elapsed since DBS implantation was associated with a decrease in HDRS-17 scores, indicating clinical improvement over time.…”

Table2_Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation.docx by Yangbai- Lu (19955883)

“…This study aimed to explore the clinical significance of novel ClncRNAs in the prognostic assessment of PCa.…”

Table 3_Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis.docx by Tainã Luís de Souza (21574790)

“…This study aims to analyze functional markers of M1 and M2 responses, as well as PD-L1+ macrophages in the spleens of naturally infected dogs with Leishmania infantum, and to correlate these findings with splenic white pulp disorganization, parasitic load, and clinical severity.</p>Methods<p>Thirty-four VL-infected dogs were enrolled, each undergoing clinical evaluation to determine a clinical severity score. …”

Table 1_Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis.docx by Tainã Luís de Souza (21574790)

“…This study aims to analyze functional markers of M1 and M2 responses, as well as PD-L1+ macrophages in the spleens of naturally infected dogs with Leishmania infantum, and to correlate these findings with splenic white pulp disorganization, parasitic load, and clinical severity.</p>Methods<p>Thirty-four VL-infected dogs were enrolled, each undergoing clinical evaluation to determine a clinical severity score. …”

Table1_Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation.docx by Yangbai- Lu (19955883)

“…This study aimed to explore the clinical significance of novel ClncRNAs in the prognostic assessment of PCa.…”