Supplementary Material for: Efficacy and safety of transdermal medical cannabis (THC:CBD: CBN formula) to treat painful diabetic peripheral neuropathy of the lower extremities by Seevathee K. (20196534)

“…The study protocol received approval from the Institutional Review Board of Khon Kaen University and the Kalasin Provincial Public Health Office Ethics Committee, with trial registration in the Thai Clinical Trials Registry. Results: The intervention group demonstrated statistically significant reductions in NPSI-T scores across all measured dimensions (p<0.001). …”

Table 2_L-shaped association between triglyceride-glucose body mass index and short-term mortality in ICU patients with sepsis-associated acute kidney injury.docx by Heping Xu (95297)

“…The Boruta analysis identified the TyG-BMI as an important clinical feature. Higher TyG-BMI values were significantly associated with reduced short-term mortality rates (28, 90, and 180 days) in patients with SA-AKI; for each standard deviation increase in TyG-BMI, the risk of all-cause death decreased by 0.2% (p < 0.0001). …”

Table 1_L-shaped association between triglyceride-glucose body mass index and short-term mortality in ICU patients with sepsis-associated acute kidney injury.docx by Heping Xu (95297)

“…The Boruta analysis identified the TyG-BMI as an important clinical feature. Higher TyG-BMI values were significantly associated with reduced short-term mortality rates (28, 90, and 180 days) in patients with SA-AKI; for each standard deviation increase in TyG-BMI, the risk of all-cause death decreased by 0.2% (p < 0.0001). …”

Table 1_Evaluation of IVIM and FACT imaging for early detection of rotator cuff muscle degeneration and physiotherapy exercise effects.docx by Ling Teng (317759)

“…After the physiotherapy exercise, all of the clinical scores showed significant improvements compared to the baseline (all p < 0.05). …”

Data Sheet 5_Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing.xls by Filippos S. Kardaras (18330696)

“…Microbiome profiling was performed using 16S rRNA gene-targeted metagenomic sequencing, followed by comprehensive bioinformatics and statistical analyses.</p>Results<p>Significant differences were observed in both alpha and beta diversity measures, with alpha diversity decreasing as the severity of COVID-19 increased. …”

Data Sheet 2_Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing.xls by Filippos S. Kardaras (18330696)

“…Microbiome profiling was performed using 16S rRNA gene-targeted metagenomic sequencing, followed by comprehensive bioinformatics and statistical analyses.</p>Results<p>Significant differences were observed in both alpha and beta diversity measures, with alpha diversity decreasing as the severity of COVID-19 increased. …”

Supplementary file 1_Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing.docx by Filippos S. Kardaras (18330696)

“…Microbiome profiling was performed using 16S rRNA gene-targeted metagenomic sequencing, followed by comprehensive bioinformatics and statistical analyses.</p>Results<p>Significant differences were observed in both alpha and beta diversity measures, with alpha diversity decreasing as the severity of COVID-19 increased. …”

Data Sheet 4_Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing.xls by Filippos S. Kardaras (18330696)

“…Microbiome profiling was performed using 16S rRNA gene-targeted metagenomic sequencing, followed by comprehensive bioinformatics and statistical analyses.</p>Results<p>Significant differences were observed in both alpha and beta diversity measures, with alpha diversity decreasing as the severity of COVID-19 increased. …”

Data Sheet 1_Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing.xls by Filippos S. Kardaras (18330696)

“…Microbiome profiling was performed using 16S rRNA gene-targeted metagenomic sequencing, followed by comprehensive bioinformatics and statistical analyses.</p>Results<p>Significant differences were observed in both alpha and beta diversity measures, with alpha diversity decreasing as the severity of COVID-19 increased. …”

Data Sheet 3_Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing.xls by Filippos S. Kardaras (18330696)

“…Microbiome profiling was performed using 16S rRNA gene-targeted metagenomic sequencing, followed by comprehensive bioinformatics and statistical analyses.</p>Results<p>Significant differences were observed in both alpha and beta diversity measures, with alpha diversity decreasing as the severity of COVID-19 increased. …”

Table 1_Telestroke management during the Hajj seasons 2023–2024: insights from SEHA Virtual Hospital in KSA.xlsx by Ghadah Sulaiman Alsaleh (22611695)

“…Male patients rose from 57% in 2023 to 62% in 2024. Diagnoses showed significant variation: ischemic strokes increased from 46% in 2023 to 73% in 2024, while hemorrhagic strokes and other miscellaneous conditions decreased, and TIAs showed a slight increase. …”

Efficacy of Low-Dose Naltrexone in Treating Patients with Fibromyalgia: systematic Review and Meta-Analysis by Abiodun Ologunowa (21343002)

“…This suggests that LDN may not provide significant clinical benefit over placebo in fibromyalgia management, warranting further research.…”

Data Sheet 1_Efficacy and safety of topical minocycline preparations for papulopustular rosacea: a systematic review and meta-analysis.pdf by Awadh Alamri (20970752)

“…Topical minocycline allow the delivery of high concentrations of the medication to the skin while decreasing systemic exposure thereby evading side effects (Jones et al., 2021, Webster et al., 2020). …”

Table 1_A real-world disproportionality analysis of ripretinib data mining of the public version of FDA adverse event reporting system.docx by Yingkai Feng (20893169)

“…These reactions align with the medication instructions and reports from corresponding clinical trials. Notably, the label includes unexpected and significant AEs such as “hepatic neoplasm”, “hair texture abnormal”, “metastases to liver” and “red blood cell count decreased”. …”

Image2_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.tif by Chunjie Liu (3437477)

“…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …”

Raw data for hand and arm dysfunction following hemodialysis access placement by Kyoungrae Kim (10312460)

“…RESULTS: Six weeks post-surgery, patients exhibited significant functional decline in the access limb. Postoperative grip strength declined by approximately 15% (P=0.0015), finger pressure decreased by ~30 mmHg (P<0.0001), and the perceived HAD score increased significantly (P=0.0450) compared to the preoperative values. …”

Table1_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.docx by Chunjie Liu (3437477)

“…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …”

Data Sheet 1_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Supplementary file 1_Multimodal MRI study of gray matter and functional connectivity abnormalities in adolescents with bipolar disorder.docx by Pengyu Zhu (1819939)

“…VBM analysis demonstrated decreased GMV in the left cerebellum. No significant correlations were found between imaging measures and clinical scale ratings.…”

Data Sheet 6_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”