Data Sheet 1_Population pharmacokinetics/pharmacodynamics and safety of YPEG-rhGH in elderly subjects.docx حسب Yajie He (20323682)

"…In the final model, AGE was identified as a significant covariate for K_a, V₁/F, and V_max, while WEIGHT significantly influenced V_max. …"

DataSheet2_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx حسب Marek Sierzega (3846406)

"…Differentially expressed proteins and 5 myokines with increased serum levels generated a significant protein-protein interaction network.</p>Conclusions<p>Our study provides clinical evidence that some myokines are involved in the pathogenesis of cachexia and are well integrated into the regulatory network of circulating blood proteins identified among cachectic patients with gastric cancer.…"

DataSheet4_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Renal function and risk of dementia: a Mendelian randomization study حسب Haowen Huang (1430386)

"…</p> <p>The findings indicate a significant correlation between each unit increase in cystatin C-based estimated glomerular filtration rate (eGFR-cys) levels was significantly associated with a reduction in the incidence of late-onset Alzheimer’s disease (LOAD) (IVW: OR = 0.35, 95% CI: 0.13–0.91, <i>p</i> = 0.031). …"

Data Sheet 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Table 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx حسب Younggwang Kim (21562529)

"…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.…"

Image 1_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.tif حسب Zhengqing Yu (12641890)

"…Background<p>Growing evidence suggests that growth differentiation factor-15 (GDF-15) may contribute to adverse clinical outcomes, such as major cardiovascular events and all-cause mortality. …"

Supplementary Material for: Emergency Renal Replacement Therapy with Manual Dialysis in a Patients with Acute Kidney Injury: First in Human Case Report حسب figshare admin karger (2628495)

"…A total of 600 mL of UF was safely removed (UF rate of 600 mL/h), and the patient demonstrated both clinical and ultrasonographic improvement. Notably, portal vein pulsatility decreased from 38% to 31% following the procedure, indicating a reduction in fluid overload. …"

Image 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif حسب Younggwang Kim (21562529)

"…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.…"

Image 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif حسب Younggwang Kim (21562529)

"…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.…"

DataSheet7_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Table 1_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.docx حسب Yingying Sun (568696)

"…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …"

Image 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.tif حسب Zhengqing Yu (12641890)

"…Background<p>Growing evidence suggests that growth differentiation factor-15 (GDF-15) may contribute to adverse clinical outcomes, such as major cardiovascular events and all-cause mortality. …"

Image 1_Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study.jpeg حسب Renxian Xie (17044863)

"…Notably, HS VMAT plans markedly decreased doses to the ipsilateral hippocampus and the contralateral hippocampus, demonstrating its efficacy in hippocampal dose reduction.…"

Image 3_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif حسب Younggwang Kim (21562529)

"…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.…"

Image 2_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif حسب Younggwang Kim (21562529)

"…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.…"

Table 2_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx حسب Younggwang Kim (21562529)

"…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.…"

DataSheet3_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.xlsx حسب Marek Sierzega (3846406)

"…Differentially expressed proteins and 5 myokines with increased serum levels generated a significant protein-protein interaction network.</p>Conclusions<p>Our study provides clinical evidence that some myokines are involved in the pathogenesis of cachexia and are well integrated into the regulatory network of circulating blood proteins identified among cachectic patients with gastric cancer.…"

Image 1_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif حسب Yingying Sun (568696)

"…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …"

Data Sheet 1_Integrative analysis of DNA methylation, RNA sequencing, and genomic variants in the cancer genome atlas (TCGA) to predict endometrial cancer recurrence.zip حسب Jin Hwa Hong (6523928)

"…Further validation using TCGA clinical data confirmed PARD6G-AS1 hypomethylation and CD44 overexpression as significant indicators of recurrence (p=0.006 and p=0.02, respectively), and both were linked to advanced stage and lymph node metastasis.…"