Supplementary Material for: Impact of Liraglutide 3.0 mg on Metabolic Dysfunction-Associated Steatotic Liver Disease in Individuals with Obesity: A Real-World Study by figshare admin karger (2628495)

“…Hepatic steatosis index (HSI) and non-alcoholic fatty liver disease (NAFLD) liver fat score also decreased significantly (HSI: 44.7 ± 6.2 to 42.2 ± 5.8 p<0.001; NAFLD liver fat score: 2.12 ± 2.90 to 0.43 ± 1.91, p<0.001). …”

Table 2_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Data Sheet 2_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.docx by Quan Lin (5958)

“…SQOR knockdown resulted in decreased cell viability, decreased migration ability and increased MDA level under hypoxic Ersatin induced conditions. …”

Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Mitigation of Senescence Burden in Doxorubicin-Induced Senescent Endothelial Cells by MitoQ Treatment Through Diminishing Mitochondrial ROS and DNA Damage. by Hossein Abdeahad (22177792)

“…DOXO increased mtROS, decreased mitochondrial mass, and induced senescence. …”

Table 1_Complex evaluation of coagulation, fibrinolysis, and inflammatory cytokines in SARS-CoV-2 infected pregnant women: a prospective, case-control study.docx by Zsuzsa Bagoly (429210)

“…Admission IL-1β, and IL-33 were significantly lower, while IL-18 was significantly higher in cases when COVID-19 became more severe, along with significantly decreased FVIII, FXIII and plasminogen. …”

Identification of Alzheimer’s disease susceptibility genes by the integration of genomics and transcriptomics by Chenghong OuYang (13521682)

“…Through Mendelian randomization (MR) analysis, it was found that the risk of AD was significantly increased when VASP expression increased (OR = 0.1.046), while the risk of AD was significantly decreased when SURF2 (OR = 0.897) and TARBP1(OR = 0.920) expression increased. …”

Data Sheet 1_Evaluating the prognostic relevance of neutrophil-to-lymphocyte ratio in cervical cancer: a systematic review and meta-analysis.docx by Xieyan Zhuang (20467625)

“…</p>Conclusion<p>An elevated NLR prior to treatment demonstrates a strong association with decreased OS and PFS among patients with cervical cancer, underscoring the significance of NLR as a prognostic marker within this population.…”

Table 1_Evaluating the prognostic relevance of neutrophil-to-lymphocyte ratio in cervical cancer: a systematic review and meta-analysis.docx by Xieyan Zhuang (20467625)

“…</p>Conclusion<p>An elevated NLR prior to treatment demonstrates a strong association with decreased OS and PFS among patients with cervical cancer, underscoring the significance of NLR as a prognostic marker within this population.…”

Table 1_MicroRNA-31 mediated inhibition of keratin 6 by PSORI-CM01: a novel approach to psoriasis amelioration.pdf by Shilei Wang (3279066)

“…</p>Results<p>In vivo, PSORI-CM01 significantly alleviated the clinical-like manifestations of erythema, scales, and thickening in psoriasis-like mice, and it also reduced the PASI scores; Different concentrations of PSORI-CM01 significantly decreased epidermal thickness and the expression of miR-31 and Krt6 in psoriasis-like mice in a dose-dependent manner. …”

Data Sheet 1_MicroRNA-31 mediated inhibition of keratin 6 by PSORI-CM01: a novel approach to psoriasis amelioration.pdf by Shilei Wang (3279066)

“…</p>Results<p>In vivo, PSORI-CM01 significantly alleviated the clinical-like manifestations of erythema, scales, and thickening in psoriasis-like mice, and it also reduced the PASI scores; Different concentrations of PSORI-CM01 significantly decreased epidermal thickness and the expression of miR-31 and Krt6 in psoriasis-like mice in a dose-dependent manner. …”

Image 6_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…Introduction<p>Pediatric pulmonary arterial hypertension (PAH) is a rare and severe disorder characterized by obstructive vascular changes that can lead to right heart failure. The clinical presentation and underlying causes of pediatric PAH differ significantly from those in adults, often involving congenital heart disease and developmental lung disorders, such as bronchopulmonary dysplasia (BPD). …”

Image 3_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…Introduction<p>Pediatric pulmonary arterial hypertension (PAH) is a rare and severe disorder characterized by obstructive vascular changes that can lead to right heart failure. The clinical presentation and underlying causes of pediatric PAH differ significantly from those in adults, often involving congenital heart disease and developmental lung disorders, such as bronchopulmonary dysplasia (BPD). …”

Image 1_Lipid biomarkers of GVHD in allogeneic stem hematopoietic cell transplantation patients.png by Zhi Lin (281756)

“…</p>Results<p>Profound dyslipidemia was observed post-transplantation, with over 60% of patients developing significantly decreased high-density lipoprotein cholesterol (HDL-C) and elevated triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) compared to baseline. …”

Table 1_Mechanism of action of decitabine in treating acute lymphoblastic leukemia.docx by Xiaohui Gao (308514)

“…Animal experimental results indicated that both DAC and doxorubicin substantially decreased tumor length, width, volume, and mass; however, DAC demonstrated significantly superior efficacy in inhibiting tumor growth compared to doxorubicin.…”

Image 1_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…Introduction<p>Pediatric pulmonary arterial hypertension (PAH) is a rare and severe disorder characterized by obstructive vascular changes that can lead to right heart failure. The clinical presentation and underlying causes of pediatric PAH differ significantly from those in adults, often involving congenital heart disease and developmental lung disorders, such as bronchopulmonary dysplasia (BPD). …”

Image 1_Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation.png by Xing Han (802860)

“…The diameter and number of cancerous foci were significantly decreased in CRC mice treated with FMT, along with the restoration of the intestinal mucosal structure and the lessening of the gland arrangement disorder. …”

Table 2_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx by Lili Deng (152262)

“…Introduction<p>Pediatric pulmonary arterial hypertension (PAH) is a rare and severe disorder characterized by obstructive vascular changes that can lead to right heart failure. The clinical presentation and underlying causes of pediatric PAH differ significantly from those in adults, often involving congenital heart disease and developmental lung disorders, such as bronchopulmonary dysplasia (BPD). …”

Table 1_Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation.docx by Xing Han (802860)

“…The diameter and number of cancerous foci were significantly decreased in CRC mice treated with FMT, along with the restoration of the intestinal mucosal structure and the lessening of the gland arrangement disorder. …”

Data Sheet 1_BRMS1L promotes chemotherapy sensitivity by inhibiting autophagy in breast cancer.docx by Yuan Li (67017)

“…In vitro experiments confirmed that chemoresistant breast cancer cells exhibited decreased BRMS1L expression compared to chemosensitive cells. …”