DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Model inputs. by Natalia Serpetti (5260715)

“…The spatial/temporal model successfully simulated the overall ongoing declining dynamics of the Black Sea ecosystem as the biomasses of the majority of the functional groups had significant observed decreasing trends during the simulation period. …”

Table 1_Trends in the burden of chronic diseases attributable to diet-related risk factors from 1990 to 2021 and the global projections through 2030: a population-based study.docx by Huan Ma (713125)

“…In low-SDI regions, diets low in vegetables showed the strongest association with neoplasm-related mortality, while diets low in fruits were significantly linked to CVD and diabetes burden. High-sodium diet was a significant risk factor for CVD in the middle-SDI regions. …”

Supplementary file 1_Spatiotemporal monitoring in beidagang wetland using Landsat time-series images and Google Earth Engine during 2000–2022.docx by Xinyue Zhang (271120)

“…Frequent type conversions occurred between adjacent classes, with the most significant changes in Guanqi Lake. Despite declining wetland water volumes due to rising temperatures and reduced precipitation, ecological compensation measures, including functional zoning, water replenishment, and phragmites restoration, have continuously improved the wetland environment. …”

Table 1_Serum neurotransmitter analysis of motor and non-motor symptoms in Parkinson’s patients.docx by Yichun Fan (14295492)

“…Specifically, levels of Trp, kynurenine (KYN), kynurenic acid (KA), nicotinamide (NAM), and 5-methoxyltryptamine (MeOTA) were substantially decreased. Additionally, three other excitation/inhibiting amino acids—glutamic acid (Glu), 4-aminobutyric acid (GABA), and aspartic acid (Asp)—also declined. …”

Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus by Jian Sun (27858)

“…</p> <p>Compared to the HC group, SLE patients exhibited a decline in both Lyn mRNA and protein expression in PBMCs, with significant downregulation in the high SLEDAI group versus the low SLEDAI group and a notable reduction in the LN group relative to the non-LN group. …”

DataSheet1_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.pdf by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Data and code from: Limited responses of lizard assemblages to experimental fire regimes in an Australian tropical savanna by angga rachmansah (22007819)

“…The abundance of only one of the five most common species was significantly related to fire frequency. Species richness decreased with increased fire frequency and showed a humped relationship with woody cover. …”

Table 2_Does COVID-19 vaccination affect risk perception and adherence to preventive behaviors? A systematic review and meta-analysis.docx by Michele Sorrentino (16538214)

“…Most vaccinated individuals maintained preventive behaviors despite stable or declining risk perception, though social distancing and hand hygiene adherence decreased over time. …”

DataSheet1_Apoptotic and proliferative processes in the small intestine of rats with type 2 diabetes mellitus after metformin and propionic acid treatment.PDF by Larysa Natrus (9397898)

“…While metformin inhibited apoptosis via Bax declining, PA mainly acted via caspase-3-dependent mechanism elevating its active p17 subunit.…”

Supplementary file 1_Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area.doc by Jianhua Li (36075)

“…Results showed that (1) Compared to R0, the R10 treatment resulted in significant increases in soil organic matter (SOM), total nitrogen (TN), available phosphorus (AP), and available potassium (AK) by 2.1-fold, 1.3-fold, 1.5-fold, and 0.4-fold, and also in activities of β-glucosidase (BG), N-acetyl-β-glucosaminidase (NAG), and leucine aminopeptidase (LAP), by 17-fold, 8.7-fold, and 1.8-fold, respectively (p < 0.05). (2) Rising bacterial diversity (Shannon, Chao1) over time, contrasting with fungal diversity that declined initially before recovering. (3) As the reclamation progressed, the network complexity was increased for both bacteria and fungi, improving stability. …”

Table 4_Does COVID-19 vaccination affect risk perception and adherence to preventive behaviors? A systematic review and meta-analysis.docx by Michele Sorrentino (16538214)

“…Most vaccinated individuals maintained preventive behaviors despite stable or declining risk perception, though social distancing and hand hygiene adherence decreased over time. …”

Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”

<b>Species richness, composition and dominance of core and climate relicts of African Miombo woodlands</b> by Justice Muvengwi (22631075)

“…Our results revealed a pattern where species richness, the Shannon Wiener index, and evenness increased with decreasing relict size. Interestingly, evenness declined from juvenile to adult stages within sites, suggesting changes in species composition over time. …”

Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX by Shaoqun Huang (19810725)

“…The fully adjusted models showed decreased 0.20 years in phenotypic age [−0.20 (−0.31, −0.10)] and declined 0.54 years in biological age [−0.54 (−0.69, −0.38)] correlated with PHDI per 10 scores increment. …”

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx by Chunmei Wu (3202050)

“…B cell counts declined rapidly and began to repopulate from week 36. …”

Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”

Table 4_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx by Wang Yu (8537490)

“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”

Table1_Age and gender influence on clinical manifestations of thyroid-associated ophthalmopathy: a case series of 2479 Chinese patients.xlsx by Mei Yang (51996)

“…Background<p>Significant individual differences exist in the clinical manifestations of thyroid-associated ophthalmopathy (TAO). …”

Table 1_Forest bathing enhances sleep, mood, and immunity: insights from low-latitude evergreen broad-leaved forests.xlsx by Xiangheng Dai (21684431)

“…POMS and PSS scores declined, indicating mood and stress improvements. …”