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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant declines » significant decline (Expand Search), significantly declined (Expand Search), significant genes (Expand Search)
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1801
Data Sheet 1_Particulate matter pollution and older adult health: global trends and disparities, 1991–2021.docx
Published 2024“…However, age-standardized mortality rate decreased from 384 to 337 per 100,000. HAP-SF-related deaths decreased from 2,700,000 to 2,100,000, and DALYs from 54,000,000 to 42,000,000. …”
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1802
Table 2_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.docx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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1803
Table 1_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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1804
Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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1805
Table 1_Socio-hydrology and sustainable tank management: empirical case from a Mailam tank cascade, Tamil Nadu, India.xlsx
Published 2025“…The dependence on tanks for irrigation by farmers in the study area has decreased, ranging from 9 to 54%. There has been a significant change in land use; a 44% reduction in the area under cropping (1,707 ha to 954 ha), with a 13% increase in fallow land (1,607 ha to 1,822 ha) and a 43% increase in other vegetation and built-up area from 5 ha to 60 ha. …”
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1806
Data Sheet 2_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip
Published 2025“…Results indicate a substantial decline in PM<sub>2.5</sub>-attributable mortality over the study period. …”
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1807
Data Sheet 1_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip
Published 2025“…Results indicate a substantial decline in PM<sub>2.5</sub>-attributable mortality over the study period. …”
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1808
Supplementary file 1_Global burden of HIV, syphilis, and HBV infection among women of childbearing age and children under five: based on the Global Burden of Diseases Study 2021.do...
Published 2025“…Both the ASPR of HBV infection among WCBA and the ASIR among children under five declined significantly from 1990 to 2021, with average annual percentage changes of −1.25% and −4.14%, respectively. …”
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1809
Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx
Published 2025“…Background<p>Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. …”
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1810
Data Sheet 3_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip
Published 2025“…Results indicate a substantial decline in PM<sub>2.5</sub>-attributable mortality over the study period. …”
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1811
Ambient Air Pollutant Dynamics (2010–2025) and the Exceptional Winter 2016–17 Pollution Episode: Implications for a Uranium/Arsenic Exposure Event
Published 2025“…</li><li><b>Long-Term Trends:</b> The complete time series reveals significant downward trends in NO₂, EC, and SO₂ over the ~15-year period. …”
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1812
Data Sheet 1_Temperature extremes across elevation gradients: evidence from two German mountain observatories.pdf
Published 2025“…Temperature extremes have also changed markedly: cold extremes have declined significantly at both locations (e.g., the duration of cold spells has decreased by 16 days at Hohenpeißenberg and by 10 days at Zugspitze, over the period 1981–2024), while warm extremes exhibit a pronounced rise, especially in the Warm Spell Duration Index (WSDI), which has nearly doubled since the 1980s. …”
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1813
Table 1_Long-term oyster shell powder applications increase crop yields and control soil acidity and cadmium in red soil drylands.docx
Published 2025“…While all treatments showed an annual decline in peanut yield from 2013 to 2018, but oyster shell applications significantly reduced the rate of crop yield decline. …”
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1814
Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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1815
Image 4_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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1816
Data Sheet 1_Dynamic stability of gut microbiota in elite volleyball athletes: microbial adaptations during training, competition and recovery.pdf
Published 2025“…Mediterranean diet adherence declined during Regular Season Periods (T0: 6.3 ± 1.5, T1: 5.5 ± 0.8), while stool consistency gradually improved.…”
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1817
Image 2_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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1818
Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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1819
Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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1820
Supplementary file 1_Effects of different urban vegetation cover and green space types on soil greenhouse gas emissions and carbon sequestration.docx
Published 2025“…In comparison to park green spaces, the CO<sub>2</sub> flux of residential and street soils decreased by 2.11% and 3.25%, respectively, while the N<sub>2</sub>O flux dropped by 16.61% and 22.41%, respectively. …”