يعرض 20,661 - 20,680 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant effect decrease ))*', وقت الاستعلام: 0.53s تنقيح النتائج
  1. 20661

    Image 12_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg حسب Chen Wang (88408)

    منشور في 2025
    "…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…"
  2. 20662

    Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx حسب Wenqiao Jia (12356306)

    منشور في 2025
    "…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca<sup>2+</sup>/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…"
  3. 20663

    Image 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... حسب Ting Yang (189879)

    منشور في 2025
    "…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …"
  4. 20664

    Supplementary file 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.docx حسب You Yu (2102071)

    منشور في 2025
    "…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …"
  5. 20665

    Table 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx حسب M. Elakkya (21760439)

    منشور في 2025
    "…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …"
  6. 20666

    Image 4_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... حسب Ting Yang (189879)

    منشور في 2025
    "…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …"
  7. 20667

    DataSheet_1_RETRACTED: Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia.docx حسب Youfeng Zhu (2460811)

    منشور في 2024
    "…Depletion of macrophages protected against lung epithelial cells and significantly decreased MMP9, MMP19, FTH, and FTL expression levels and increased GPX4 expression levels, while partially reversing the changes in macrophage. …"
  8. 20668

    Image 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... حسب Yun Zhao (48978)

    منشور في 2025
    "…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…"
  9. 20669

    Table 1_Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.docx حسب Hua-Liang Li (20812799)

    منشور في 2025
    "…</p>Results<p>Compared to healthy controls, medication-naïve patients with BSP exhibited significantly increased ALFF in the bilateral putamen and left premotor cortex and decreased ALFF in the bilateral thalamus (p < 0.05, threshold-free cluster enhancement with family-wise error correction for multiple comparisons). …"
  10. 20670

    Table 1_Socioeconomic status and motor coordination function among children with autism.docx حسب Muqing Cao (8308815)

    منشور في 2025
    "…Mothers without a college degree showed a decreased likelihood of probable DCD (OR: 0.33, 95%CI: 0.15-0.71).…"
  11. 20671

    Table 7_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx حسب M. Elakkya (21760439)

    منشور في 2025
    "…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …"
  12. 20672

    Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf حسب Miles Anderson-Watters (20626604)

    منشور في 2025
    "…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …"
  13. 20673

    MCT4/CD147 transporter complex-associated cell proliferation, migration and invasion in U87 and U251 cell lines. حسب Chen Gao (159491)

    منشور في 2024
    "…The curves constructed from independent experiments revealed decreased cell proliferation in MCT4 and CD147 siRNA interference cells, but increased cell proliferation in lentivirus-transduced cells. …"
  14. 20674

    Data_Sheet_4_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF حسب Joseph H. Skarlupka (5830637)

    منشور في 2024
    "…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …"
  15. 20675

    Supplementary Material for: Retrospective Analysis of Allergen Characteristics in Patients with Allergic Diseases in Sanmen, Zhejiang Province حسب figshare admin karger (2628495)

    منشور في 2025
    "…The positivity rate for serum total IgE was 25.67%, significantly higher than the IgE prevalence of inhalant allergens (24.84%) and food allergens (12.48%), significantly higher than the positivity rate for food allergen sIgE at 12.48% (P<0.001). …"
  16. 20676

    Image 1_Double-lumen tubes verus single-lumen tube in patients undergoing minimally invasive cardiac surgery: a randomised, controlled clinical trial.pdf حسب Zhenzhong Wang (407028)

    منشور في 2025
    "…</p>Conclusions<p>Two-lung ventilation with single-lumen tube is easy to perform, significantly increases oxygenation, and decreases the incidence of postoperative complications and airway injuries. …"
  17. 20677

    Table 1_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx حسب Nianfeng Tang (21536069)

    منشور في 2025
    "…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…"
  18. 20678

    Data Sheet 1_N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder.pdf حسب Etna J. E. Engeli (20793524)

    منشور في 2025
    "…While N-acetylcysteine showed no impact on subjectively rated cocaine craving, neural cue reactivity in the superior frontal gyrus was significantly decreased under N-acetylcysteine compared to placebo.…"
  19. 20679

    Table 3_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx حسب Nianfeng Tang (21536069)

    منشور في 2025
    "…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…"
  20. 20680

    Data_Sheet_7_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF حسب Joseph H. Skarlupka (5830637)

    منشور في 2024
    "…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …"