يعرض 20,741 - 20,760 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant effect decrease ))', وقت الاستعلام: 0.37s تنقيح النتائج
  1. 20741

    Image 5_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif حسب Si-Ting Huang (5591432)

    منشور في 2025
    "…Inhibition of TRPA1 or administration of recombinant IL-18 significantly reduced DNFB-induced itch behavior in Nlrp3-/- mice. …"
  2. 20742

    The recruitment of Paf1C to the <i>frq</i> ORF is regulated by the WCC activity. حسب Mengmeng Zhou (9197699)

    منشور في 2025
    "…<p>(A) The enrichment of PAF-1 (Left) or RTF-1 (Right) at the <i>frq</i> ORF middle region significantly decreased in <i>wc-2</i><sup><i>KO</i></sup> strain at DD14. …"
  3. 20743

    Data Sheet 1_Transcriptomic analysis of ROS1+ non-small cell lung cancer reveals an upregulation of nucleotide synthesis and cell adhesion pathways.pdf حسب Marc Terrones (18094462)

    منشور في 2024
    "…When comparing ROS1+ tumor versus cell line transcriptomes, an upregulation of MYC and MET was found in cell lines together with a significantly decreased expression of HER3, HER4 and BRAF. …"
  4. 20744

    Data Sheet 1_Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on... حسب Rui Yang (293531)

    منشور في 2025
    "…During dynamic activities, muscle fatigue was exacerbated in the abnormal curvature group: during extension, the left UT showed significantly decreased MPF (p < 0.01) and MF (p < 0.05); during flexion, the left SCM exhibited significantly increased MPFs (p < 0.05) and MFs (p < 0.01). …"
  5. 20745

    Table 1_Transcriptomic analysis of ROS1+ non-small cell lung cancer reveals an upregulation of nucleotide synthesis and cell adhesion pathways.xlsx حسب Marc Terrones (18094462)

    منشور في 2024
    "…When comparing ROS1+ tumor versus cell line transcriptomes, an upregulation of MYC and MET was found in cell lines together with a significantly decreased expression of HER3, HER4 and BRAF. …"
  6. 20746

    Table 1_Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on surfa... حسب Rui Yang (293531)

    منشور في 2025
    "…During dynamic activities, muscle fatigue was exacerbated in the abnormal curvature group: during extension, the left UT showed significantly decreased MPF (p < 0.01) and MF (p < 0.05); during flexion, the left SCM exhibited significantly increased MPFs (p < 0.05) and MFs (p < 0.01). …"
  7. 20747

    Data_Sheet_1_Analysis of the global burden of cardiovascular diseases linked to exposure to ambient particulate matter pollution from 1990 to 2019.docx حسب Binbin Zou (11358315)

    منشور في 2024
    "…</p>Conclusion<p>The burden of CVDs linked to PM pollution has grown significantly from 1990 to 2019, with variations across regions and countries, highlighting the need for targeted prevention and pollution management strategies.…"
  8. 20748

    Therapeutic efficacy of Clrn1 re-expression in Müller glia depends on expression level. حسب Hannah J. T. Nonarath (20861735)

    منشور في 2025
    "…(*p<0.05, **p<0.01, ***p<0.005, ****p<0.001; Two-way ANOVA; Significance shown compared to wild-type <i>gfap</i>:GFP without light stress). …"
  9. 20749

    The T-type voltage-gated Ca<sup>2+</sup> channel Ca<sub>V</sub>3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin حسب Haixin Bi (6867632)

    منشور في 2025
    "…This was evidenced by a decreased expression of tight junctions (ZO-1, occludin) and adherens junctions (β-catenin, E-cadherin), as well as enhanced cytoskeletal rearrangement. …"
  10. 20750

    Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg حسب Zexin Zhang (7507979)

    منشور في 2024
    "…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…"
  11. 20751

    The quality metrics of 4C-seq data. حسب Tingting Jiang (169999)

    منشور في 2025
    "…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"
  12. 20752

    <i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor حسب Mo-Fei Li (21624535)

    منشور في 2025
    "…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …"
  13. 20753

    Generated spline library. حسب Zhe Hu (787283)

    منشور في 2025
    "…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…"
  14. 20754

    Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf حسب Qi Dong (119569)

    منشور في 2025
    "…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"
  15. 20755

    Data Sheet 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx حسب Peijin Li (220400)

    منشور في 2025
    "…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …"
  16. 20756

    Supplementary file 2_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

    منشور في 2025
    "…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"
  17. 20757

    Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

    منشور في 2025
    "…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"
  18. 20758

    Image 6_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg حسب Ming Lei (161082)

    منشور في 2024
    "…The study of the supply of ecosystem services and the demand and consumption of ecosystem services by human society, and the analysis of the supply and demand characteristics and flow relationships of ecosystem service flows are of great significance for the management of regional ecosystems and the development of ecological compensation. …"
  19. 20759

    Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx حسب Mallory A. Perry-Eaddy (20842868)

    منشور في 2025
    "…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …"
  20. 20760

    Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc حسب Mengjie An (9501175)

    منشور في 2025
    "…The results showed that salt stress reduced the contents of K<sup>+</sup> and Ca<sup>2+</sup> and enhanced the content of Na<sup>+</sup> in cotton leaves compared to the control, which inhibited leaf photosynthesis and seedling growth. COS-PA application decreased leaf Na<sup>+</sup> content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca<sup>2+</sup> content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …"