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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant effect » significant impact (Expand Search)
effect decrease » effects decreased (Expand Search)
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21221
Decision curves.
Published 2025“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”
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21222
The Type I JAKinib, ruxolitinib, promotes pJAK1 and pJAK2 phosphorylation in MSCs from salivary glands.
Published 2025“…Error bars represent standard deviation; *p = 0.05; p = **** < 0.0001 represent the ANOVA-derived significance for the difference between all values. I = IFN.…”
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21223
Table3_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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21224
Supplementary file 1_Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language...
Published 2025“…In English reports, it matched mainstream AI in lesion analysis (p > 0.05) but excelled in lymph node/pathology metrics (p < 0.05). Task load scores decreased by 38.3% post-implementation (413.90 ± 78.09 vs. 255.30 ± 65.50, t = 26.481, p < 0.001).…”
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21225
Data Sheet 1_Influence of age-adjusted shock index trajectories on 30-day mortality for critical patients with septic shock.zip
Published 2025“…KM curve revealed significantly higher 30-day mortality in Class 2 (32.1%) and Class 3 (38.7%) than Class 1 (12.3%) (P < 0.001). …”
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21226
Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx
Published 2025“…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …”
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21227
The result of the Negative Binomial Regression.
Published 2025“…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…”
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21228
Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg
Published 2024“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”
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21229
Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip
Published 2025“…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …”
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21230
Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx
Published 2025“…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …”
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21231
<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation
Published 2025“…Invasive strains exhibited significantly enhanced serum resistance (>17-fold survival in 75% isolates) and HeLa cell invasive ability (minimum bacterial loads 3.93 × 10⁵ CFU/mL) compared to non-invasive strains (< 9.8-fold survival; maximum bacterial loads 1.47 × 10⁵ CFU/mL). …”
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21232
Presentation 1_Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients.pptx
Published 2024“…Concurrently, 14 soluble immune checkpoints were analyzed by Luminex assay. Immunotherapy significantly increased the levels of Ki67<sup>+</sup>(total and CD8<sup>+</sup>) T cells, PMN(Lox1<sup>+</sup>)-MDSCs, non-suppressive Tregs (nsTregs), and soluble PD1 from T0 to T1 in the entire NSCLC population, while decreased active Tregs. …”
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21233
Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
Published 2025“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”
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21234
Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21235
Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21236
Table 5_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21237
Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21238
Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21239
Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21240
H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin.
Published 2025“…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. (G) Heatmaps depicting H3K9ac CUT&RUN data within loci harboring both H2AK119ub and H3K27me3. …”