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significant effect » significant impact (Expand Search)
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18641
Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf
Published 2025“…Mice subjected to middle cerebral artery occlusion (MCAO) exhibited significant reductions in infarct size and brain edema, prolonged post-MCAO survival, and improved behavioral outcomes following aCD19 Ab treatment. …”
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18642
Supplementary file 1_Proof-of-concept of a prior validated LC-MS/MS method for detection of N-lactoyl-phenylalanine in dried blood spots before, during and after a performance diag...
Published 2025“…No statistically significant correlations were identified between lac-phe and lactate, glucose as well as anthropometric and respiratory parameters.…”
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18643
Table 1_Probabilistic human health risk assessment of commercially supplied jar water in Gopalganj municipal area, Bangladesh.docx
Published 2024“…<p>Every day, the amount of quality fresh water decreases notably due to contamination of drinking water. …”
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18644
Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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18645
Image 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”
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18646
Table 7_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx
Published 2025“…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …”
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18647
Impact of COVID-19 on early intervention referrals (Zellner et al., 2025)
Published 2025“…</p><p dir="ltr"><b>Conclusions: </b>The onset of the pandemic was associated with significant disruption to EI service provision, the magnitude of which varied across states. …”
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18648
Figure 3 from Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRP...
Published 2025“…The left shifts of the peaks seen in the sensitive cell lines indicate decreased mitochondrial membrane potential. Carbonyl cyanide-<i>p</i>-trifluoromethoxyphenylhydrazone, an uncoupler of oxidative phosphorylation, was used as the positive control. …”
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18649
Data Sheet 1_EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures.pdf
Published 2025“…The clay mineralogy was significantly preserved. The slight changes observed in the other properties were opposite depending on the heating conditions: in the case of evaporation, the cation exchange capacity, specific surface area, sorption coefficients, and sometimes swelling pressure decreased. …”
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18650
Quantitative results on WEDU dataset.
Published 2024“…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …”
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18651
Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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18652
Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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18653
Image1_Association between vitamin C intake and thyroid function among U.S. adults: a population-based study.tiff
Published 2024“…</p>Results<p>After adjusting for covariates, our research found a significant inverse correlation between vitamin C intake and total thyroxine (TT4) (β= -0.182, P= 0.006). …”
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18654
Data Sheet 1_CARTOON-based educational intervention for children to foster hygiene knowledge and emotional resilience in preschool children: a randomized controlled trial.pdf
Published 2025“…Additionally, anxiety scores significantly decreased in the intervention group post-intervention compared to baseline (2.2 ± 1.7 vs. 5.6 ± 2.5; p = .01). …”
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18655
Table 1_Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study.docx
Published 2025“…Introduction<p>Chronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. …”
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18656
Data Sheet 1_Altered immune cell profiles in blood of mature/peripheral T-cell leukemia/lymphoma patients: an EuroFlow study.docx
Published 2025“…In contrast, SS/MF showed neutrophilia, associated with decreased numbers of dendritic cells and NK-cells, potentially reflecting their increased migration from blood to the skin. …”
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18657
Table 13_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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18658
Table 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”
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18659
Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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18660
Data Sheet 1_Increased epicardial tissue and reduced TAPSE and MAPSE scores in borderline personality disorders. Early indicators for cardiovascular risk?.pdf
Published 2025“…Additionally, significant decreases in right (TAPSE) and left (MAPSE) ventricular function, albeit within the normal range, were measured in BPD patients. …”