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8501
Reliable high-PAP-1-loaded polymeric micelles for cancer therapy: preparation, characterization, and evaluation of anti-tumor efficacy
Published 2025“…These self-assembled micelles exhibited high entrapment efficiency (91.35%) and drug loading level (8.30%). As pH decreased, the micelles exhibited a significant increase in particle size and zeta potential, accompanied by a surge in PAP-1 release. …”
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8502
Table 1_Late-onset first epileptic seizure and cerebral small vessel disease: role of juxtacortical white matter lesions.docx
Published 2025“…With regard to total WML volume, LOFES and TIA patients did not differ significantly. Compared to TIA group, LOFES patients gray matter volume was regionally decreased in the right pre- and postcentral gyrus.…”
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8503
Insight into Greenhouse Gas Emission Characteristics of Light-Duty Vehicles in China Driven by Technological Innovation
Published 2024“…As anticipated, with advancements in emission standards and powertrains, vehicular GHG emissions have significantly decreased. However, our findings also revealed surprising trends. …”
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8504
Table 1_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc
Published 2025“…Pegylated liposomal doxorubicin (PLD) has been developed to enhance the efficacy of DOX and mitigate its cardiotoxic effects. However, PLD is associated with adverse reactions (ADRs) such as hand-foot syndrome (HFS) and oral mucositis (OM), which have garnered significant attention. …”
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8505
Data Sheet 1_Fatty acid metabolism after short-term fasting: POMC response and EPA signal maintain homeostasis in tilapia.zip
Published 2025“…After fasting, the neuropeptide Y signals in the preglomerular nucleus region increased significantly, while the POMC in the lateral tuberal nucleus significantly decreased. …”
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8506
Table 1_Impact of removing laver (Porphyra) farming racks on the distribution, diversity and foraging behavior of waterbirds in coastal wetlands in eastern China.xlsx
Published 2025“…Notably, the numbers of ducks, plovers, and sandpipers increased significantly, while gull numbers decreased significantly, likely due to habitat structure loss. (3) The proportion of foraging behaviors of 4 common waterbird species increased significantly after restoration, while the percentage of resting behavior significantly decreased. (4) No significant differences in macrobenthos species richness, abundance, biomass or α-diversity indices were detected post-restoration, but the macrobenthos in laver racks area (lower tidal zone) were significantly more abundant than those in the non-racks area (middle tidal zone).…”
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8507
Table 3_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc
Published 2025“…Pegylated liposomal doxorubicin (PLD) has been developed to enhance the efficacy of DOX and mitigate its cardiotoxic effects. However, PLD is associated with adverse reactions (ADRs) such as hand-foot syndrome (HFS) and oral mucositis (OM), which have garnered significant attention. …”
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8508
Trends in management of central cord syndrome: Insights from the New York State SPARCS database
Published 2025“…Chi-square, T-test, and multivariable regression were used to compare outcomes, with random intercepts and effects for facilities. P < 0.05 was considered significant.…”
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8509
Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf
Published 2025“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”
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8510
Droperidol is associated with reduced length of stay in the treatment of cannabinoid hyperemesis syndrome
Published 2025“…<p>Droperidol is a butyrophenone-class drug with potent antiemetic properties that may be useful for treating the acute symptoms of cannabinoid hyperemesis syndrome. We evaluated the effectiveness of droperidol in emergency department patients with cannabinoid hyperemesis syndrome.…”
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8511
Table1_Interannual hydrological changes affect plant communities across different elevation zones in plateau lakeshores: insights from Lake Erhai.docx
Published 2024“…The results showed that (1) In drought years, the Shannon-Wiener index of plants significantly decreased across the three elevation ranges, and other plant diversity indices, biomass, and coverage also decreased to varying degrees; (2) except for soil pH, soil water (SW) and nutrient content decreased to varying degrees in the drought year; (3) SW was the primary factor influencing plant biomass, coverage, and diversity in the 1965.0-1965.3m and 1965.3-1965.6m ranges; nitrate nitrogen, C/N ratio, total phosphorus were the primary factors in the 1965.6-1966.4m ranges. …”
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8512
Video 1_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.mp4
Published 2024“…After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”
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8513
Image 1_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.jpeg
Published 2024“…After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”
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8514
Video 2_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.mp4
Published 2024“…After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”
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8515
Table 1_Xinli formula’s efficacy in heart failure: analysis via Guangdong TCM hospital database.docx
Published 2025“…MLHFQ scores decreased from 45 to 30. Inflammatory markers and NT-proBNP levels also improved significantly.…”
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8516
<b>Three-dimensional analysis of the horizontal condylar angle in the temporomandibular joint: morphology and surgical implications</b>
Published 2025“…In the disc repositioning group, HCA decreased significantly after surgery.<b>Conclusions. …”
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8517
Image 1_Comparative urine proteomic study involving papillary thyroid carcinoma and benign thyroid nodules.jpeg
Published 2025“…Compared with benign nodules, papillary carcinomas showed significant increases and decreases in the levels of 169 and 27 proteins, respectively. …”
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8518
Table 2_Comparative urine proteomic study involving papillary thyroid carcinoma and benign thyroid nodules.xlsx
Published 2025“…Compared with benign nodules, papillary carcinomas showed significant increases and decreases in the levels of 169 and 27 proteins, respectively. …”
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8519
Exploring the variations and potential of carbon stock in the tropical dry deciduous forests of West Bengal, India
Published 2025“…<p>Each pool of the forest ecosystem plays a significant role, as they are interconnected and store atmospheric carbon. …”
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8520
Dual action of novel 5-nitroguaiacol-based hydrazones: Targeting aldolase-a and inducing apoptosis in lung cancer
Published 2025“…Their <i>in vitro</i> cytotoxic effects were evaluated against human non-small cell lung cancer (A549) and normal bronchial epithelial cell lines (BEAS-2B) using the MTT assay. …”