Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf by Lucyna Widacha (20981330)

“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”

Table 2_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 4_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 5_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 1_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 3_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…”

Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... by Wenjing He (4278625)

“…</p> <p>This study investigates rhubarb’s therapeutic effects and underlying mechanisms in CKD.</p> <p>High-performance liquid chromatography (HPLC) established a rhubarb fingerprint to ensure quality control. …”

<b>Targeted Metabolomic Profiling Reveals Inflammation – Associated longitudinal</b><b>changes in Plasma Metabolites Following on-pump Coronary Bypass Surgery</b> by Frieder Neu (18393729)

Table 1_Correlation of serum irisin levels with diabetic nephropathy: an exhaustive systematic appraisal and meta-analytical investigation.xls by Yuan Deng (177795)

“…In terms of renal function, patients with eGFR < 60 mL/min/1.73 m² exhibited lower irisin concentrations than those with preserved renal function (MD = 3.43, 95% CI: –2.90 to 9.75, I² = 90%), though this difference was not statistically significant. Given the substantial heterogeneity among the included studies, random-effects models were applied for all analyses. …”

Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif by Bojun Chen (317487)

“…</p>Conclusion<p>This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.…”

Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx by Xiaoting Gu (3368495)

“…Introduction<p>Chemotherapy induced constipation (CIC) is a gastrointestinal side effect that occurs in patients receiving chemotherapy, which can further deteriorate the living quality of cancer patients. …”

Analytic framework. by Muayad Albadrani (7495145)

“…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. Specifically, Households in the highest income quartile showed a 22% reduction progressively in the odds of mortality risk compared to the lowest income quintile. …”

In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma by Joaquín Yanes-Díaz (20539584)

“…First, we evaluated the effect of NP-427 on tumor growth by measuring tumor volume, mouse weight, survival, and the development of tumor ulceration and necrosis. …”

Image 4_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tiff by Asma Bibi (12057986)

“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”