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9461
Table 2_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx
Published 2025“…In ANXA2-silenced cells, it showed no anti-inflammatory effect. Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. …”
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9462
Data Sheet 2_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip
Published 2025“…Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. All were significantly upregulated in ICH tissues and plasma, correlating with immune cell infiltration. …”
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9463
ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
Published 2025“…Importantly, we observe an increase in Abraxane uptake and a synergistic effect when combined with ELOVL6 interference in vitro. …”
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9464
Table 1_Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice.docx
Published 2025“…These mice were fed with a high-fat diet for 9 weeks to induce inflammation. The effects of conditional knockdown of hepatic PCSK9 on inflammation and the underlying mechanisms were investigated by molecular biological techniques. …”
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9465
DataSheet1_Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption.DOC
Published 2024“…</p>Results<p>Gavage of Scu significantly decreased the DAI score, improved colon shortening, ameliorated the pathological score in DSS-treated mice with better efficacy than the positive drug, 5-aminosalicylic acid. …”
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9466
Table_1_Correlation between ratio of fasting blood glucose to high density lipoprotein cholesterol in serum and non-alcoholic fatty liver disease in American adults: a population b...
Published 2025“…Background<p>Based on previous research, elevated fasting blood glucose (FBG) and decreased high-density lipoprotein cholesterol (HDL-C) levels are associated with non-alcoholic fatty liver disease (NAFLD). …”
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9467
Table 1_Working like a mule? The physiological toll of heavy loads on mules.docx
Published 2025“…Linear mixed models were applied to evaluate the effects of load, time, and body size.</p>Results<p>The size of the mule did not have an effect on their physiological response to work. …”
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9468
Table1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.xlsx
Published 2024“…PKM1 inhibited MyHC1 and MyHC2a expression but promoted MyHC2b expression. SDSS also significantly attenuated the effects of PKM1 on muscle fiber-related gene expression in C2C12 cells. …”
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9469
Data Sheet 3_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The molecular docking results suggested that β-sitosterol could bind effectively to six core targets. The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …”
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9470
DataSheet2_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.pdf
Published 2024“…PKM1 inhibited MyHC1 and MyHC2a expression but promoted MyHC2b expression. SDSS also significantly attenuated the effects of PKM1 on muscle fiber-related gene expression in C2C12 cells. …”
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9471
Data Sheet 2_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The molecular docking results suggested that β-sitosterol could bind effectively to six core targets. The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …”
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9472
Conditional Knockout of Serine Racemase in Microglia Alleviates Alzheimer -like Pathology and Behavior by Reducing Neuroinflammation through Enhancing Histone Lactylation
Published 2025“…In the aging brain, SR expression decreases in neurons, while it becomes more abundant in glia cells in AD. …”
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9473
DataSheet1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.docx
Published 2024“…PKM1 inhibited MyHC1 and MyHC2a expression but promoted MyHC2b expression. SDSS also significantly attenuated the effects of PKM1 on muscle fiber-related gene expression in C2C12 cells. …”
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9474
Table 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.docx
Published 2024“…The molecular docking results suggested that β-sitosterol could bind effectively to six core targets. The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …”
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9475
Data Sheet 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The molecular docking results suggested that β-sitosterol could bind effectively to six core targets. The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …”
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9476
Figure 2 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma
Published 2025“…<b>A,</b> In subcutaneous AB12 mouse mesothelioma tumors, TI significantly decreased the median tumor growth time to 400 mm<sup>3</sup> from 7 days compared with 9 days in untreated TC (<i>P</i> = 0.025). …”
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9477
Excel raw data.
Published 2025“…<div><p>Background</p><p>Antimicrobial resistance is a major public health problem worldwide, particularly in developing countries. The effectiveness of currently available antimicrobial is decreasing due to the increasing prevalence of resistant strains among bacterial isolates. …”
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9478
SLMO is required for the proper function of PISD.
Published 2024“…<p>(A) Schematic of the genome-wide RNAi screen for factors that prevent the rescue effects of PISD on the ERG defects of <i>pect</i><sup><i>RNAi</i></sup>. …”
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9479
Raw data for figures and tables in the paper.
Published 2024“…We employed broth culture and pot experiments to investigate the effect of the inoculation of <i>P</i>. <i>rwandensis</i> on Pb immobilization in the soil, the soil nutrients, the microbial community, and Pb accumulation in the biomass of maize (<i>Zea mays</i> L.). …”
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9480
GnRH antagonist impairs the process of embryo implantation by inhibiting motility of endometrial stromal cells through reducing c-kit expression
Published 2024“…</i> 56.1%, <i>p</i> < .001) in the GnRH-ant group were significantly decreased. Contrarily, the rate of early miscarriage in the GnRH-ant group (13.95% <i>vs.…”