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10201
Table 1_Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia.docx
Published 2025“…</p><p>Results: This study demonstrated that PCPs significantly mitigated body weight loss, restored muscle fiber atrophy and mitochondrial disorder, alleviated adipose tissue wasting, strengthened the intestinal barrier integrity, and decreased the intestinal inflammation in chemotherapy-induced cachexia. …”
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10202
Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx
Published 2025“…</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. Functional investigations demonstrated that IGFBP5 downregulation exacerbated PM-induced oxidative damage, as evidenced by elevated levels of reactive oxygen species (ROS) and malondialdehyde, as well as decreased levels of superoxide dismutase 2 (SOD2). …”
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10203
Table 6_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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10204
CONSORT Flowchart of Participants.
Published 2025“…To address obesity in adults with severe intellectual disabilities who are highly dependent, we developed the “Conflict-Free Weight Loss Program for Adults with Severe ID and Autism” to support their mothers and piloted the program, and the results showed that it was effective for weight loss. This study aimed to determine the feasibility of day center nurses and dieticians implementing the “Conflict-Free Weight Loss Program for Adults with Severe ID and Autism” and whether this would support effective weight loss in adults with severe intellectual disabilities, both with and without autism. …”
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10205
Data Sheet 1_MgSO4 alleviates hippocampal neuroinflammation and BBB damage to resist CMS-induced depression.docx
Published 2025“…Purpose<p>Magnesium sulfate (MgSO<sub>4</sub>) possesses the advantages of being readily accessible, cost-effective, and having low toxicity. It has potential applications as a neuroprotective agent. …”
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10206
Table 1_The association between dietary creatine intake and cancer in U.S. adults: insights from NHANES 2007–2018.docx
Published 2025“…Interaction results indicated specific age group effects. Further analysis showed that higher dietary creatine intake was significantly inversely associated with cancer risk among older adults (adjusted OR = 0.86, 95% CI: 0.77–0.97, p = 0.014). …”
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10207
Table1_Gut microbiota and metabolomics unveil the mechanisms of Lomatogonium rotatum in ameliorating visceral fat and serum lipids in high-fat diet-induced obese mice.XLSX
Published 2024“…Our study demonstrated that LR has lipid lowering and visceral fat reduction effects and its function may be closely related to the improvement of the gut microbiota and its associated metabolites.…”
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10208
Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste...
Published 2025“…This study investigates the long-term effects of 8 years of GM application combined with plow tillage on soil microbial communities and physicochemical properties under a peanut monocropping system. …”
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10209
Image 1_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg
Published 2025“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”
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10210
<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b>
Published 2025“…The 4-week AngII group exhibited significantly increased fibrosis (~2-fold vs. Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …”
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10211
Table 1_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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10212
Table 4_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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10213
Data Sheet 2_Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism.pdf
Published 2025“…This indicates that the proposed method for constructing a bilayer optimization configuration can effectively consider the economic consumption of new energy and significantly improve the economic operation of shared energy storage stations and regional microgrids.…”
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10214
<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b>
Published 2025“…Side effects were limited to benign gastrointestinal symptoms. …”
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10215
Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Antiviral and immunomodulatory effects were assessed by quantitative RT-PCR and analysis of inflammatory markers, including interferon-stimulated genes (MX1, IFI44L, IFN-β) and cytokines (IL-1β, TNF-α). …”
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10216
Table 3_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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10217
Image 2_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg
Published 2025“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”
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10218
Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Antiviral and immunomodulatory effects were assessed by quantitative RT-PCR and analysis of inflammatory markers, including interferon-stimulated genes (MX1, IFI44L, IFN-β) and cytokines (IL-1β, TNF-α). …”
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10219
Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Antiviral and immunomodulatory effects were assessed by quantitative RT-PCR and analysis of inflammatory markers, including interferon-stimulated genes (MX1, IFI44L, IFN-β) and cytokines (IL-1β, TNF-α). …”
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10220
A platform for the rapid screening of equine immunoglobins F (ab)2 derived from single equine memory B cells able to cross-neutralize to influenza virus
Published 2024“…Antibody H81 exhibited the highest cross neutralizing activities against EIV strains <i>in vitro</i>. Furthermore, it effectively protected EIV-challenged mice, resulting in significantly improved survival, reduced pulmonary inflammation and decreased viral titers. …”