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significant effects » significant effect (Expand Search), significantly affected (Expand Search)
effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
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18341
Image 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden...
Published 2025“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”
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18342
Table 5_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xls...
Published 2025“…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …”
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18343
Table_1_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.DOC
Published 2024“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”
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18344
Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies
Published 2025“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”
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18345
The impact of controlled release fertilizer on the growth and physiology of advanced seedlings of sour passion fruit
Published 2025“…The 4–8 kg m<sup>−3</sup> CRF dose resulted in a significant increase in seedling vigor 85 days after emergence stabilization. …”
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18346
Image 3_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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18347
Composition and Detailed Characterization of Amino Acids, Peptides, Proteins, Fatty Acids, and Minerals of Tuna Trimming Fish Meal
Published 2025“…Tuna processing byproducts hold significant nutritional value, though their quality can vary based on species, size, environment, and processing level. …”
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18348
Image 6_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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18349
Data Sheet 1_In vivo profiling of the PE/PPE proteins of Mycobacterium tuberculosis reveals diverse contributions to virulence.pdf
Published 2025“…In all, 27 of the 87 mutants showed significant reductions in percent population prevalence in the lung over 3 weeks. …”
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18350
Table 2_The global, regional, and national alcohol-related colorectal cancer burden and forecasted trends: results from the global burden of disease study 2021.csv
Published 2024“…From 1990 to 2021, the number of cases increased, but the Age-Standardized Rate (ASR) decreased. The trends in disease burden predicted by the two models for 2022–2046 were not consistent.…”
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18351
Table 11_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xl...
Published 2025“…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …”
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18352
Table 1_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx
Published 2025“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”
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18353
Image 7_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.jpeg
Published 2025“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”
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18354
Image 11_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
Published 2025“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”
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18355
Table 2_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden...
Published 2025“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”
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18356
Image 2_Computed tomography and magnetic resonance imaging features of primary liver perivascular epithelioid cell tumor with renal angiomyolipoma: a case report and literature rev...
Published 2025“…The enhancement slightly decreased in the equilibrium phase and the delayed phase. …”
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18357
Table 8_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
Published 2025“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”
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18358
Data_Sheet_3_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF
Published 2024“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”
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18359
DataSheet1_Two-decade variability and trend of chlorophyll-a in the Arabian Sea and Persian Gulf based on reconstructed satellite data.docx
Published 2024“…Trend analysis using Sen’s slope and the Mann-Kendall test indicates significant Chl-a declines (-0.002 to 0) along ASPG coasts, with slight increases (~0.005) in the southeastern AS and southern PG. …”
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18360
Table 2_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx
Published 2025“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”