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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant effects » significant effect (Expand Search), significantly affected (Expand Search)
effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
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9621
Data Sheet 9_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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9622
Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Alirocumab significantly improved spatial working memory, restored hippocampal long-term potentiation, and normalized synaptophysin expression. …”
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9623
Data Sheet 11_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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9624
Data Sheet 1_Stand structure influences understory plant diversity through soil factors: three afforestation types of Masson’s pine in the upper Yangtze River, China.docx
Published 2025“…In terms of stand structure, MCLMF significantly increased the opening degree (O), mingling index (M), and competition index (CI), while MLMF decreased CI but increased M. …”
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9625
<b>The Impact of Vitiligo on Pregnancy and Perinatal Outcome: A Systematic Review and Meta-analysis</b>
Published 2025“…This study followed MOOSE guidelines. A random-effects model was used to calculate the OR and 95% CI.…”
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9626
Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx
Published 2025“…After baicalein treatment, the proinflammatory cytokines (TNF-α, IL-1β), and anti-inflammatory cytokine (IL-10) has decreased. Additionally, high-dose of baicalein strongly reversed oxidative stress alterations caused by DSS, as evidenced by Fe<sup>2+</sup>, MDA, ROS significantly depleted, and MPO, SOD, GSH significantly increased. …”
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9627
DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx
Published 2025“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”
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9628
Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis
Published 2025“…<p>Betulinic acid (BA) is a pentacyclic triterpenoid with broad pharmacological potential and widely recognized for its neuroprotective effects. This study investigated the potential protective effects of this compound on <i>in vitro</i> differentiated human neuroblastoma SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, neuroinflammation, and dopaminergic cell death, and explored the underlying mechanisms. …”
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9629
Image 1_Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction.tif
Published 2025“…However, why visceral adipocytes show different effects on healthy and ageing cardiomyocytes is less known.…”
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9630
Data Sheet 1_Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction.pdf
Published 2025“…However, why visceral adipocytes show different effects on healthy and ageing cardiomyocytes is less known.…”
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9631
Image 2_Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction.tiff
Published 2025“…However, why visceral adipocytes show different effects on healthy and ageing cardiomyocytes is less known.…”
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9632
Data Sheet 1_Pseudomonas oryzihabitans D1-104/3 and P. gessardii C31-106/3 differentially modulate the antioxidative response of duckweed (Lemna minor L.) to salt stress.docx
Published 2024“…The doubling time of duckweeds inoculated with P. gessardii C31-106/3 was significantly longer. Additionally, at 0 and 10 mM NaCl, this strain decreased chlorosis in duckweeds. …”
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9633
DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf
Published 2024“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”
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9634
Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx
Published 2024“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”
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9635
Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx
Published 2025“…High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …”
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9636
Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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9637
Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx
Published 2025“…Background<p>Pregnancy significantly affects the maternal cardiovascular system, with physiological adaptations characterized by cardiac hypertrophy and increased capillarization. …”
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9638
Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis
Published 2025“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”
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9639
Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…Objective<p>To evaluate the effects and underlying mechanisms of resveratrol—a plant-derived polyphenol abundantly found in natural dietary sources such as grapes and blueberries—on the amelioration of liver fibrosis.…”
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9640
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function
Published 2025“…Roxadustat also remarkably decreased the expression of KIM-1 and NGAL. Furthermore, roxadustat significantly abolished the expression of Bax and cleaved caspase 3, two apoptosis marker proteins. …”