Table 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Table 4_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx حسب Pamela Mda (20390050)

"…Cox regression analysis was used to assess factors associated with incident pregnancy.</p>Results<p>There were 2,636 participants who received at least one vaccine or placebo dose (mean age: 23 years, standard deviation: 3 years). …"

Data Sheet 1_Investigation on the influence of structural surface characteristics on stress wave propagation behavior.docx حسب Pengxu Jing (20830229)

"…By monitoring key parameters such as permanent displacement, acceleration, and stress values of the stress waves, the influencing laws are revealed: When the stiffness of the structural planes exceeds a certain critical threshold (i.e., 2.8×10⁶ Pa), the permanent displacement, acceleration, and stress values of the stress waves significantly increase with increasing stiffness. The increase in structural plane spacing promotes significant growth in the permanent displacement, acceleration, and stress values of the stress waves, which is another key factor affecting the propagation characteristics of stress waves. …"

Data Sheet 1_Study on the changes in the temperature sensitivity of spring phenology of typical woody plants in the Qinling Mountains region.zip حسب Shanhong Zhang (12912707)

"…There was consistency between the plant phenological change and climate change in the Qinling Mountains region; that is, the year of the spring and autumn phenology change was basically the same as that of the climate change. (2) The temperature sensitivity of spring phenology showed a significant decreasing trend before the abrupt change but showed an insignificant increasing trend after the abrupt change. (3) The rate of change in spring temperature was the main factor affecting the change in temperature sensitivity of spring phenology. …"

Table_1_Efficacy of integrated traditional Chinese and western medicine in managing mild-moderate acute pancreatitis: a real-world clinical perspective analysis.docx حسب Sailei Jia (19966413)

"…</p>Results<p>Compared with the control group, the ITCWM group significantly decreased C-reactive protein (CRP, mg/L) (17.8 [1.2–59.5] vs. 8.0 [3.3–33.5], P = 0.022), shortened the duration of abdominal distension, abdominal pain, nausea and bitter taste symptoms (P < 0.05), and shortened the length of hospital stay (median 19.0 and 11.5 days, respectively, P = 0.001); Compared with the other two groups, the neutrophil percentage (NEUT%) was lower (74.1 vs. 61.9 vs. 59.5, P < 0.05) and serum prealbumin (PA, mg/L) was higher (116.0 vs. 184.4 vs. 220.0, P < 0.05), the length of hospitalization (days) was shortened (19.0 vs.12.0 vs.10.0, P < 0.05) in the OCM+E group.…"

Table_1_Efficacy of integrated traditional Chinese and western medicine in managing mild-moderate acute pancreatitis: a real-world clinical perspective analysis.docx حسب Sailei Jia (19966413)

"…</p>Results<p>Compared with the control group, the ITCWM group significantly decreased C-reactive protein (CRP, mg/L) (17.8 [1.2–59.5] vs. 8.0 [3.3–33.5], P = 0.022), shortened the duration of abdominal distension, abdominal pain, nausea and bitter taste symptoms (P < 0.05), and shortened the length of hospital stay (median 19.0 and 11.5 days, respectively, P = 0.001); Compared with the other two groups, the neutrophil percentage (NEUT%) was lower (74.1 vs. 61.9 vs. 59.5, P < 0.05) and serum prealbumin (PA, mg/L) was higher (116.0 vs. 184.4 vs. 220.0, P < 0.05), the length of hospitalization (days) was shortened (19.0 vs.12.0 vs.10.0, P < 0.05) in the OCM+E group.…"

Supplementary file 1_The impact of COVID-19 on thyroid function and psychological state of Graves’ disease: a one-year prospective study.jpeg حسب Lujia Xu (6912416)

"…At 1 year post-infection, TSH levels in the G1 and G3 groups increased compared to 3 months, while psychological scores decreased. The G3 group had significantly higher TSH levels than pre-infection, with significant intergroup differences in FT3 and FT4 levels.…"

Supplementary file 2_The impact of COVID-19 on thyroid function and psychological state of Graves’ disease: a one-year prospective study.jpeg حسب Lujia Xu (6912416)

"…At 1 year post-infection, TSH levels in the G1 and G3 groups increased compared to 3 months, while psychological scores decreased. The G3 group had significantly higher TSH levels than pre-infection, with significant intergroup differences in FT3 and FT4 levels.…"

Data Sheet 1_Mechanisms of c-Fos regulation of mTOR signaling via ERα/β in abnormal lipid metabolism of granulosa cells in PCOS.pdf حسب Xinyi Chen (491760)

"…In PCOS patients, c-Fos and p-mTOR/mTOR protein levels were higher than in male factor infertility patients, while ERα levels were lower, with no significant difference in ERβ expression between the two groups. …"

Table 1_A study of the adjunctive therapeutic effects of a 3-week bamboo forest therapy on chronic diseases in the elderly.docx حسب Jing He (58446)

"…Diabetic participants showed significant decreases in fasting and pre-bedtime blood glucose levels (p < 0.001), along with reduced blood glucose fluctuations post-meal. …"

Table 1_Variations in vitamin D status among Chinese children aged 1–6 years during the COVID-19 pandemic.xlsx حسب Yongfeng Qiao (3354326)

"…The average of 25(OH)D concentration were 38.2 ± 9.8 ng/ml, significantly varying by age and season. 25(OH)D concentrations decreased with age, from 42.3 ± 8.8 ng/ml at 1-year-olds to 37.4 ± 8.2 ng/ml at 2-year-olds, and further to 30.2 ± 8.1 ng/ml at 3 to 6-year-olds. …"

Supplementary file 1_Analysis of the diagnostic value of peripheral blood immune inflammatory indicators of female bladder pain syndrome.zip حسب Yinglei Wang (3844756)

"…Multivariate binary logistic regression analysis revealed decreased PLT as an independent risk factor for reduced bladder capacity.…"

Data Sheet 2_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf حسب Samira Rastgoo (15252703)

"…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …"

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"