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4701
Data Sheet 1_Effects of different fermentation temperatures on microbiomes of cigar tobacco leaves.pdf
Published 2025“…Introduction<p>Microbiomes of cigar tobacco leaves play a pivotal role during the fermentation, and fermentation temperature is a key factor in shaping the structure and function of the microbial community. …”
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4702
Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC
Published 2025“…<p>To investigate the susceptibility of Runt-related transcription factor 1 (RUNX1) promoter polymorphism to adjuvant chemotherapy-induced neutropenia (CIN) of colorectal cancer (CRC).…”
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4703
Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel
Published 2025“…Notably, expression of <i>PacC</i>, a pH-responsive transcription factor critical for virulence, was downregulated in hyphal bodies of the Δ<i>Mrgdh2</i> mutant. …”
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4704
Table1_CD34 evaluation of microvasculature in lung adenocarcinoma and its microvascular density predicts postoperative tumor recurrence.xlsx
Published 2025“…Thus, the detection of intratumoral MVD is of great significance for understanding disease progression and predicting patient prognosis.…”
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4705
Data_Sheet_1_MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.pdf
Published 2024“…Through deletion mutant analysis, we found that individual deletions of makC or makD do not significantly affect MakA expression or secretion. However, the deletion of both makC and makD impairs the expression of MakB, which is directly downstream, and decreases the expression of MakE, which is separated from makCD by two genes. …”
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4706
Data Sheet 1_Beta-amyloid influences the content and trafficking of beta-amyloid precursor protein via Na,K-ATPase-Src kinase positive feedback loop.pdf
Published 2025“…Furthermore, 100 nM CTS ouabain, a specific Na,K-ATPase ligand, significantly decreased Aβ′s impact on APP and Src kinase activation. …”
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4707
Image 1_REDD1 attenuates cholestatic liver fibrosis and suppresses PI3K/AKT/mTOR pathway.jpg
Published 2025“…Cholestasis is an important factor causing liver fibrosis. However, there are currently no effective anti-fibrotic drugs for cholestatic liver fibrosis in clinical practice.…”
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4708
Data Sheet 1_Coordinated development of ecosystem services and human well-being is increasing in the Yellow River Basin, though some regions lag behind.docx
Published 2025“…Initially, we estimated ecosystem services value (ESV) for each province in the YRB using the revised equivalent factor method, and evaluated the level of HWB by GRA-TOPSIS model. …”
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4709
Data Sheet 1_Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae.pdf
Published 2025“…Infections of Galleria mellonella larvae showed a significantly decreased virulence potential of the CPS-deficient mutant.…”
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4710
Vitreous Olink Proteomics Uncovers Novel Inflammatory Proteins in Patients with Proliferative Diabetic Retinopathy
Published 2025“…Key findings revealed 22 differentially expressed proteins (DEPs) when comparing the PDR and IMH groups, with 21 proteins showing increased expression and only one demonstrating decreased levels. Among these DEPs, fibroblast growth factor 23 (FGF23) emerged as a particularly promising candidate, as elevated expression was observed in retinal tissue from both diabetic (db/db) mice and the high-glucose (HG) or glyoxal-treated Müller glia (MG) cultures. …”
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4711
Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf
Published 2025“…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …”
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4712
Data Sheet 1_The prevalence and antimicrobial resistance of respiratory pathogens isolated from feedlot cattle in Canada.zip
Published 2025“…Objectives<p>The purpose of this study was to characterize the prevalence of antimicrobial resistance in Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni isolated from healthy feedlot cattle over 2 years, and investigate factors potentially associated with recovery of resistant isolates.…”
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4713
Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx
Published 2025“…We evaluated CAVI and its associated factors in 590 children aged 6–15 years (mean age: 10.5 years, 51.0% female). …”
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4714
Supplementary file 1_Effects of different urban vegetation cover and green space types on soil greenhouse gas emissions and carbon sequestration.docx
Published 2025“…The annual increase of SOC in residential and streets was notably lower than that in parks green spaces, by 9.59% and 15.20%, respectively, indicating significant differences. This suggests that soil carbon sequestration capacity is highly responsive to changes in vegetation coverage and green space types, with WSOC, NH<sub>4</sub><sup>+</sup>-N, and pH identified as the primary factors influencing the greenhouse gas flux in the three soils. …”
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4715
Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx
Published 2025“…Background<p>Both recent negative life events (RNLEs) and lifestyle factors were associated with depressive symptoms, but it is unclear whether adopting a healthy lifestyle can mitigate the association between RNLEs and depressive symptoms. …”
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4716
Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf
Published 2025“…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …”
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4717
Data Sheet 1_Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.zip
Published 2025“…The impact of influencing factors on irAEs (immune-related adverse events) was validated using Decision Curve Analysis (DCA). …”
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4718
Image 1_Multi-omics analysis reveals indicator features of microbe-host interactions during Candida albicans colonization and subsequent infection.tif
Published 2024“…</p>Methods<p>We explored risk factors associated with C. albicans GI colonization and ensuing translocated infection. …”
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4719
Data Sheet 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatic...
Published 2025“…Background<p>Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). …”
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4720
Table 3_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
Published 2025“…Background<p>Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). …”