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17961
Data Sheet 1_Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database.docx
Published 2025“…</p>Conclusion<p>While tolvaptan provides therapeutic benefits, it poses a risk of significant adverse reactions. Clinicians should closely monitor the occurrence of events related to hepatobiliary disorders, renal and urinary disorders, metabolic and nutritional disorders, as well as benign, malignant, and indeterminate tumors during its clinical use.…”
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17962
Effects of task optimization on pareidolia representations in CNNs.
Published 2025“…Conversely, in CNNs lacking object categorization training (Panels B, C), this similarity was weak, only reaching significance at early layers, and decreased across layers. …”
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17963
Table 3_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
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17964
DataSheet2_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf
Published 2024“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”
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17965
Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx
Published 2025“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”
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17966
Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr...
Published 2024“…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …”
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17967
Supplementary file 1_Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms.docx
Published 2025“…<p>Mechanical strain plays a significant role in lung pathophysiology. Current two-dimensional (2D) in vitro models fail to capture the lung's dynamic mechanical environment. …”
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17968
Image2_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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17969
Table2_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.xlsx
Published 2024“…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …”
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17970
Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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17971
Table 3_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.xlsx
Published 2025“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”
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17972
Image 3_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg
Published 2025“…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”
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17973
Supplementary file 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx
Published 2025“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”
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17974
Divergent gene expression in <i>D. sechellia.</i>
Published 2025“…<p><b>(A)</b> Histogram of the frequency of <i>D. sechellia</i>-specific DEGs across 94 cell types, arranged by decreasing DEG number. The remaining 13 cell types with no DEGs are not shown. …”
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17975
Amplifying key words’ intensity promotes memory (Liu et al., 2025)
Published 2025“…Heart rate and skin conductance level of the subjects decreased with amplification of key word intensity in the 9-dB group, which indicated that this promoted the memory effect by enhancing attention.…”
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17976
Data Sheet 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.docx
Published 2025“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”
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17977
Data Sheet 1_Efficacy of different pharmaceutical forms of Curcuma longa or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and m...
Published 2025“…The pooled analysis showed significant reductions in WHO scores and oral pain compared to placebo. …”
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17978
Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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17979
Exploring the dynamics of gut microbiota, antibiotic resistance, and chemotherapy impact in acute leukemia patients: A comprehensive metagenomic analysis
Published 2024“…<p>Leukemia poses significant challenges to its treatment, and understanding its complex pathogenesis is crucial. …”
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17980
Table_3_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.DOCX
Published 2025“…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …”