Data Sheet 3_N6-methyladenosine RNA landscape in the aged mouse hearts.zip حسب Xia Jing (3255219)

"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"

Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf حسب Xia Jing (3255219)

"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"

Data Sheet 1_Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and athe... حسب Fan Xie (562816)

"…</p>Conclusion<p>The use of STS in patients with AS and ASCVD appeared to significantly decrease levels of pro-inflammatory cytokines, adhesion molecules, and chemokines.…"

Data Sheet 1_ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway.docx حسب Xiaofei Huang (2262337)

"…Moreover, it suppressed conventional CD4⁺CD25^- T cell proliferation in vitro in the absence of antigen-presenting cells (APCs), with an increase in IL-10 and decrease in IFN-γ production. On the other hand, it did not significantly alter DC maturation after allotransplantation.…"

Data Sheet 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.docx حسب Chang Liu (35901)

"…Secondary outcomes focused on molecular markers such as brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), and indicators of oxidative stress. …"

Table 2_Associations between physical fitness components and metabolic syndrome in middle-aged adults: a cross-sectional study using relative strength indicators and ROC analysis.d... حسب Zhanfei Zheng (22629227)

"…Introduction<p>Metabolic syndrome (MetS) is a major risk factor for cardiovascular disease (CVD) and type 2 diabetes, particularly in middle-aged populations. …"

Image 2_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif حسب Chang Liu (35901)

"…Secondary outcomes focused on molecular markers such as brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), and indicators of oxidative stress. …"

Supplementary file 1_The efficacy and safety of Fuzheng traditional Chinese medicine injections in the treatment of acute ischemic stroke: a systematic review and network meta-anal... حسب Qiaosheng Ren (20532449)

"…The treatment that was most likely to be the best in terms of the high-cut viscosity of whole blood (HCV) was SHM + CT. Considering the decrease in the tumor necrosis factor-α (TNF-α) level, SM + CT had the best chance of being the best treatment.…"

Table 1_Associations between physical fitness components and metabolic syndrome in middle-aged adults: a cross-sectional study using relative strength indicators and ROC analysis.d... حسب Zhanfei Zheng (22629227)

"…Introduction<p>Metabolic syndrome (MetS) is a major risk factor for cardiovascular disease (CVD) and type 2 diabetes, particularly in middle-aged populations. …"

Image 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif حسب Chang Liu (35901)

"…Secondary outcomes focused on molecular markers such as brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), and indicators of oxidative stress. …"

Supplementary Material for: Treatment of plaque psoriasis with guselkumab reduces systemic inflammatory burden as measured by neutrophil/lymphocyte ratio, platelet/lymphocyte ratio... حسب figshare admin karger (2628495)

"…In VOYAGE I, NLR (p=0.011), PLR (p=0.015) and MLR (p=0.004) decreased significantly following 16 weeks of guselkumab treatment vs. placebo. …"

Supporting information_Soil carbon isotopes in global coastal wetlands حسب Qian Hao (15288697)

"…The results indicated that soil δ¹³C exhibits significant spatial heterogeneity across global coastal wetlands, with values ranging from -21.20‰ to -9.00‰ and decreasing with increasing latitude. …"

Data Sheet 1_The global, regional, and national impact of laryngeal cancer from 1990 to 2021, along with forecasts for 2050: a comprehensive analysis for the Global Burden of Disea... حسب Tingting Duan (5181482)

"…Smoking and excessive alcohol consumption are the main risk factors for LC.</p>Conclusions<p>While the global LC burden has moderated, significant disparities persist across SDI regions. …"

<b>Exploring left lateral decubitus position, and its influence on infant mortality in pregnant women in their third trimester, brought to the emergency through the GVK Ambulance S... حسب Laggy George (19873020)

"…</p><p dir="ltr">Conclusion:</p><p dir="ltr">Transporting mothers in a Left Lateral Decubitus position may significantly decrease the odds of Infant mortality by 62%; after adjusting for antenatal care visits. …"

Image 1_Continuous watermelon cropping impairs plant growth by modifying soil biochemistry and rhizosphere microbial communities.tif حسب HuiFang Lv (22222615)

"…We investigated the impact of continuous watermelon cropping on soil biochemical properties, enzyme activities, microbial biomass, occurrence of Fusarium wilt, diversity and structure of bacterial and fungal communities, as well as the relationship among these factors with plant growth. The results showed significant decreases in soil pH, OM, AN, AP, and AK contents (p < 0.05), while UA, APA, and DA were reduced, along with declines in MBC and MBN in the rhizosphere soil of continuous watermelon cropping (p < 0.05). …"

Image 2_Continuous watermelon cropping impairs plant growth by modifying soil biochemistry and rhizosphere microbial communities.tif حسب HuiFang Lv (22222615)

"…We investigated the impact of continuous watermelon cropping on soil biochemical properties, enzyme activities, microbial biomass, occurrence of Fusarium wilt, diversity and structure of bacterial and fungal communities, as well as the relationship among these factors with plant growth. The results showed significant decreases in soil pH, OM, AN, AP, and AK contents (p < 0.05), while UA, APA, and DA were reduced, along with declines in MBC and MBN in the rhizosphere soil of continuous watermelon cropping (p < 0.05). …"

Data Sheet 1_Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.docx حسب Yiting Tang (2295307)

"…This study aims to comprehensively quantify the global burden of T2DM attributable to dietary risks among elderly adults, identify significant dietary risk factors driving disease burden, and evaluate temporal, regional, and demographic variations to inform targeted public health strategies and interventions for reducing the impact of T2DM.…"

Image 1_The efficacy of sequentially comprehensive treatment based on surgery in the treatment of keloids: a retrospective study.jpeg حسب Kun Yang (19445)

"…The clinical response rate of tumor-type keloids (95.8%) was higher than that of inflammatory-type (70.0%) with a significant difference (P = 0.040). After treatment, the color, blood vessel distribution, softness, thickness, and VSS score were all decreased, and the difference was statistically significant (P < 0.001).…"

An empirical analysis of overeducation among master's graduates in Spain حسب Martín Martín-González (22251135)

"…<p>This study investigates the factors influencing overeducation among graduates in Spain, a phenomenon with significant implications such as reduced wages, lower productivity, and decreased job satisfaction. …"

Table 1_Unveiling neuroimmunology profile of immunological non-responders in HIV: a multimodal MRI approach.docx حسب Yang Zhang (30734)

"…Mass cytometry and Luminex/ELISA assays were employed to analyze peripheral blood monocytes, T cell subpopulations, cytokines, chemokines, neurotrophic factors, and endocrine factors.</p>Results<p>Neuroimaging findings revealed notable changes in brain structure and function in INRs, including increased fractional amplitude of low-frequency fluctuations and regional homogeneity in the left middle temporal gyrus, as well as decreased grey matter volume in the left middle temporal gyrus, left lingual gyrus, and right rolandic operculum. …"