Data Sheet 1_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip حسب Siqi Ye (9350531)

"…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …"

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip حسب Dongmei Yuan (291583)

"…The results revealed a decreased abundance of phospholipids such as phosphatidylethanolamine (PE) and phosphatidylcholine (PC) and an increased abundance of their metabolites, including lysophosphatidylcholine (LPC), lysophosphatidylethanolamine (LPE), lysophosphatidylserine (LPS), and platelet-activating factor (PAF). …"

<i>Neisseria</i> species on the tonsillar surface predicts favorable clinical outcomes in patients with Immunoglobulin A nephropathy who underwent tonsillectomy حسب Ryosuke Sato (615801)

"…The Cox proportional hazards model indicated the presence of <i>Neisseria</i> sp. on the tonsillar surface as an independent favorable factor for the rates of clinical remission, decreasing renal function, and renal death (hazard ratios: 3.42, 0.03, and 0.06, respectively). …"

Supplementary Material for: Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis حسب figshare admin karger (2628495)

"…RNA sequencing identified 905 DEGs in IgAN patients, with significant enrichment in neutrophil and NETosis pathways. …"

Image 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.pdf حسب Xu Zheng (296676)

"…</p>Results<p>From 1990 to 2021, the incidence rate and YLDs rate of hip dislocation decreased, while the number of cases and YLDs number increased. …"

Image 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.tif حسب Xu Zheng (296676)

"…</p>Results<p>From 1990 to 2021, the incidence rate and YLDs rate of hip dislocation decreased, while the number of cases and YLDs number increased. …"

Table 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx حسب Xu Zheng (296676)

"…</p>Results<p>From 1990 to 2021, the incidence rate and YLDs rate of hip dislocation decreased, while the number of cases and YLDs number increased. …"

Table 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx حسب Xu Zheng (296676)

"…</p>Results<p>From 1990 to 2021, the incidence rate and YLDs rate of hip dislocation decreased, while the number of cases and YLDs number increased. …"

Supplementary Material for: Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration حسب Rouse M. (20413172)

"…Five of 55 protein analytes that were up-regulated 1.4-120X at ICU admission relative to healthy controls showed significant decreases across the filter during the indicated time points on the first day of hemoperfusion: IP-10/CXCL10, fms-like tyrosine kinase (Flt-1), MIG/CXCL9, Hepatocyte Growth Factor (HGF) and receptor for advanced glycosylation end-products (RAGE). …"

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Table_1_Psychological wellbeing among carers of children and adolescents with physical disabilities in North-Eastern Tanzania—a cross-sectional survey study.docx حسب Elia Asanterabi Swai (15337336)

"…Notably, poor psychological wellbeing was significantly associated with symptoms of anxiety and depression. …"

Data_Sheet_1_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV حسب Ming-Jie Jia (18267391)

"…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …"

Data_Sheet_2_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV حسب Ming-Jie Jia (18267391)

"…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …"

Data Sheet 2_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.zip حسب Han-han He (20594477)

"…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …"

Data Sheet 1_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.zip حسب Han-han He (20594477)

"…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …"