Data Sheet 1_GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells.pdf by Fumiya Ito (14833366)

“…GRHL2 was upregulated in ER cells, and its knockdown and knockout significantly reduced erlotinib resistance. Further analysis revealed that GRHL2 upregulates the receptor tyrosine kinase HER3, and that HER3 knockdown similarly decreases the IC₅₀ for erlotinib. …”

DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx by Rocío Rubio (513839)

“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”

Efficient Optimization of Plasma Radiation Detector Configurations using Imperfect Inference Models by Difan Song (15209755)

“…The method allows us to find detector configurations that perform similarly to or better than the configuration obtained using an existing sampling-based optimization method while decreasing computational time by a factor of 50.</p>…”

Image_1_Mechanical acupuncture at HT7 attenuates alcohol self-administration in rats by modulating neuroinflammation and altering mPFC-habenula-VTA circuit activity.TIF by Su Yeon Seo (4967656)

“…</p>Results<p>Our findings demonstrate that stimulation of the HT7 acupuncture point significantly decreased the frequency of active lever presses in rats self-administering alcohol (p < 0.05). …”

Image_2_Mechanical acupuncture at HT7 attenuates alcohol self-administration in rats by modulating neuroinflammation and altering mPFC-habenula-VTA circuit activity.TIF by Su Yeon Seo (4967656)

“…</p>Results<p>Our findings demonstrate that stimulation of the HT7 acupuncture point significantly decreased the frequency of active lever presses in rats self-administering alcohol (p < 0.05). …”

Supplementary file 2_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx by Guixin He (2547469)

“…</p>Results<p>Analysis results showed that multivariate logistic regression identified increasing age, increased absolute counts (AC) of CD4+CD38−T cells, and decreased AC of CD4+CD28−T cells as independent risk factors for CRF (P < 0.05). …”

<b>IMPACT OF MULTIVITAMINS AND PROCESSED MEAT ON AGING: A MACHINE LEARNING APPROACH</b> by Mohcene M. (20142864)

“…<p dir="ltr">Aging is a complex process influenced by numerous factors, including dietary habits. Processed meat consumption has been associated with accelerated aging and increased risk of age-related diseases. …”

Supplementary file 1_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx by Guixin He (2547469)

“…</p>Results<p>Analysis results showed that multivariate logistic regression identified increasing age, increased absolute counts (AC) of CD4+CD38−T cells, and decreased AC of CD4+CD28−T cells as independent risk factors for CRF (P < 0.05). …”

Data Sheet 1_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... by Ettore Silvagni (9576002)

“…Objective<p>The aim of this study was to comparatively assess the risk of cardiovascular events (CVEs) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis) or tumor necrosis factor inhibitors (TNFis) and to explore the interactions with patient profiles [including age, baseline cardiovascular (CV) risk, and frailty, which is a state of decreased physiological reserve, assessed using a validated frailty index (FI) for healthcare administrative databases (AHDs)].…”

Data Sheet 2_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... by Ettore Silvagni (9576002)

“…Objective<p>The aim of this study was to comparatively assess the risk of cardiovascular events (CVEs) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis) or tumor necrosis factor inhibitors (TNFis) and to explore the interactions with patient profiles [including age, baseline cardiovascular (CV) risk, and frailty, which is a state of decreased physiological reserve, assessed using a validated frailty index (FI) for healthcare administrative databases (AHDs)].…”

Data Sheet 1_Psychological Well-Being in Adults Across the COVID-19 Pandemic: A Two-Year Longitudinal Study.docx by Melanie Ehrler (9759152)

“…Decreasing or consistently low well-being was significantly associated with younger age, limited social support, caregiving responsibilities, concerns about COVID-19 infection, and stress due to pandemic-related changes.…”

Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx by Vanessa I. T. Zwaans (22163257)

“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”

<i>mig-21</i> sensitizes adult DTCs to polarizing signals. by Xin Li (51274)

“…A robust “extra turn” defect rate of control on <i>vab-3</i> RNAi (n=38/57) decreases with <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=24/65), p < 0.01. …”

SLMO is required for the proper function of PISD. by Siwen Zhao (543384)

“…<p>(A) Schematic of the genome-wide RNAi screen for factors that prevent the rescue effects of PISD on the ERG defects of <i>pect</i>^<i>RNAi</i>. …”

<b>Morin alleviates fructose-driven disturbance of podocyte mitochondrial energy metabolism by inhibiting AMPD activity to improve glomerular injury</b> by Luyi Huang (22583081)

“…<p dir="ltr">High consumption of fructose is a significant risk factor for glomerular podocyte injury. …”

Ambient Air Pollutant Dynamics (2010–2025) and the Exceptional Winter 2016–17 Pollution Episode: Implications for a Uranium/Arsenic Exposure Event by Thomas Clemens Carmine (19756929)

“…</li><li><b>Long-Term Trends:</b> The complete time series reveals significant downward trends in NO₂, EC, and SO₂ over the ~15-year period. …”

Table 1_Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia.docx by Yufei Wu (3625967)

“…Univariate and multiple linear regression analyses explored the associations between perfusion and risk factors.</p>Results<p>The inner ring retinal vessel density and CVI in all areas were significantly different between groups (P < 0.05); CPV was not significantly changed except for the inferotemporal area among the groups. …”

Data Sheet 1_Splenic compensation alleviates impaired-development of bone marrow terminal erythroid to attenuate anemia in ATPIF1 knockout mice.docx by Jing Feng (177843)

“…<p>ATPIF1 (ATPase Inhibitory Factor 1) is a critical regulatory factor of mitochondrial ATP synthase, maintaining ATP homeostasis by modulating ATP synthesis and hydrolysis. …”

Table_1_Association between phthalates exposure and non-alcoholic fatty liver disease under different diagnostic criteria: a cross-sectional study based on NHANES 2017 to 2018.pdf by Jiazhen Zou (19739203)

“…Adjusting for all covariates in multivariate logistic regression, only MCiOP (OR = 4.22, 95% CI = 1.10–16.2, p = 0.044), as an oxidative metabolite of DINP, remained significantly associated with NAFLD under the VCTE criterion, suggesting its potential role as a risk factor for NAFLD.…”

Table_3_Association between phthalates exposure and non-alcoholic fatty liver disease under different diagnostic criteria: a cross-sectional study based on NHANES 2017 to 2018.pdf by Jiazhen Zou (19739203)

“…Adjusting for all covariates in multivariate logistic regression, only MCiOP (OR = 4.22, 95% CI = 1.10–16.2, p = 0.044), as an oxidative metabolite of DINP, remained significantly associated with NAFLD under the VCTE criterion, suggesting its potential role as a risk factor for NAFLD.…”