يعرض 5,381 - 5,400 نتائج من 5,404 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant factors decrease ))~', وقت الاستعلام: 0.45s تنقيح النتائج
  1. 5381

    Data Sheet 1_Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression.pdf حسب Wenjun Sui (22776290)

    منشور في 2025
    "…This study aims to investigate the effect of ADP-ribosylation factor-like 13B (ARL13B) on RPE EMT in PVR.</p>Methods<p>The expression of ARL13B in PVR specimens was analyzed by immunofluorescence (IF) staining. …"
  2. 5382

    Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf حسب Juanjuan Zhang (432819)

    منشور في 2025
    "…We evaluated disease activity index (DAI), colonic inflammation, and the expression of inflammatory mediators, peroxisome proliferator-activated receptor gamma (PPAR-γ) and forkhead box transcription factor O1 (FOXO1). </p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. …"
  3. 5383

    Data Sheet 1_Characterization of the Vibrio anguillarum VaRyhB regulon and role in pathogenesis.docx حسب Yingjie Li (2106778)

    منشور في 2025
    "…</p>Results<p>The small RNA called VaRyhB identified in V. anguillarum strain 775 is significantly longer than that in Escherichia coli. Transcriptomic analysis revealed that VaRyhB is critical for iron homeostasis under limited iron conditions, and deletion of VaRyhB resulted in lower expression levels of certain genes for siderophore biosynthesis and transport, thereby leading to impaired growth, reduced siderophore production, and decreased pathogenesis. …"
  4. 5384

    Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis حسب Chenyu Luo (12443535)

    منشور في 2025
    "…Additionally, low mechanics significantly diminishes NCOA4, pivotal in mediating FTH1 phase separation-induced ferritinophagy. …"
  5. 5385

    Table_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.docx حسب György Szklenarik (20296893)

    منشور في 2024
    "…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"
  6. 5386

    Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX حسب György Szklenarik (20296893)

    منشور في 2024
    "…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"
  7. 5387

    Table 1_High-concentrate diet supplemented with hydrolysable tannin improves the slaughter performance, intestinal antioxidant ability and barrier function of fattening lambs.docx حسب Jian Ma (170138)

    منشور في 2024
    "…The jejunum and ileum of TA1 lambs showed reduced (p < 0.05) tumor necrosis factor-alpha and increased (p < 0.05) interleukin-10 mRNA levels compared with CON lambs. …"
  8. 5388

    Table 1_Oral bacterial community dynamics during induction of gingival inflammation.xlsx حسب Bart J. F. Keijser (16884185)

    منشور في 2025
    "…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"
  9. 5389

    Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif حسب Yang Jing (2231179)

    منشور في 2025
    "…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …"
  10. 5390

    Data Sheet 1_The effect of establishment method and shade zones within solar arrays on pasture production in agrivoltaics production system.docx حسب Azad Dazaea (22173454)

    منشور في 2025
    "…However, herbage production did not differ significantly among establishment methods in either 2020/21 (p = 0.10) or 2021/22 (p = 0.17). …"
  11. 5391

    Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx حسب Bart J. F. Keijser (16884185)

    منشور في 2025
    "…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"
  12. 5392

    <i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation حسب jin guan (21792620)

    منشور في 2025
    "…Invasive strains exhibited significantly enhanced serum resistance (>17-fold survival in 75% isolates) and HeLa cell invasive ability (minimum bacterial loads 3.93 × 10⁵ CFU/mL) compared to non-invasive strains (< 9.8-fold survival; maximum bacterial loads 1.47 × 10⁵ CFU/mL). …"
  13. 5393

    List of primers used in quantitative RT-PCR. حسب Tarek A. Essa (22430744)

    منشور في 2025
    "…The results demonstrated that NPs significantly reduced basal rot symptoms and decreased the Area Under the Disease Progress Curve (AUDPC) values. …"
  14. 5394

    Table1_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…Chip-qPCR was employed to further elucidate the binding sites of the transcription factor c-Jun.</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. …"
  15. 5395

    Image 1_Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation.tif حسب Jingyi Hou (698975)

    منشور في 2025
    "…</p>Results<p>MitoDEGs in the MI group were significantly enriched in pathways related to mitochondrial transport and gene expression. …"
  16. 5396

    Table2_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…Chip-qPCR was employed to further elucidate the binding sites of the transcription factor c-Jun.</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. …"
  17. 5397

    Table3_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…Chip-qPCR was employed to further elucidate the binding sites of the transcription factor c-Jun.</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. …"
  18. 5398

    Presentation 1_Efficacy of disitamab vedotin in non-small cell lung cancer with HER2 alterations: a multicenter, retrospective real-world study.pdf حسب Meiling Zhang (352540)

    منشور في 2024
    "…Background<p>Non-small cell lung cancer (NSCLC) with human epidermal growth factor receptor 2 (HER2) alterations poses a substantial treatment challenge. …"
  19. 5399

    Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx حسب Yajie Hu (550783)

    منشور في 2024
    "…IFN-γ-inducible protein-10 (IP-10) is often used as a predictive factor to monitor early virus infection. It has also been reported that IP-10 plays a pivotal role in neuroinflammation. …"
  20. 5400

    Data Sheet 1_Environmental surveillance of the health risk of PM2.5-bound metals and metalloids in Wuxi, China, from 2020 to 2023.docx حسب Lijun Chen (313408)

    منشور في 2025
    "…The result of enrichment factor (EF) suggested most elements mainly derived from anthropogenic pollution, while industrial emissions (32.4%), automotive emissions (27.9%), fuel combustion (26.2%) and dust emissions (13.5%) identified as the main sources by the positive matrix factorization (PMF). …"