Short-Ranged United-Atom Model for Efficient Simulations of Glycerol and Its Aqueous Mixtures by Prabir Khatua (1738339)

“…While AA simulations are widely used, they overestimate the α-conformation and incur significant computational costs. Coarse-grained (CG) models provide an efficient alternative but have yet to accurately describe glycerol’s conformational distribution and thermodynamic behavior. …”

Effects of T5-1 and T5-12 on TAS2R5 expression during protein synthesis inhibition. by Donghwa Kim (252081)

Ydj1 acetylation alters interactions with client proteins. by Siddhi Omkar (12413434)

“…Interactors are colored according to change in interaction as follows: green (significant increase), red (significant decrease), or purple (no significant change) 6KQ/6KR. …”

Ydj1 acetylation impacts multiple aspects of translation. by Siddhi Omkar (12413434)

Single-phage therapy succeeds against phage resistance with a strong enough immune system. by Jacopo Marchi (7252499)

Colocalization results. by Marie C. Sadler (9649799)

“…Analyzing country-level allele frequencies and zinc deficiency prevalences revealed a 3-fold higher genetic zinc excretion risk in sub-Saharan Africa compared to Europe, significantly correlating with nutritional zinc deficiency prevalence. …”

Finemapping results. by Marie C. Sadler (9649799)

“…Analyzing country-level allele frequencies and zinc deficiency prevalences revealed a 3-fold higher genetic zinc excretion risk in sub-Saharan Africa compared to Europe, significantly correlating with nutritional zinc deficiency prevalence. …”

List of RT-qPCR primers. by Marie C. Sadler (9649799)

“…Analyzing country-level allele frequencies and zinc deficiency prevalences revealed a 3-fold higher genetic zinc excretion risk in sub-Saharan Africa compared to Europe, significantly correlating with nutritional zinc deficiency prevalence. …”

C2CD3 regulates spatial organization of centriole architecture. by Eloïse Bertiaux (5309927)

C2CD3 is crucial for the localization of the LDR and DISCO complexes. by Eloïse Bertiaux (5309927)

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Differences in pTSS profiles between pre- and full-term pregnancies. by Zhiwei Guo (335819)

Predicted chronic activation of the cardiomyocyte signaling network during VO. by Johane H. Bracamonte (12883844)

MDSC inhibition was correlated with Trp metabolism in 17ZR101-infected lungs. by Qi Xu (134661)

“…Fold change > 1.2 and FDR-adjusted P-value < 0.05 considered significant. …”

Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

RT-qPCR data tables. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

Key biological processes and genes are identified in TGF-β1-induced fibrosis via transcriptome analysis. by Dong-Hee Han (140305)

“…<b>(A)</b> Differentially expressed genes (DEGs; ≥2 folds, ≥7 normalized data value) significantly altered by TGF-β1 treatment were depicted by a Venn diagram. …”

Changes in volume, mass, and end-diastolic strain during experimental MR in dogs. by Johane H. Bracamonte (12883844)