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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant genes » significant gender (Expand Search), significant benefits (Expand Search), significant changes (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
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18761
Data Sheet 3_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18762
Table 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.xls
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18763
Image 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.jpeg
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18764
Data Sheet 5_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18765
Data Sheet 2_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18766
Data Sheet 8_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18767
Data Sheet 6_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18768
Data Sheet 7_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18769
Data Sheet 4_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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18770
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
Published 2025“…</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18771
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18772
Table 2_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18773
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18774
SEAwise Report on improved predictive models of recruitment under different habitat scenarios and incorporating experimental results
Published 2025“…Recruitment of Western Baltic cod and herring showed decreasing reproductive potential as temperature increased.…”
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18775
Data Sheet 1_Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage po...
Published 2025“…Furthermore, reducing cellular LXN/Rps3/p53 signaling significantly decreased SASP factors in the culture medium and simultaneously abolished M1-like phenotype macrophage polarization. …”
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18776
Data Sheet 1_Higher soil nitrous oxide production in landscape depressions linked to soil and hydrological legacy effects.docx
Published 2025“…Depression soils exhibited 3,000- and 4,000-fold higher 16S rRNA and nosZ clade I abundances, respectively, compared to upland soils. Cu addition significantly decreased 16S rRNA abundance, eliminated AOB amoA in upland soils, and slightly reduced the tested gene abundances in depression soils. …”
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18777
PDLB - Balance Sheet
Published 2024“…The combination of flat / decreasing costs and double-digit asset growth is very favorable for expense leverage.…”
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18778
Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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18779
Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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18780
Table 1_RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae.docx
Published 2024“…We confirmed that rfaH is required for the synthesis of capsule and lipopolysaccharide (LPS) by positively regulating the expression of CPS and LPS gene clusters. We found that the ΔrfaH mutant led to a significantly decreased mortality of K. pneumoniae in a mouse intraperitoneal infection model. …”