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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant genes » significant gender (Expand Search), significant benefits (Expand Search), significant changes (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
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2881
Oral L-Arginine Treatment Attenuates <i>Cryptococcus neoformans</i> Extrapulmonary Dissemination and Disease Progression
Published 2025“…Gene expression analysis showed distinct metabolic shifts, including upregulation of arginase-1 (Arg1) and proline metabolism genes, with concurrent suppression of nitric oxide synthase 2 (Nos2) in the brain during the late infection phase. …”
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2882
An improved <i>in vitro</i> 3T3-L1 adipocyte model of inflammation and insulin resistance
Published 2024“…In 72 h treated adipocytes, no significant differences were found in the viability, glucose uptake or insulin-sensitive and inflammatory gene expression. …”
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2883
Video 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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2884
Image 2_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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2885
Table 1_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.xls
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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2886
Data Sheet 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.docx
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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2887
Video 2_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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2888
Image 4_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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2889
Table 1_ROS-mediated membrane damage and antioxidant imbalance drive apple flesh browning during cold storage.docx
Published 2025“…Total antioxidant capacity decreased by ~25% in FB, accompanied by significant reductions in AsA and GSH and lower CAT/APX activities. …”
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2890
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
Published 2025“…Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …”
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2891
DataSheet1_Profiling of the serum MiRNAome in pediatric egyptian patients with wilms tumor.PDF
Published 2024“…In relation to WT clinicopathological features, decreased levels of hsa-miR-2355-3p showed a significant positive correlation with clinical stage (r = 0.6597, p = 0.0006) and WT metastasis (r = 0.439, p = 0.021). …”
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2892
The impact of nano-curcumin on cell viability and proliferation in breast cancer cells.
Published 2025“…(C, D) MTT assays were conducted on MCF7-S and MCF7-TR cells following nano-curcumin treatment. Cell viability significantly decreased at all tested time points. (E, F) mRNA Expression levels <i>PI3K</i>, <i>AKT1</i>, <i>mTOR</i>, <i>NF-KB</i>, <i>Cyclin D1</i>, <i>DILA1</i> and <i>PTEN</i> in breast cancer cells. …”
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2893
Table 1_Housed feeding improves rumen health by influencing the composition of the microbiota in Honghe cattle.docx
Published 2025“…For rumen microbiota, the HES group significantly decreased alpha diversity. The core rumen bacterial communities were Bacteroidata, Firmicutes and Proteobacteria. …”
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2894
Table 1_Emodin induced hepatic steatosis in BALb/c mice by modulating the gut microbiota composition and fatty acid metabolism.xlsx
Published 2024“…</p>Method and Results<p>Following an 8-week administration of emodin at doses of 25, 50, and 100 mg/kg/day,pathological analyses revealed that emodin significantly reduced the colon length, induced colonic crypt inflammation,diminished the colonic mucus layer,and decreased the fluorescence intensity of colonic tight junction proteins ZO-1 and Occludin. …”
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2895
Image 1_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif
Published 2025“…Here, we showed that the protein expression levels of FLI1 and AKT/p-AKT decreased with L1 treatment and that the RNA expressions of their downstream genes GATA1, TFRC, GYPA, CDKN1A and CDKN1B were also regulated by L1.…”
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2896
Image 2_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif
Published 2025“…Here, we showed that the protein expression levels of FLI1 and AKT/p-AKT decreased with L1 treatment and that the RNA expressions of their downstream genes GATA1, TFRC, GYPA, CDKN1A and CDKN1B were also regulated by L1.…”
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2897
Data Sheet 1_Distinct gut microbiota and metabolomic profiles in HBV-related liver cirrhosis: insights into disease progression.pdf
Published 2025“…Background<p>Hepatitis B virus (HBV)-related liver cirrhosis (HBV-LC) is a significant global health issue, affecting gut microbiota (GM) composition and metabolic processes. …”
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2898
Table 1_The impact of IL-17A inhibitors on scalp and gut microbiota in psoriasis.docx
Published 2025“…Regarding gut microbiota, significant differences in α-diversity richness were observed compared to healthy controls (P<0.05). …”
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2899
Image 2_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi...
Published 2025“…Cr(VI) stress significant increases in H<sub>2</sub>O<sub>2</sub> and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na<sup>+</sup>K<sup>+</sup>-ATPase, Ca<sup>2+</sup>-ATPase, and Mg<sup>2+</sup>-ATPase). …”
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2900
Image 3_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi...
Published 2025“…Cr(VI) stress significant increases in H<sub>2</sub>O<sub>2</sub> and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na<sup>+</sup>K<sup>+</sup>-ATPase, Ca<sup>2+</sup>-ATPase, and Mg<sup>2+</sup>-ATPase). …”