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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant genes » significant gender (Expand Search), significant benefits (Expand Search), significant changes (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
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3781
Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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3782
Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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3783
Table 1_RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae.docx
Published 2024“…We confirmed that rfaH is required for the synthesis of capsule and lipopolysaccharide (LPS) by positively regulating the expression of CPS and LPS gene clusters. We found that the ΔrfaH mutant led to a significantly decreased mortality of K. pneumoniae in a mouse intraperitoneal infection model. …”
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3784
Image 3_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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3785
Image 2_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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3786
MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway
Published 2024“…</p> <p>ATP binding cassette transporter 1 (ABCB1) had the highest mutation frequency and multiple mutation types in HNSCC, and the decreased ABCB1 was significantly related to better prognosis of HNSCC patients. …”
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3787
Image 1_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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3788
Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model
Published 2025“…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …”
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3789
Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx
Published 2025“…This study investigates the impacts of selenium (Se) and other heavy metals on soil microbial communities in selenium-rich mining areas using full-length 16S rRNA gene sequencing. Our results showed that Se and other heavy metal contamination significantly altered microbial community composition, favoring metal-tolerant phyla such as Proteobacteria, Actinobacteriota and Firmicutes, while reducing the abundance of sensitive groups like Acidobacteriota and Chloroflexi. …”
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3790
Data Sheet 1_Features and rhizosphere colonization strategies of Lactobacillus plantarum 0308 in soil-tomato systems.docx
Published 2025“…Further analyses revealed that LP0308 altered the rhizosphere soil microbial community, significantly increasing the abundance of Bacillus spp. while decreasing the potential pathogenic microorganisms, such as Ralstonia solanacearum and Fusarium oxysporum. …”
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3791
Table 2_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.docx
Published 2025“…This study investigates the impacts of selenium (Se) and other heavy metals on soil microbial communities in selenium-rich mining areas using full-length 16S rRNA gene sequencing. Our results showed that Se and other heavy metal contamination significantly altered microbial community composition, favoring metal-tolerant phyla such as Proteobacteria, Actinobacteriota and Firmicutes, while reducing the abundance of sensitive groups like Acidobacteriota and Chloroflexi. …”
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3792
Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes
Published 2024“…</p> <p>AST significantly enhanced SOD1 expression, reducing apoptosis and inflammation in damaged cells. …”
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3793
Disruption of <i>CmHmgr1</i> triggers apoptosis and causes defects in growth, conidiogenesis, and mycoparasitism of <i>Coniothyrium minitans</i>
Published 2025“…This mutant exhibited significantly reduced hyphal development, poor conidiation, and decreased sclerotial mycoparasitism. …”
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3794
Table 1_Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury.docx
Published 2025“…</p>Methods<p>Using transcriptome sequencing in a mouse model of IIRI, we identified potential biomarkers that were significantly upregulated in the IIRI group compared to the sham group. …”
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3795
Video 1_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.mp4
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”
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3796
Data Sheet 1_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.zip
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”
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3797
Table 3_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.xlsx
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”
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3798
Table 1_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.xlsx
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”
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3799
Table 2_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.xlsx
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”
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3800
Image 1_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.jpeg
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”