<i>PSAT1</i> gene as a biomarker for targeting triple negative breast cancer in presence of Rapamycin حسب Mehdi Roshanian Bakhsh (22469915)

"…The outcomes showed that the expression of the <i>decreased</i> gene by Rapamycin among other drugs increased in TNBC subtype compared to the other two subtypes including triple-positive and ER+/PR+. …"

Coherence of SCN metabolic pathways changes during development. حسب Martin Sládek (130663)

Fungal relative abundance links to FAV-eQTLs and variation in tissue-specific relative gene expression. حسب Emily P. Van Syoc (22169869)

"…<p><b>(A–F)</b> Individual genotypes for each FAV-eQTL associate with increased relative gene expression, decreased relative gene expression, or are heterozygous and possess one increased and decreased expression allele. …"

Trial design. حسب Llum Páez (22553360)

"…Vaccination against canine leishmaniasis intends to decrease the parasite burden and the risk of clinical disease. …"

Schedule of the trial. حسب Llum Páez (22553360)

"…Vaccination against canine leishmaniasis intends to decrease the parasite burden and the risk of clinical disease. …"

Clinical symptoms scoring system. حسب Llum Páez (22553360)

"…Vaccination against canine leishmaniasis intends to decrease the parasite burden and the risk of clinical disease. …"

Table 1_Expression and diagnostic values of ferroptosis-related genes in coronavirus-associated viral sepsis.xlsx حسب Yidan Zhang (130332)

"…Notably, PPI network analysis also identified IL1-β and HMOX1 as hub genes involved in ferroptosis. Finally, the results were verified in the validation set and clinical case samples, and the results showed that the expressions of IL1-β and HMOX1 in the coronavirus-associated viral sepsis group were decreased compared with the case control group and the healthy control group. …"

Image 1_Expression and diagnostic values of ferroptosis-related genes in coronavirus-associated viral sepsis.jpeg حسب Yidan Zhang (130332)

"…Notably, PPI network analysis also identified IL1-β and HMOX1 as hub genes involved in ferroptosis. Finally, the results were verified in the validation set and clinical case samples, and the results showed that the expressions of IL1-β and HMOX1 in the coronavirus-associated viral sepsis group were decreased compared with the case control group and the healthy control group. …"

Marketed vaccines against canine leishmaniasis. حسب Llum Páez (22553360)

"…Vaccination against canine leishmaniasis intends to decrease the parasite burden and the risk of clinical disease. …"

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx حسب Yu Zhou (89766)

"…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …"

Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx حسب Yu Zhou (89766)

"…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …"

Table 1_Pig-L mediates virulence, biofilm formation, and oxidative stress tolerance in Clostridioides difficile.docx حسب Yumei Cheng (12111117)

"…</p>Results<p>Deletion of the pig-L gene resulted in a significant reduction in C. difficile virulence, decreased biofilm formation, and increased susceptibility to oxidative stress. …"

Data Sheet 1_Enhancing AAV-microdystrophin gene therapy after repeat dosing by blocking phagocytosis.docx حسب Rita Spathis (187690)

"…</p>Results<p>Viral load was significantly increased by 77-fold in white blood cells after two rAAV9-microdystrophin doses compared to mice receiving a single dose. …"

Table 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.docx حسب Jing Lv (128179)

"…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"

Image 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.tif حسب Jing Lv (128179)

"…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"

IFN-responsive and anti-viral pathways are induced in γδ T cells post-HIV-1 acquisition. حسب Gina L. Griffith (20649097)

Data Sheet 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf حسب Maxim Sorokin (4379848)

"…However, tumor biosamples are usually formalin-fixed paraffin-embedded (FFPE) tissue blocks where RNA is heavily degraded, which in theory may result in decreased efficiency of fusion detection. Here, for the first time, we compared the efficacy of gene fusion detection by RNAseq for matched pairs of freshly frozen in RNA stabilizing solution (FF) and FFPE tumor tissue samples obtained from 29 human colorectal cancer patients. …"

Table 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.xlsx حسب Maxim Sorokin (4379848)

"…However, tumor biosamples are usually formalin-fixed paraffin-embedded (FFPE) tissue blocks where RNA is heavily degraded, which in theory may result in decreased efficiency of fusion detection. Here, for the first time, we compared the efficacy of gene fusion detection by RNAseq for matched pairs of freshly frozen in RNA stabilizing solution (FF) and FFPE tumor tissue samples obtained from 29 human colorectal cancer patients. …"

Table 2_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.xlsx حسب Maxim Sorokin (4379848)

"…However, tumor biosamples are usually formalin-fixed paraffin-embedded (FFPE) tissue blocks where RNA is heavily degraded, which in theory may result in decreased efficiency of fusion detection. Here, for the first time, we compared the efficacy of gene fusion detection by RNAseq for matched pairs of freshly frozen in RNA stabilizing solution (FF) and FFPE tumor tissue samples obtained from 29 human colorectal cancer patients. …"

Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf حسب Maxim Sorokin (4379848)

"…However, tumor biosamples are usually formalin-fixed paraffin-embedded (FFPE) tissue blocks where RNA is heavily degraded, which in theory may result in decreased efficiency of fusion detection. Here, for the first time, we compared the efficacy of gene fusion detection by RNAseq for matched pairs of freshly frozen in RNA stabilizing solution (FF) and FFPE tumor tissue samples obtained from 29 human colorectal cancer patients. …"