Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx حسب Carlos A. R. Sánchez (21288050)

"…Lipid metabolism was significantly altered in moderate-altitude athletes, including pathways such as linolenic and linoleic acid, sphingolipid, and arachidonic acid, as well as processes involving the transfer of acetyl groups into mitochondria and fatty acid biosynthesis. …"

Table 1_Study on the effect of different types of sugar on proliferation and inflammatory in goose fatty liver.docx حسب Shuang Yi (8698824)

"…Glucose combined with si-CPT1A treatment decreased CyclinD3 while increasing p21 expression. …"

Image 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif حسب M. Elakkya (21760439)

"…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …"

Image 2_Modulation of VR-HMD-induced cybersickness using cathodal transcranial direct current stimulation: a functional near-infrared spectroscopy study.jpeg حسب Seong Ho Yun (22686965)

"…Results showed that cathodal tDCS significantly reduced nausea-related cybersickness symptoms compared to sham stimulation (p < 0.05). fNIRS analysis revealed decreased oxyhemoglobin concentrations in the bilateral superior parietal lobule and angular gyrus following cathodal tDCS, indicating reduced cortical activity in these regions. …"

The structure of IRAU and Res2Net+ block [22]. حسب Yingying Liu (360782)

"…However, after removing the integrated residual attention unit and depth-wise separable convolution, the accuracy decreased by 1.91% and the latency increased by 117ms. …"

Table 1_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx حسب M. Elakkya (21760439)

"…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …"

Table 1_The impact of tumor burden score on prognosis in patients after radical resection of hepatocellular carcinoma: a single-center retrospective study.docx حسب Junzhang Huang (13237880)

"…</p>Conclusion<p>In patients undergoing radical resection for HCC, higher TBS was significantly related to shorter OS and RFS.</p>…"

DataSheet7_Refining dual RNA-seq mapping: sequential and combined approaches in host-parasitic plant dynamics.csv حسب Carmine Fruggiero (20143830)

"…The evolutionary distance between parasitic and host plants did not significantly impact the accuracy of read assignment to their respective genomes since enough polymorphisms were present to ensure reliable differentiation. …"

Does policy integration in renewable energy deployment enhance environmental sustainability in Africa? حسب Mary Donkor (20463828)

"…While renewable energy consumption decreases CO₂ emissions, it is associated with an increase in N₂O emissions. …"

Image 1_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.jpeg حسب M. Elakkya (21760439)

"…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …"

Data Sheet 9_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf حسب Didar Murad (12220805)

"…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …"

Image 12_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg حسب Chen Wang (88408)

"…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…"

Image 2_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif حسب Tengfei Tian (1793545)

"…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …"

Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx حسب Wenqiao Jia (12356306)

"…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca²⁺/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…"

Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx حسب Shenglan He (7641308)

"…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …"

Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf حسب Wei Gong (112494)

"…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …"

Image 1_Immunomodulatory effects of probiotic Lactobacillus brevis ZG2488 on SARS-CoV-2 vaccine responses in mice.tif حسب Mengshan Chen (14303892)

"…</p>Results<p>ZG2488 intervention significantly enhanced local mucosal humoral immunity in the respiratory tract (increased SARS-CoV-2-specific IgG in BALF) and systemic Th1 cellular immunity (increased IFN-γ secretion by splenocytes). …"

S1 File - حسب Shi-jie Wang (18569781)

"…The results showed that muscle TOR knockdown and endurance exercise significantly increased the climbing speed, climbing endurance, the expression of autophagy related gene 2(ATG2), silent information regulator 2(SIR2), and pparγ coactivator 1(PGC-1α) genes, and superoxide dismutases(SOD) activity, but it decreased the expression of the TOR gene and reactive oxygen species(ROS) level, and it protected the myofibrillar fibers and mitochondria of skeletal muscle in Drosophila on a high-salt diet. …"

Image 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... حسب Ting Yang (189879)

"…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …"

YOLOv8n structure diagram. حسب Yaojun Zhang (389482)

"…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…"