Showing 19,561 - 19,580 results of 21,342 for search '(( significant decrease decrease ) OR ( significant i decrease ))', query time: 0.51s Refine Results
  1. 19561

    Data Sheet 6_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

    Published 2025
    “…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
  2. 19562

    Image 8_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

    Published 2025
    “…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
  3. 19563

    Source data.zip by Xiaoyan Pan (21158717)

    Published 2025
    “…In vivo, melatonin significantly increased MT1R (melatonin receptor 1A) expression in BPA-treated mouse testicular cells and the content of catalase, superoxide dismutase 2, and glutathione, while decreasing the level of malondialdehyde. …”
  4. 19564

    Citation patterns of Cochrane Reviews and other systematic reviews: a bibliometric analysis by Louise Olsbro Rosengaard (20439098)

    Published 2025
    “…From 2008 and forward, the overall number of citations was similar between Cochrane Reviews and other systematic reviews (2018–2022: median difference <b>=</b> 5 [95% CI <b>=</b> 4.9–5.1] in favor of Cochrane Reviews; <i>p</i> = 0.83). …”
  5. 19565

    <b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b... by Weidong Qian (20813608)

    Published 2025
    “…The results demonstrated that IBC (4 μg/mL) significantly reduced the minimum inhibitory concentration (MIC) of AmB from 1 μg/mL to 0.25 μg/mL, indicating a fourfold increase in potency. …”
  6. 19566

    Table3_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx by Fen Hu (342627)

    Published 2024
    “…Further, MA was observed to induce prostate cancer cell autophagy by increasing the expression of p53, p-p53, ULK1, Beclin1, Atg7, and Atg5 and the ratio of LC3-II/I and concurrently decreasing the expression of ERK1/2 and mTOR. …”
  7. 19567

    Table2_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx by Fen Hu (342627)

    Published 2024
    “…Further, MA was observed to induce prostate cancer cell autophagy by increasing the expression of p53, p-p53, ULK1, Beclin1, Atg7, and Atg5 and the ratio of LC3-II/I and concurrently decreasing the expression of ERK1/2 and mTOR. …”
  8. 19568

    Percent of recording electrodes excited or inhibited by stimulation at different frequencies, amplitudes, and types of electrodes. by Uma R. Mohan (19950039)

    Published 2024
    “…<p>(<b>a</b>) Percent of recording electrodes showing significant high frequency activity increases and decreases for each stimulation frequency for depth and surface stimulation sites. …”
  9. 19569

    Table 2_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

    Published 2025
    “…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…”
  10. 19570

    Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx by Alexandra Prodea (22617710)

    Published 2025
    “…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …”
  11. 19571

    Table 3_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx by Zhuowen Hu (20431616)

    Published 2024
    “…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
  12. 19572

    Image 11_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

    Published 2024
    “…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
  13. 19573

    Image 12_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

    Published 2024
    “…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
  14. 19574

    Image 8_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png by Eyad Talal Attar (22124251)

    Published 2025
    “…</p>Result<p>Examination of eventrelated potentials (ERPs) demonstrated that P300 amplitude showed significant growth when responding to oddball stimuli, which indicates increased attention allocation (p < 0.05). …”
  15. 19575

    Table 9_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

    Published 2025
    “…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…”
  16. 19576

    Table 10_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

    Published 2025
    “…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…”
  17. 19577

    Image 10_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

    Published 2024
    “…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
  18. 19578

    Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

    Published 2025
    “…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”
  19. 19579

    Table 2_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx by Zhuowen Hu (20431616)

    Published 2025
    “…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
  20. 19580

    Image 8_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

    Published 2024
    “…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”