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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
i decrease » _ decrease (Expand Search), a decrease (Expand Search), _ decreased (Expand Search)
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6821
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6822
Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc...
Published 2025“…Pro-inflammatory cytokines IL-6, IL-1β, and TNF-α levels were significantly suppressed (<i>p</i> < 0.001). …”
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6823
Image 3_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Cochlear histology revealed reduced hair cell and spiral ganglion cell counts, as well as decreased Na<sup>+</sup>/K<sup>+</sup>-ATPase α1 expression and endocochlear potential. …”
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6824
Image 5_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Cochlear histology revealed reduced hair cell and spiral ganglion cell counts, as well as decreased Na<sup>+</sup>/K<sup>+</sup>-ATPase α1 expression and endocochlear potential. …”
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6825
Image 2_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Cochlear histology revealed reduced hair cell and spiral ganglion cell counts, as well as decreased Na<sup>+</sup>/K<sup>+</sup>-ATPase α1 expression and endocochlear potential. …”
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6826
Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Cochlear histology revealed reduced hair cell and spiral ganglion cell counts, as well as decreased Na<sup>+</sup>/K<sup>+</sup>-ATPase α1 expression and endocochlear potential. …”
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6827
<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b>
Published 2025“…After a median 8.7 months of follow-up, BMI (medianΔ -1.7; range -5.9 to 0.9 kg/m2; p=0.008), HbA1c (medianΔ -1.1%; range -6.3 to -0.1%; p<0.001), triglycerides [medianΔ -65 mg/dL (-0.73 mmol/L); range -3820 to 43 mg/dL (-43.2 to 0.49 mmol/L); p=0.003] and total daily insulin requirements (medianΔ -109; range -315 to 0 units/day; p=0.002) were significantly reduced. …”
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6828
Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx
Published 2025“…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…”
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6829
GluA1 promotes opioid use
Published 2025“…Pre-treatment with indomethacin, a non-opioid inhibitor of pain, before the pain induction blocked the decrease in morphine intake. In rats with steady MSA, the protein level of GluA1 subunits of glutamate AMPA receptors (AMPARs) was significantly increased, but that of GluA2 was decreased, resulting in an increased GluA1/GluA2 ratio in central nucleus of the amygdala (CeA). …”
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6830
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6831
Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif
Published 2024“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”
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6832
In Situ Transition of Amorphous Carbon to Graphite-like Structures Using MXene as a Template for Fast and Long-Lasting Macrosuperlubricity
Published 2024“…Friction tests indicate that, under high-stress conditions (∼1.5 GPa Hertz pressure), the coefficient of friction (CoF) of the composite films rapidly decreases to macroscopic superluberic regimes of ∼0.003, with a friction lifespan more than ten times that of the original H-DLC films. …”
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6833
In Situ Transition of Amorphous Carbon to Graphite-like Structures Using MXene as a Template for Fast and Long-Lasting Macrosuperlubricity
Published 2024“…Friction tests indicate that, under high-stress conditions (∼1.5 GPa Hertz pressure), the coefficient of friction (CoF) of the composite films rapidly decreases to macroscopic superluberic regimes of ∼0.003, with a friction lifespan more than ten times that of the original H-DLC films. …”
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6834
In Situ Transition of Amorphous Carbon to Graphite-like Structures Using MXene as a Template for Fast and Long-Lasting Macrosuperlubricity
Published 2024“…Friction tests indicate that, under high-stress conditions (∼1.5 GPa Hertz pressure), the coefficient of friction (CoF) of the composite films rapidly decreases to macroscopic superluberic regimes of ∼0.003, with a friction lifespan more than ten times that of the original H-DLC films. …”
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6835
In Situ Transition of Amorphous Carbon to Graphite-like Structures Using MXene as a Template for Fast and Long-Lasting Macrosuperlubricity
Published 2024“…Friction tests indicate that, under high-stress conditions (∼1.5 GPa Hertz pressure), the coefficient of friction (CoF) of the composite films rapidly decreases to macroscopic superluberic regimes of ∼0.003, with a friction lifespan more than ten times that of the original H-DLC films. …”
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6836
Image 2_PLK1 inhibition impairs erythroid differentiation.jpeg
Published 2024“…Although PLK1 inhibitors have emerged as promising therapeutic agents for cancer, their use has been linked to significant anemia in a subset of patients, yet the underlying mechanisms remain poorly understood. …”
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6837
Co–Fe–Mo Phosphides’ Triphasic Heterostructure Loaded on Nitrogen-Doped Carbon Nanofibers by Electrospinning as Efficient Bifunctional Electrocatalysts for Overall Water Splitting...
Published 2025“…The rational design of efficient and stable bifunctional electrocatalysts for the hydrogen evolution reactions (HER) and oxygen evolution reactions (OER) poses a significant challenge in realizing environmentally friendly hydrogen production through electrocatalytic water splitting. …”
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6838
Histogram of the extracted parameters.
Published 2025“…Logistic regression (n = 93) showed that a less steep contrast gradient (decreasing by 10 Hounsfield unit/%) was associated with a reduction in odds of the following short-term adverse outcomes: 48.1% for intensive care unit admission (odds ratio [OR] = 0.519, 95% confidence interval [CI]: 0.306–0.804), 29.3% for oxygen therapy >24 hours (OR = 0.707, 95% CI: 0.496–0.976), 60.6% for reperfusion therapy (OR = 0.394, 95% CI: 0.178–0.682), 57.5% for vasopressor therapy (OR = 0.425, 95% CI: 0.194–0.741), and 50.2% for PE-related death (OR = 0.498, 95% CI: 0.246–0.915). …”
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6839
6MWT results.
Published 2025“…Findings indicate that while adults with long COVID displayed normal pulmonary function at rest, including Forced Vital Capacity (FVC), Forced Expiratory Volume (FEV<sub>1</sub>), Total Lung Capacity (TLC), and resting Arterial oxygen saturation (SpO<sub>2</sub>)<sub>,</sub> significant impairments in exercise capacity were identified. …”
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6840
Flowchart of selected studies.
Published 2025“…Findings indicate that while adults with long COVID displayed normal pulmonary function at rest, including Forced Vital Capacity (FVC), Forced Expiratory Volume (FEV<sub>1</sub>), Total Lung Capacity (TLC), and resting Arterial oxygen saturation (SpO<sub>2</sub>)<sub>,</sub> significant impairments in exercise capacity were identified. …”