Effect of urea and K₂SO₄ on enzyme activity and biochemical changes of date fruit (<i>Phoenix dactilyfera</i> cv. ‘Zahedi’) during ripening by Narjes Fahadi Hoveyze (22376779)

“…<p>This study evaluated the effects of urea and potassium sulfate (K₂SO₄) at three concentrations (0, 0.5, and 1%) on the chemical and organoleptic properties of date fruit (<i>Phoenix dactylifera</i> L. cv. …”

Image 2_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). In contrast, most kinds of MGDGs, HexCers, Cers, PEs and FA (18:2) demonstrated a notable decrease in the hippocampus of AD group (p < 0.05, VIP > 1).…”

Table_1_RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance.DOCX by Jianmin Chen (330051)

“…RvE1 attenuated cardiac dysfunction in septic mice and increased cardiac phosphorylated Akt; decreased cardiac phosphorylated IκB kinase α/β, nuclear translocation of the NF-κB subunit p65, extracellular signal–regulated kinase 1/2, and c-Jun amino-terminal kinases 1/2. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…In this study, we present compound <b>19c</b>, which demonstrates promising efficacy both <i>in vitro</i> and <i>in vivo</i>. <b>19c</b> showed robust <i>in vitro</i> activity with an IC₅₀ value of 1.09 nM and limited blood–brain barrier penetration. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…In this study, we present compound <b>19c</b>, which demonstrates promising efficacy both <i>in vitro</i> and <i>in vivo</i>. <b>19c</b> showed robust <i>in vitro</i> activity with an IC₅₀ value of 1.09 nM and limited blood–brain barrier penetration. …”

Data Sheet 1_Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure.zip by Hui-Ying Liu (10193468)

“…</p>Results<p>Sepsis led to an increase in the expression of IL-6, TNF-α, and a decrease in the expression of occludin. After treatment with S. boulardii (CNCM I-745), the inflammatory damage with sepsis was reduced, and the expression level of occludin was significantly increased. …”

Table 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.xlsx by Xu-Zhe Yu (21509801)

“…Further, only HIF1A was upregulated in the advanced stage of PTC and significantly correlated with the dedifferentiation (all P < 0.05). …”

Image 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.tif by Xu-Zhe Yu (21509801)

“…Further, only HIF1A was upregulated in the advanced stage of PTC and significantly correlated with the dedifferentiation (all P < 0.05). …”

Image1_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…Overexpression of FGFR1 in BEAS-2B cells significantly enhanced cell proliferation and stimulated NF-ĸB transcriptional activity in HERK-293T cells. …”

Data Sheet 2_A high-calorie diet exacerbates lipopolysaccharide-induced pneumonia by promoting acetate-mediated macrophage polarization via the HDAC9/10–HIF-1α–glycolysis axis.pdf... by Qianqian Li (386223)

“…Taken together, we demonstrated that a high-calorie diet could cause acetate levels to decrease in mice with LPS-induced pneumonia. This decrease in acetate was associated with a diminished inhibitory effect on HDAC9/10, potentially contributing to upregulation of HIF-1α expression and increased glycolysis. …”

Data Sheet 1_A high-calorie diet exacerbates lipopolysaccharide-induced pneumonia by promoting acetate-mediated macrophage polarization via the HDAC9/10–HIF-1α–glycolysis axis.docx... by Qianqian Li (386223)

“…Taken together, we demonstrated that a high-calorie diet could cause acetate levels to decrease in mice with LPS-induced pneumonia. This decrease in acetate was associated with a diminished inhibitory effect on HDAC9/10, potentially contributing to upregulation of HIF-1α expression and increased glycolysis. …”

<b>L-Tryptophan as a Frontier in Diabetes Management: A Pilot Study</b> by dr.gayathri M rao (22045067)

“…A significant increase was seen in pancreatic GLP-1 levels in treatment group. …”

Rotarod performance. by Gerald Yu Liao (20490394)

“…</b> C57BL/6J mice at the same age groups also showed statistically significant age-related decrease in performance as seen in CB6F1J mice. …”

Table 1_Clinical performance of Hedia Diabetes Assistant bolus calculator for diabetes management: a real-world retrospective cohort study.docx by Kenney Fehrenkamp Pedersen (20944706)

“…After 12 weeks, LBGI significantly improved from 0.73 to 0.61 (17% decrease, P < 0.001) with no significant changes in HBGI, and eA1c. …”

Data Sheet 1_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.pdf by Zhang-Zhang Ji (21611168)

“…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…”

Table 1_Novel direct effect of CCR2 receptor on follicle activation process.docx by Yamila Gamaleri (21898103)

“…Moreover, there was a significant increase in the percentage of transitional follicles (and a decrease in primordial follicles), together with an increase in oocyte diameter compared with the control and the antagonist groups (p<0.05). …”

Image 1_Novel direct effect of CCR2 receptor on follicle activation process.pdf by Yamila Gamaleri (21898103)

“…Moreover, there was a significant increase in the percentage of transitional follicles (and a decrease in primordial follicles), together with an increase in oocyte diameter compared with the control and the antagonist groups (p<0.05). …”

Table 5_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.xlsx by Zhang-Zhang Ji (21611168)

“…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…”

Table 2_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.xlsx by Zhang-Zhang Ji (21611168)

“…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…”

Image 1_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.tif by Zhang-Zhang Ji (21611168)

“…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…”