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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
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7041
Image 1_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff
Published 2025“…Inhibition of ERK1/2 and JNK pathways decreased the secretion of cathepsin B after 48 h of IL-6/sIL-6R stimulation, and JNK inhibition reduced the secretion of cathepsin L under similar conditions.…”
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7042
Data Sheet 1_Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-anal...
Published 2025“…There was no statistically significant decrease in CD8<sup>+</sup> cells. For inflammation, lower-dose Tα1 could significantly reduce C-reactive protein (CRP) levels (mg/L) (MD=-30.12, 95%CI [-35.75, -24.49], P<0.00001), while higher-dose Tα1 showed no statistically significant difference (MD=-3.83, 95%CI [-12.14, 4.49], P=0.37). …”
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7043
Supplementary file 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.pdf
Published 2025“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”
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7044
Table 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx
Published 2025“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”
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7045
Table 2_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx
Published 2025“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”
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7046
Table 3_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.csv
Published 2025“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”
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7047
Table 4_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx
Published 2025“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”
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7048
Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip
Published 2025“…</p>Results<p>TBI significantly upregulated TREM-1 expression in microglia, peaking at 3 days post-injury (dpi). …”
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7049
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7050
<b>ART does not correct plasma virome and cytokine dysregulations induced by HIV-1</b>
Published 2024“…Notably, most cytokines dysregulated were not fully restored by ART, with abnormal levels of IL-10, GM-CSF, VEGF, and eotaxin, and a significantly increased level of plasma I-FABP. Anelloviruses showed significantly negative correlations with other commensal viruses except HPgV-1, but had positive corrections with several anti-inflammatory and Th1 cytokines.…”
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7051
Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
Published 2025“…Survival analysis was performed using the log-rank (Mantel–Cox) test (<b>D</b> and <b>E</b>) relative to sgCTRL (<b>D</b>) and to sgCTRL and sgKDM6A#1 (<b>E</b>). Error bars, SEM (<b>B</b> and <b>C</b>). *, <i>P</i> < 0.05; **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001; ****, <i>P</i> < 0.0001; ns, not significant. …”
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7052
Image 4_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7053
Image 6_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7054
Image 8_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7055
Image 3_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7056
Image 7_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7057
Image 2_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7058
Image 5_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7059
Image 1_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif
Published 2025“…Sputum protein levels did not correlate with bacterial burden and did not consistently decrease following one month of drug therapy. Only PDL-1 was detectable in mouth swab samples. …”
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7060
Evaluation results of eye detection approaches.
Published 2024“…Within each region, keys are highlighted one by one for selection. An experiment compared the multi-stage approach to single-step techniques, having participants copy text using eye gaze alone under both conditions. …”