<b>Mass, Residency Duration, and Previous Experience Shape Post-Escalation but Not Pre-Escalation Outcomes in Experimental Territorial Contests of Atlantic Mudskippers (</b><b><i>P... by Michael Smith (21714377)

“…A binomial generalized linear model with logit link estimated the probability of resident escalation as a time-dependent, predictor-driven decision process, while generalized linear models examined how predictors influenced the resident’s total assessment duration in escalated contests and the post-escalation contest duration. We hypothesized that (1) heavier residents with longer residency durations would be more likely to escalate and win, (2) prior outcomes would influence subsequent contests, and (3) total assessment and post-escalation contest durations would increase as asymmetries in mass and residency duration decreased. …”

Data Sheet 1_Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation.zip by Raheem F. H. Al Aameri (14951800)

“…<p>Cisplatin is a chemotherapy drug used to treat different solid tumors, including ovarian, bladder, lung, and head and neck cancers. One of its significant side effects is ototoxicity, especially when high doses are required. …”

Localization and expression of cell-to-cell connection proteins in bma-miRNA transfected and NC hLECs. by Hailey Johnson (18217167)

“…(<b>I</b><b>–</b><b>K)</b> ITGB1 (red) expression appears similar across treatment groups (I – NC, J – bma-miR-5864, and K – bma-mir-86), with mildly decreased expression observed in parasite miRNA-treated cells (J, K). …”

Data Sheet 1_Efficacy and safety of anlotinib combined with 125I seed implantation for iodine-refractory thyroid cancer.docx by Zhijun Chen (254277)

“…Serum Tg levels declined significantly from baseline in all groups. No major procedural complications occurred, and treatment-related adverse reactions were mostly mild (Grade 1–2) and comparable among groups.…”

Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf by Man Zhao (314232)

“…Treatment with MitoTEMPO after BNIP3 silencing further decreases the expression of NLRP1, while overexpression of NLRP1 nullifies the impact of BNIP3 knockdown. …”

Data Sheet 1_Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.docx by Rui Sun (177521)

“…Tcirg1 deficiency in knockout mice delayed OA progression, as evidenced by reduced cartilage damage, improved subchondral bone mass, and decreased osteoclast activity. …”

The Type I JAKinib, ruxolitinib, promotes pJAK1 and pJAK2 phosphorylation in MSCs from salivary glands. by Ilya Gurevic (1326786)

“…Error bars represent standard deviation; *p = 0.05; p = **** < 0.0001 represent the ANOVA-derived significance for the difference between all values. I = IFN.…”

Image 1_Unveiling the intricacies: small interfering RNA targeting Snail-1 unravels dynamics in endometrial carcinoma cell behavior.jpeg by Feng Li (30515)

“…Moreover, transfection correlated with increased apoptosis and decreased migration of treated HEC-1A cells.</p>Conclusion<p>The study emphasizes the significant influence of Snail-1 on EMT in EC cells, thereby impacting apoptosis and metastasis. …”

Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip by Alessia Cavallo (13036581)

“…The lipid composition was investigated by GCMS and LCMS.</p>Results<p>Both Th1/Th17 and Th2 cytokine mixtures changed the expression of genes involved in the metabolism of fatty acids (FAs), i.e., FAS, FADS2, SCD1, and ALOX12B. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Table 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

“…</p>Methods<p>Firstly, the expression of LAMP1 in ccRCC and its clinical significance were analyzed using various databases. …”

Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

“…</p>Methods<p>Firstly, the expression of LAMP1 in ccRCC and its clinical significance were analyzed using various databases. …”

Table 1_Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study.docx by Ali M. Alaseem (21709589)

“…In summary, our study highlights GLO-1 as a significant biomarker across multiple cancers that plays a key role in cancer progression, immune modulation, and therapeutic response.…”

Data Sheet 1_Serum VEGF and ANGPT1 as angiogenesis markers may predict the outcomes of older adults with hip fractures.xlsx by Yuan Yao (31223)

“…Multivariate Cox regression models indicated that low VEGF and ANGPT1 were independent risk factors for one-year mortality, while ANGPT2 did not show significant prognostic value.…”

Table 1_Assessing and projecting the global impacts of Alzheimer’s disease.docx by Nanlong Zhang (20563511)

“…</p>Results<p>The projected global burden of Alzheimer’s disease from 2022 to 2030 indicates a decrease in DALYs, with an Estimated Annual Percentage Change (EAPC) of −1.44 (95% CI: −1.45, −1.42). …”

Image1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Table1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.docx by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Data Sheet 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf by Linjie Peng (12553717)

“…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …”

Supplementary file 1_EEG activity over ipsilateral and contralateral M1 during simple and complex hand tasks: variations with motor learning.docx by Jun Zhao (59250)

“…However, after 10 training sessions, the electrodes over iM1 activation increased during complex tasks but decreased during simple task for both hands, eliminating significant differences in activation levels between simple and complex tasks. …”

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

“…Further mechanistic investigations reveal that the Omicron subvariant is ineffective in using TMPRSS2 compared with ancestral SARS-CoV-2 (HKU-001a) and previous variants, which may contribute to its decreased replication in Calu3 and Caco2 cells. In K18-hACE2 transgenic mice, the replication capacity of the Omicron subvariant is significantly attenuated in both the upper and lower respiratory tracts of virus-infected animals when compared to that of the ancestral strain and Delta (B.1.617.2) variant, correlating with substantially ameliorated lung pathology. …”