Table 2_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx by Linjie Peng (12553717)

“…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …”

Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls by Linjie Peng (12553717)

“…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …”

<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... by Silvia Torchio (611349)

“…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. …”

The MIC values of DDAB for the different strains. by Yuqi Tian (6733070)

“…Moreover, DDAB inhibited the expression of <i>Salmonella</i> pathogenicity island 1 (SPI-1) to decrease the adhesion and invasion ability of <i>S</i>. 4,[5],12:i:- in IPEC-J2 cells, whereas the deletion of <i>sugE2</i> increased the adhesion and invasion ability. …”

Efficacy and Safety of Topical Loteprednol Etaponate 0.5% and Topical Dexamethasone 0.1% in Post Cataract Surgery in Iraqi Patients. .csv by Leqaa Taha (20141172)

“…</p><p dir="ltr"><b>Results:</b> Sixty-six eyes of 66 patients were enrolled (33 patients in group A and 33 in group B) with no clinically significant differences related to age or gender between the two groups, the intraocular pressure was 16.45 ± 3.00, and 16.42± 2.76 mmHg in group A and B respectively preoperatively which was clinically insignificant with p-value 0.522 and decreased slightly after the surgery 15.82± 3.005 and 15.61± 2.817mmHg in group A and B respectively after one week postoperatively but also clinically insignificant and was 15.58± 2.211 and 16.55± 4.452 mmHg in group A and B after four weeks postoperatively and all these changes in IOP was clinically insignificant.…”

Table 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 4_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

(A-H). Case 1: primary subcutaneous facial alveolar echinococcosis. by Louis Bohard (22250661)

“…Histopathology of the frontal lesion. <b>(E)</b>. <i><i>Echinococcus (E) multilocularis</i></i> microcyst (*) delineated by the laminated layer (1), surrounded by an intense granulomatous reaction (2) and the invaded striated muscle (3). …”

Data Sheet 1_Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancer.docx by Bridget E. Crossman (18230326)

“…</p>Results<p>Overexpression of MerTK in TNBC syngeneic mouse models leads to a marked delay in tumor growth, coupled with significant increases in anti-tumor M1 macrophage, CD4+ T cell, active CD8+ T cell, active NK cell, and NKT cell populations. …”

Data Sheet 2_Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization.docx by Yunbo Wu (9127390)

“…</p>Results<p>Participants were grouped by gastric mucosal pathology: normal (NOR), gastric inflammation (GI), gastric atrophy (GA), gastric premalignant lesion (GPL), severe dysplasia (GSD), and gastric cancer (GC). No significant differences were found in CDH1 rs16260 genotypes. …”

Table 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf by Usman Sunusi (22274329)

“…Background<p>Cardiac complications in patients with hypereosinophilia cause significant morbidity and mortality. However, mechanisms of how eosinophilic inflammation causes heart damage are poorly understood.…”

Presentation 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf by Usman Sunusi (22274329)

“…Background<p>Cardiac complications in patients with hypereosinophilia cause significant morbidity and mortality. However, mechanisms of how eosinophilic inflammation causes heart damage are poorly understood.…”

Table 2_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.xlsx by Usman Sunusi (22274329)

“…Background<p>Cardiac complications in patients with hypereosinophilia cause significant morbidity and mortality. However, mechanisms of how eosinophilic inflammation causes heart damage are poorly understood.…”

Data Sheet 1_Functional characterization of cutinase genes NsCut1-NsCut4 in Neostagonosporella sichuanensis and their effects on fishscale bamboo.pdf by Mengyao Lu (11447488)

“…Gene knockout experiments were performed to construct deletion strains ΔNsCut and corresponding complemented strains ΔNsCut+. Notably, ΔNsCut1 and ΔNsCut3 resulted in reduced pigmentation, decreased spore production, and increased sensitivity to NaCl, H₂O₂, and Congo red, along with reduced pathogenicity—indicating that these genes play key roles in metabolic and reproductive processes, oxidative stress responses, and the maintenance of cell wall integrity. …”

Data Sheet 1_Shenmai Injection enhances short-term outcomes in ischemic stroke patients after thrombolysis via AMPKα1.docx by Jing Wu (54032)

“…Mechanistic studies revealed that these protective effects were partially mediated through the AMPKα1.</p>Conclusion<p>SMI significantly improves short-term outcomes in IS patients treated with rt-PA thrombolysis. …”

List of DEGs from neuronal cell analysis. by Sara Cuvertino (18892069)

“…In KS1 iPSCs we detected significantly lower levels of functional <i>KMT2D</i> transcript and KMT2D protein, and lower global H3K4me1, H3K4me2 levels and modest reduction in H3K4me3. …”

List of HipSci cell lines used in the study. by Sara Cuvertino (18892069)

“…In KS1 iPSCs we detected significantly lower levels of functional <i>KMT2D</i> transcript and KMT2D protein, and lower global H3K4me1, H3K4me2 levels and modest reduction in H3K4me3. …”

Table 1_Techno-economic analysis of ocean iron fertilization.docx by C. Ward (7771667)

Data Sheet 1_Efficacy of hemoadsorption in the severe course of COVID-19.docx by Aleksei Yurievitch Yakovlev (20837198)