Data Sheet 1_The effect of mepolizumab dosage form on treatment outcomes in severe asthma.pdf by Martina Vetchá (21143222)

Table 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.docx by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Image 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.tif by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Image 2_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.jpeg by Zebanuer Yuemaierjiang (22702064)

“…Treatment with β-PGG impeded the G0/G1 or S phase to G2/M phase. Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”

Supplementary file 1_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.docx by Zebanuer Yuemaierjiang (22702064)

“…Treatment with β-PGG impeded the G0/G1 or S phase to G2/M phase. Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”

Image 1_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.png by Zebanuer Yuemaierjiang (22702064)

“…Treatment with β-PGG impeded the G0/G1 or S phase to G2/M phase. Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”

Table1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.pdf by Wenchao Tang (14710556)

“…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …”

Image1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.png by Wenchao Tang (14710556)

“…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …”

Image 1_Pharmacokinetic effect of disease severity and use of extracorporeal membrane oxygenation in critically ill Asian patients receiving vancomycin.jpg by Charul Avachat (20787341)

“…</p>Conclusion<p>The study demonstrates that ECMO and infection severity are major factors influencing vancomycin clearance in critically unwell pediatric patients. The significant decrease in clearance linked to ECMO and reduced infection severity underscores the necessity for meticulous therapeutic drug monitoring and tailored dosing strategies to enhance vancomycin treatment in this at-risk population. …”

Supplementary file 1_Antibiotic pretreatment inhibits white band disease infection by suppressing the bacterial pathobiome.docx by Jason D. Selwyn (2633932)

Data Sheet 1_Examining immersive audio’s role in flow and gaze behavior in pseudo-VR environments.docx by Quncan Huang (22617845)

Image 1_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…</p>Results<p>Compared with tumor nests in non-STAS patients, HLA-DRB5 and RASGRF1 were significantly less expressed in compartments of STAS, suggesting their inhibitory roles in the occurrence of STAS. …”

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

Table 1_Safety and efficacy of canine recombinant IL-15 in mammary gland tumors.docx by Min-Hee Kang (811734)

“…Dogs in the rcIL-15 group showed significantly improved QoL, particularly in pain, appetite, and activity. …”

Table 1_Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission.xlsx by Michele Francesco Di Tolla (12503167)

“…For instance, Leptin and Insulin levels decreased, particularly in Breast cancer patients, whereas Colorectal cancer patients exhibited a reduction in pro-inflammatory cytokines such as IL-1β, IL-6, IL-8, and TNF-α, even in the absence of weight loss and bioimpedential feature changes. …”

Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx by Thibaud Dauphin (21196820)

Supplementary file 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

“…Moreover, the transcription actor CARHSP1 exhibited apositive correlation with the proportion of HLA_DR⁺ Tregs. …”

Table 1_Biliary microbiota in disease-free, obstructive and post-drainage biliary tracts.docx by Guiyuan Zhang (13994877)

“…</p>Methods<p>A metagenomic sequence analysis of bile samples from patients with MBO who underwent percutaneous biliary drainage (PTBD) at our center from 1st May 2021 to 1st March 2022, which were divided into 2 groups, as the MBO group (n = 29) and BD group (n = 27). …”

Data Sheet 1_High humidity environment increases FBG by impairing the intestinal barrier.zip by Yao Wang (102387)

Table 1_The mechanism of Guanxin Qiwei dropping pills target Dubosiella to improve atherosclerosis.docx by Yuanhong Liao (359147)

“…Additionally, GXQW reduced total cholesterol (TC) and triglyceride (TG) levels, decreased the concentrations of inflammatory cytokines interleukin-6 (IL-6) and interleukin-1beta (IL-1β), suppressed malondialdehyde (MDA) activity, and elevated superoxide dismutase (SOD) levels. …”