Investigating the Impact of Base Pair Mismatches on Cas13d Cleavage Efficiency Using Molecular Dynamics Simulations by Ye Liu (296340)

“…However, the presence of mismatches significantly undermines the cleavage efficiency of Cas13d to target RNA. …”

Figure 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal by Ángel Fernández-Sanromán (20814476)

“…<b>E,</b> Schematic representation of a linear regression framework to identify correlates of within-patient expression changes in each of 14,120 genes, including <i>cis</i> effects of increased/decreased gene dosage and variation in purity. …”

JAK/STAT signaling promotes high global translation rates in CySCs. by Ruoxu Wang (9312306)

“…(<b>I</b>) Quan<i>t</i>ification of OPP incorporation in 1st row cyst cells (CySCs) normalized to levels in the hub. …”

Data Sheet 1_Meiotic chiasmata variations in the H genome among Triticeae species of varying ploidy.docx by Ying Yang (24175)

“…The number of chiasmata in the H genome decreased from 21.32 in H. bogdanii to 19.00 in E. sibiricus and 14.67 in H. brevisubulatum per genome during diakinesis, with a further significant reduction observed at metaphase I. …”

Table 1_Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study.docx by Xinyi Song (2207233)

“…</p>Results<p>In the 3-month analysis of 1411 patients, the cooling group showed significantly lower odds of achieving PASI 75 (adjusted OR 0.70, 95% CI 0.61–0.80, P <.001), PASI 90 (adjusted OR 0.68, 95% CI 0.59–0.79, P <.001), PGA 0/1 (adjusted OR 0.65, 95% CI 0.57–0.75, P <.001), and DLQI MID (adjusted OR 0.86, 95% CI 0.75–0.99, P = .032) compared to the warming group. …”

Image 1_Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study.tif by Xinyi Song (2207233)

“…</p>Results<p>In the 3-month analysis of 1411 patients, the cooling group showed significantly lower odds of achieving PASI 75 (adjusted OR 0.70, 95% CI 0.61–0.80, P <.001), PASI 90 (adjusted OR 0.68, 95% CI 0.59–0.79, P <.001), PGA 0/1 (adjusted OR 0.65, 95% CI 0.57–0.75, P <.001), and DLQI MID (adjusted OR 0.86, 95% CI 0.75–0.99, P = .032) compared to the warming group. …”

The impact of nano-curcumin on cell viability and proliferation in breast cancer cells. by Taraneh Givi (22793530)

“…(C, D) MTT assays were conducted on MCF7-S and MCF7-TR cells following nano-curcumin treatment. Cell viability significantly decreased at all tested time points. (E, F) mRNA Expression levels <i>PI3K</i>, <i>AKT1</i>, <i>mTOR</i>, <i>NF-KB</i>, <i>Cyclin D1</i>, <i>DILA1</i> and <i>PTEN</i> in breast cancer cells. …”

Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis by Shivam Kumar Pandey (22295532)

“…Exposure to LPS and FeSO₄ increased the DMT1, Bax, caspase-3, and alpha-synuclein, and decreased the GPX4, FTH1, SLC7A11, Nrf2, Keap1, HO-1, PARK7, Bcl-2, NeuN, and TH levels, resulting in cell ferroptosis, apoptosis, and dopaminergic cell death. …”

Data Sheet 1_Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept.docx by Ting Wang (16292)

“…Patients with 2 alleles of SE had higher levels of anti-CCP (p=0.02) and IgM RF (p=0.04) compared to patients with 0 or 1 allele. Further, IgM RF and CXCL13 levels decreased only in responders (p=0.02 and 0.004 respectively, at week 24), while anti-CCP levels did not decrease significantly in either responders or nonresponders.…”

Table 1_Efficacy of Yang Yin Sheng Xue formula against canine lymphoma chemotherapy-induced myelosuppression.docx by Wanbing Pan (22035863)

“…In the clinical phase, a decrease in complete blood count (CBC) indicators was observed after the eighth chemotherapy cycle in multicentric lymphoma canines, significantly delaying the onset of chemotherapy-induced reductions (p < 0.05) compared to the Control Group (third chemotherapy cycle).…”

Image 1_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. …”

Supplementary file 1_Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study.docx by Ji-Xin Tian (21710993)

“…</p>Results<p>In Chinese MDS patients, the average C₀ and C₆ of VEN were 1990.60 ± 1,591.12 ng/mL and 2,966.66 ± 1,406.96 ng/mL, respectively, with large interindividual variability. …”

Table 1_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.docx by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. …”

Data Sheet 1_Impact of primary production and net ecosystem metabolism on carbon and nutrient cycling at the land-sea interface.docx by Louise C. V. Rewrie (21016172)

“…A significant finding is that a seasonal decrease in dissolved inorganic carbon of 125 – 160 µmol kg^-1 from May to September, and in total alkalinity of 116 – 128 µmol kg^-1 from December to August, was likely driven by the concurrent and significant seasonal uptake of inorganic carbon by primary producers in the upper estuary and upstream regions. …”

Data Sheet 1_Feasibility of trancutaneous auricular vagus nerve stimulation in Black and Hispanic/Latino people with peripheral neuropathy.pdf by Marlon L. Wong (20573531)

“…Tingling sensation and pain decreased by median values of 2.0 and 1.5, respectively. …”

Data Sheet 1_Single-cell and transcriptomic analyses reveal the role of PCDH17 in the non-inflammatory tumor microenvironment of pancreatic cancer.zip by Yong Sun (406434)

Effects of nano-curcumin on cell migration. by Taraneh Givi (22793530)

“…Statistical analysis was conducted using a student t-test or one-way ANOVA and means ± SEM were displayed. ns = not significant, *<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001, ****<i>p</i> < 0.0001.…”

Table 1_Influence of intraoperative electromyographic changes and surgical extent on post-thyroidectomy esophageal motility: a prospective cohort study.docx by Mehmet Gunay (14384565)

Table1_Investigation of the effects of Periplaneta americana (L.) extract on ischemic stroke based on combined multi-omics of gut microbiota.XLSX by Xin Yang (104842)

Data Sheet 1_Differential effects of physical activity on behavioral and prefrontal responses during repetitive inhibitory control in older adults.docx by Jae-Hoon Lee (334543)

“…The PA group showed a significant decrease in reaction time across repetitions (p < 0.001), whereas no such change was observed in the PI group. …”