Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Data Sheet 1_Consistent microbial responses during the aerobic thaw of Alaskan permafrost soils.docx حسب Joy M. O’Brien (18927811)

Table 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.xlsx حسب Yi Kang (387134)

"…</p>Result<p>MR analysis indicated that glucosamine was associated with increased cognitive performance (p = 8.46E-04), FIS (p = 7.50E-04), ALM (p = 6.45E-08), WBFM (p = 1.97E-03), usual walking pace (p = 2.55E-07), and moderate to vigorous physical activity levels (p = 3.29E-03), but associated with decreased FA risk (p = 3.77E-05) and DNA methylation GrimAge acceleration (p = 0.001). …"

Table 1_Strawberry-herb intercropping: a 2-year study toward sustainable intensification and diversification.docx حسب Sebastian Soppelsa (5776868)

"…Our results showed significant year-to-year variation. Although strawberry plants intercropped with herbs in 2021 achieved a fruit production that was not significantly different from that of pure stand (on average 150 g plant⁻¹), the intercropping systems outperformed monocropping as revealed by indices such as land equivalent ratio (LER) and income equivalent ratio (IER) both greater than one. …"

Supplementary file 1_Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation.docx حسب Joël Illi (21449474)

Table 1_Association between body composition in early pregnancy and the risk of gestational diabetes mellitus.docx حسب Yan Li (23143)

"…</p>Results<p>Compared with the bottom tertile, the top tertile levels of PBF and FM were significantly associated with an increased risk of GDM, with adjusted odds ratios (ORs) and corresponding 95% confidence intervals (95% CI) of 1.77 (1.13, 2.77) and 1.99 (1.23, 3.20), respectively. …"

Data Sheet 1_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip حسب Fengli Ye (22123540)

"…PPI network analysis highlighted IL1B, IL6, and CCL2 as central nodes. Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. …"

Table 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.xlsx حسب Yan Li (23143)

Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

"…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Data Sheet 1_Perceptions and needs of patients, caregivers and health professionals regarding an oncology community center: a qualitative study.pdf حسب Inbal Mitnik (21611342)

Table 1_The impact of high-standard farmland construction policy on disaster vulnerability of food production systems: evidence from China.xlsx حسب Zeng Wei (12013901)

Data Sheet 1_Characterization of the Vibrio anguillarum VaRyhB regulon and role in pathogenesis.docx حسب Yingjie Li (2106778)

"…</p>Results<p>The small RNA called VaRyhB identified in V. anguillarum strain 775 is significantly longer than that in Escherichia coli. Transcriptomic analysis revealed that VaRyhB is critical for iron homeostasis under limited iron conditions, and deletion of VaRyhB resulted in lower expression levels of certain genes for siderophore biosynthesis and transport, thereby leading to impaired growth, reduced siderophore production, and decreased pathogenesis. …"

Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx حسب Jingjing Chen (293564)

"…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…"

Table_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.docx حسب György Szklenarik (20296893)

"…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"

Supplementary file 1_Quantitative microbial taxonomy across particle size, depth, and oxygen concentration.zip حسب Paulina Huanca-Valenzuela (21414911)

"…</p>Methods<p>In this study, we quantified microbial diversity using a fractionation method that separated particles into seven fine scale fractions (0.2–1.2, 1.2–5, 5–20, 20–53, 53–180,180–500, >500 μm), and included a spike-in standard for sequencing the 16S rRNA gene. …"

Data Sheet 1_Improving tea quality and fruit yield through intercropping with climbing plants.pdf حسب Qing Liao (1466149)

"…All intercropping treatments significantly increased tea leaf chlorophyll a, b, and total chlorophyll content compared with monoculture (CK), with maxima in PE-H (1.188, 0.447, and 1.635 mg/g) and SG-H (1.166, 0.425, and 1.591 mg/g), respectively. …"

DataSheet1_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.docx حسب Weina Xu (558990)

"…PTPRD-AS1 knockdown decreased the proliferation, cloning, and migration of CAOV3 cells.…"

Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization حسب Yu-Xuan Yao (21338594)

"…Two-stage network MR analyses were conducted to assess the mediation effect of inflammatory proteins on the relationships between GLP1R agonists and kidney diseases.</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …"

Data Sheet 1_Intratumoral microbiota composition in women’s cancers: a systematic review and meta-analysis.docx حسب Qin Wen (3505655)

"…In comparisons between tumor and benign tissues, the Chao1 index was decreased (SMD = -0.64, 95% CI: [-1.20, -0.08], I² = 0%), while the Simpson index was increased (SMD = 0.36, 95% CI: [0.01, 0.71], I² = 0%) in patients with ovarian cancer. …"

Stress responses to different light colours. حسب Solène Guenat (12187937)