Table 1_Propolis supplementation on inflammatory and oxidative stress biomarkers in adults: a systematic review and meta-analysis of randomized controlled trials.docx by Hossein Bahari (16704768)

“…This meta-analysis revealed that propolis consumption led to a significant decrease in C-reactive protein (CRP) (WMD: –1.23; 95%CI: –1.76, –0.69; p < 0.001), Interleukin-6 (IL-6) (WMD: –1.52; 95%CI: –2.10, –0.93; p < 0.001), Tumor necrosis factor-α (WMD: –1.15; 95%CI: –1.75, –0.55; p < 0.001), and Monocyte chemoattractant protein-1 (MCP-1) (WMD: –35.33; 95%CI: –50.28, –20.37; p < 0.001), and a significant increase in total antioxidant capacity (TAC) (WMD: 0.32; 95%CI: 0.12, 0.51; p = 0.001), Glutathione (GSH) (WMD: 4.71; 95%CI: 3.17, 6.25; p < 0.001), and Glutathione peroxidase (GPx) (WMD: 44.75; 95%CI: 5.10, 84.40; p = 0.02). …”

DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx by Yuhan Zhang (2792089)

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx by Xuan Zhao (356028)

“…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …”

Table 1_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.xls by Dang Li (16400478)

“…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …”

Table 1_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

Image 1_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg by Dang Li (16400478)

“…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …”

Table 1_Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis.docx by Yichuan Xv (18702754)

“…Acupuncture also reduced gastric tube indwelling time [MD = −2.36, 95% CI (−3.14, −1.59), p < 0.001], decreased gastric juice drainage [MD = −166.88, 95% CI (−176.57, −156.18), p < 0.001], and improved serum motilin levels [MD = 41.65, 95% CI (30.14, 53.15), p < 0.001]. …”

Table 1_Weight loss increases circadian gene expression and emotional well-being in individuals with obesity.docx by Carmen Grau-del Valle (22686341)

“…Several circadian genes were upregulated, including CLOCK, ARNTL, CRY1, DBP, and NR1D1; with associations found between CLOCK and lower state anxiety at baseline, and between CRY2 and higher self-esteem and lower depression at baseline (p < 0.05).…”

Table 1_Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of OATF against kidney stones.xlsx by Sisi Dai (7837886)

Supplementary file 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

“…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…”

Data Sheet 1_Distribution of different plant life forms on tropical islands: patterns and underlying mechanisms.docx by Chengfeng Yang (3333489)

“…Introduction<p>Island biogeography theory posits that both island area and isolation significantly influence species distribution patterns and community structure. …”

Table 1_Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health.xls by Yinchun Lv (18181816)

“…Background<p>Growing evidence suggests that chronic inflammation, resulting from intricate immune system interactions, significantly contributes to the onset of psychiatric disorders. …”

Table 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx by Peijin Li (220400)

“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf by Alex Ramos (16267028)

“…</p>Results<p>VWF, VCAM-1, and ROS expression was significantly higher in cells exposed to PE sera vs. control (12.3 ± 8.1, 3.6 ± 2.3, and 1.8 ± 0.2, respectively, p < 0.05), though significantly lower in cells exposed to depleted PE (dPE) sera (6.1 ± 2.7, 0.7 ± 0.6, and 1.2 ± 0.1, respectively, vs. control, p < 0.05). …”

Table 1_Multicenter epidemiology of Stenotrophomonas maltophilia bloodstream infections in Indian ICUs: building digital surveillance network.pdf by Parul Singh (191877)

“…Central line-associated BSIs (CLABSIs) predominated (64.9%), though their proportion decreased over time, with non-CLABSIs rising from 7.4% (2017–18) to 42.1% (2023–24). …”

Table 1_Circulating microRNA signatures as potential biomarkers differentiating diabetic, prediabetic, and healthy individuals.docx by Hanifa J. Abu-Toamih Atamni (22555724)

“…Correlation analyses highlighted miRNAs associated with glucose/HbA1c, alongside relationships among vitamin D status, glycemia, and platelet function.…”

Table 1_Disc degeneration influences the strain magnitude and stress distribution within the adjacent trabecular bone.docx by Kay A. Raftery (17080234)

“…Introduction<p>Up to one in five will suffer from osteoporotic vertebral fracture within their lifetime. …”

Data Sheet 1_Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.pdf by Lucie Pejšková (20467025)

Supplementary file 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.docx by Yan Li (23143)