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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
i decrease » _ decrease (Expand Search), a decrease (Expand Search), _ decreased (Expand Search)
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14181
DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip
Published 2024“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. …”
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14182
Raw data for main and supplemental figures
Published 2025“…We found that deletion of <i>proQ</i> significantly enhanced cell adherence ability of EHEC and led to upregulation of the locus of enterocyte effacement (LEE) pathogenicity island. …”
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14183
Supplementary file 3_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co...
Published 2025“…</p>Material and methods<p>Two hundred nursery pigs were assigned to one of five dietary treatments: (1) CON: a basal corn-soybean meal diet, (2) A: basal diet with 0.05% probiotics, (3) B: basal diet with 0.1% synbiotics containing one strain, (4) C: basal diet with 0.1% synbiotics containing two strains, and (5) D: basal diet with 0.1% enzyme cocktail.…”
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14184
Supplementary file 2_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co...
Published 2025“…</p>Material and methods<p>Two hundred nursery pigs were assigned to one of five dietary treatments: (1) CON: a basal corn-soybean meal diet, (2) A: basal diet with 0.05% probiotics, (3) B: basal diet with 0.1% synbiotics containing one strain, (4) C: basal diet with 0.1% synbiotics containing two strains, and (5) D: basal diet with 0.1% enzyme cocktail.…”
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14185
Supplementary Material for: The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis.
Published 2025“…PON1 levels showed no significant difference (effect size = -3.56, 95% CI [-8.63 to 1.51], p = 0.051). …”
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14186
PDLB - Balance Sheet
Published 2024“…</p><p><br></p><p dir="ltr">The bank is currently very under-leveraged: Tier-1 equity / RWA is 21% (vs. minimum 8% regulatory requirement)</p><p><br></p><p dir="ltr">Between the low leverage and the very low level of charge-offs and delinquencies, I view Ponce as an extremely safe bank to invest in.…”
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14187
Data Sheet 2_Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer.zip
Published 2025“…</p>Results<p>Clinical analysis revealed a disease control rate (DCR) of 71.43% for anlotinib monotherapy, which improved to 100% when combined with aPD-L1/aPD-1. In PBMC-PDX models, treatment evaluation showed that anlotinib decreased tumor volume, an effect further enhanced by its combination with aPD-L1. scRNA-seq analysis demonstrated that anlotinib reduced the proportions of myofibroblastic cancer-associated fibroblasts and ESM1<sup>+</sup> endothelial cells, resulting in decreased angiogenesis. …”
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14188
Data Sheet 7_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14189
Data Sheet 3_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14190
Data Sheet 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14191
Data Sheet 4_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14192
Data Sheet 5_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14193
Supplementary file 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.pdf
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14194
Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14195
Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14196
Data Sheet 8_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”
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14197
Image 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.tif
Published 2025“…In the dose-response meta-analysis, the prevalence of hypertension increased by 24% with every 1 ng/ml increase in GDF-15 (OR 1.24, 95% CI 1.16–1.33, P < 0.001). …”
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14198
Supplementary Material for: Long-Term Effects of Cognitive Behavioral Therapy on Sickness Absence and Cognitive Functioning in Patients with Stress-Related Disorders: Secondary Res...
Published 2025“…Results CBT and GHP had comparable effects on SA and cognitive functioning with no significant between-group effects (all p > .05). Analyzing effects across the entire sample, the number of SA days among those with any SA did not significantly change (p = .946) but the likelihood of having any SA decreased significantly by the 1YFU (OR = .92, 95% CI [.87, .96], p < .001). …”
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14199
Table 4_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx
Published 2025“…In the dose-response meta-analysis, the prevalence of hypertension increased by 24% with every 1 ng/ml increase in GDF-15 (OR 1.24, 95% CI 1.16–1.33, P < 0.001). …”
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14200
Table 3_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx
Published 2025“…In the dose-response meta-analysis, the prevalence of hypertension increased by 24% with every 1 ng/ml increase in GDF-15 (OR 1.24, 95% CI 1.16–1.33, P < 0.001). …”