Data Sheet 2_Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer.zip by Hongwei Lan (18849035)

“…Background<p>High-grade serous ovarian cancer (HGSOC) poses significant treatment challenges due to frequent recurrence and resistance to conventional therapies. …”

Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p... by Guoliang Gao (2910503)

“…According to the APC model, the worldwide incidence of hypertensive heart disease is expected to increase from 2022 to 2046, with further decreases in deaths and DALYs.</p>Conclusions<p>This study systematically reveals the increasing trend in the incidence of hypertensive heart disease globally between 1990 and 2021 and confirms the significant impact of sex and socioeconomic development level on its burden. …”

Analyzing the global burden of 11 subtypes of congenital birth defects: trends, sociodemographic correlates, and outcomes from 1990 to 2021 by Enhui Yang (11844002)

“…</p> <p>The study underscores the global impact of CBDs on child health, pointing to significant regional disparities linked to socioeconomic factors. …”

DataSheet1_An observational study of lower limb muscle imbalance assessment and gait analysis of badminton players.docx by Ping Huang (30439)

“…Purpose<p>The imbalance of muscle strength indicators has a negative impact on players. Lower limb muscle imbalance can cause gait abnormalities and increase the risk of muscle injury or decreased performance in significantly asymmetrical situations. …”

Table 1_Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.xlsx by Di Lian (11639675)

“…Introduction<p>Childhood asthma (CA) is a common chronic respiratory condition that significantly impacts the respiratory function and quality of life of affected children. …”

Table 6_Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.xlsx by Di Lian (11639675)

“…Introduction<p>Childhood asthma (CA) is a common chronic respiratory condition that significantly impacts the respiratory function and quality of life of affected children. …”

Table 5_Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.xlsx by Di Lian (11639675)

“…Introduction<p>Childhood asthma (CA) is a common chronic respiratory condition that significantly impacts the respiratory function and quality of life of affected children. …”

Table 3_Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.xlsx by Di Lian (11639675)

“…Introduction<p>Childhood asthma (CA) is a common chronic respiratory condition that significantly impacts the respiratory function and quality of life of affected children. …”

Table 4_Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.xlsx by Di Lian (11639675)

“…Introduction<p>Childhood asthma (CA) is a common chronic respiratory condition that significantly impacts the respiratory function and quality of life of affected children. …”

Table 2_Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.xlsx by Di Lian (11639675)

“…Introduction<p>Childhood asthma (CA) is a common chronic respiratory condition that significantly impacts the respiratory function and quality of life of affected children. …”

Image4_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Image 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.tif by Man Zhao (314232)

“…Treatment with MitoTEMPO after BNIP3 silencing further decreases the expression of NLRP1, while overexpression of NLRP1 nullifies the impact of BNIP3 knockdown. …”

Data Sheet 4_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”

Table 3_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc by Meizhi Liu (21898892)

“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”

Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Supplementary file 1_Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms.docx by Safiya Al Yazeedi (22075034)

“…<p>Mechanical strain plays a significant role in lung pathophysiology. Current two-dimensional (2D) in vitro models fail to capture the lung's dynamic mechanical environment. …”

Table 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx by Ilmari Pyykkö (2855153)

“…Purpose<p>This retrospective study aimed to analyze the symptom profile of Meniere's disease (MD) patients, particularly focusing on the cessation of episodic vertigo and the disease's longitudinal course and the impact of major symptoms on quality of life (QoL).…”

Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf by Man Zhao (314232)

“…Treatment with MitoTEMPO after BNIP3 silencing further decreases the expression of NLRP1, while overexpression of NLRP1 nullifies the impact of BNIP3 knockdown. …”

Table1_Body composition and perceived stress levels in transgender individuals after one year of gender affirming hormone therapy.docx by Chiara Ceolin (19553155)

“…Introduction<p>Higher stress levels are linked to increased body fat and decreased bone density, effects that can be exacerbated by lifestyle choices. …”

Supplementary file 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”