DataSheet4_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …"

DataSheet5_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …"

DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …"

DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …"

DataSheet2_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …"

Presentation 1_Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study.pdf حسب Brittany McFeeley (21104825)

"…Study 1.0 participants indicated a decrease in cognitive activities since the start of COVID-19 restrictions, whereas those in Study 2.0 reported an increase in cognitive activities.…"

HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2 حسب Kejian Zhou (22557101)

"…</p> <p>Fourteen days post-MCAO, Col003 treatment significantly decreased cerebral infarct volume and enhanced neurological function scores in rats. …"

Supplementary Material for: m6A eraser FTO promotes ATF3 expression impairing podocyte autophagy in diabetic nephropathy حسب figshare admin karger (2628495)

"…Diabetic nephropathy (DN) is characterized by podocyte injury and proteinuria, in which impaired autophagy is a key pathological contributor. …"

Data Sheet 1_Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survival.docx حسب Yanlin Wang (110566)

"…Interestingly, although the downregulation of the PI3K/AKT signaling pathway did not reach statistical significance, this vital pro-survival axis may still contribute to Treg impairment in pSS.…"

Image 2_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif حسب Viana Q. Pham (22081163)

"…<p>Effective communication between the brain and peripheral tissues is crucial for homeostasis and health, and its impairment is a defining feature of aging. Circumventricular organs, characterized by the presence of fenestrated capillaries and absence of a blood–brain barrier (BBB), play a crucial role in controlling substance exchange between the brain and the blood. …"

Image 1_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif حسب Viana Q. Pham (22081163)

"…<p>Effective communication between the brain and peripheral tissues is crucial for homeostasis and health, and its impairment is a defining feature of aging. Circumventricular organs, characterized by the presence of fenestrated capillaries and absence of a blood–brain barrier (BBB), play a crucial role in controlling substance exchange between the brain and the blood. …"

Data Sheet 1_Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.docx حسب Rui Sun (177521)

"…Tcirg1 deficiency in knockout mice delayed OA progression, as evidenced by reduced cartilage damage, improved subchondral bone mass, and decreased osteoclast activity. In vitro, Tcirg1 expression increased during osteoclast differentiation, and its knockdown inhibited osteoclast fusion and bone resorption by impairing lysosome acidification and peripheral accumulation.…"

The minimal anonymized data set. حسب Zufan Alamrie Asmare (16474982)

"…Therefore, improvement of post-operative visual outcome through decreasing intra-operative complications, managing post-operative complications, and investing in specialized training and equipment for ophthalmic surgeons are pivotal and need significant emphasis.…"

GnRH antagonist impairs the process of embryo implantation by inhibiting motility of endometrial stromal cells through reducing c-kit expression حسب Jun Tan (46388)

"…</i> 56.1%, <i>p</i> < .001) in the GnRH-ant group were significantly decreased. Contrarily, the rate of early miscarriage in the GnRH-ant group (13.95% <i>vs.…"

Supplementary file 1_Resting-state EEG alterations and cognitive impairment in atrial fibrillation: insights into neural biomarkers and functional connectivity.docx حسب Min-qiang Bao (21570074)

"…</p>Results<p>AF patients had significantly lower MoCA scores. PSD analysis showed increased δ and θ and decreased α and β activity. …"

Table_2_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx حسب Rui Zhu (305217)

Table_1_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx حسب Rui Zhu (305217)

Source data for Fig 2. حسب Qi Xu (134661)

"…Our findings demonstrated that hv<i>Kp</i> infection led to a decrease in lymphocytes (lymphopenia), attributed to impaired proliferation and apoptosis. …"

Source data for lung metabolomics. حسب Qi Xu (134661)

"…Our findings demonstrated that hv<i>Kp</i> infection led to a decrease in lymphocytes (lymphopenia), attributed to impaired proliferation and apoptosis. …"

Source data for Fig 5. حسب Qi Xu (134661)

"…Our findings demonstrated that hv<i>Kp</i> infection led to a decrease in lymphocytes (lymphopenia), attributed to impaired proliferation and apoptosis. …"