بدائل البحث:
significant impairment » significant improvement (توسيع البحث), significant improvements (توسيع البحث), significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant impairment » significant improvement (توسيع البحث), significant improvements (توسيع البحث), significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
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1041
Image 1_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.tiff
منشور في 2025"…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…"
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1042
Functional assays of neurotoxicity testing of α-terpineol in Wistar rats
منشور في 2025"…The research found that exposure to α- terpineol led to several adverse effects, such as reduced body weight, impaired motor coordination, and significant declines in sperm parameters and testosterone levels. …"
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1043
Supplementary Material for: Fibrillin-1 deficiency perturbs aortic cholinergic relaxation and adrenergic contraction in a mouse model of early onset progressively severe Marfan syn...
منشور في 2025"…Results: Isometric force measurements of aortic rings from 16-day-old male Fbn1mgR/mgR mice revealed a significant reduction in acetylcholine (ACh)-induced relaxation and increased phenylephrine (PE)-promoted contractility, associated with abnormally low eNOSSer1177 phosphorylation, decreased NO production and augmented superoxide levels. …"
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1044
Data Sheet 1_Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice.zip
منشور في 2025"…WB showed that P62 was significantly increased and RILP was significantly decreased in diabetic mice subjected to I/RI compared to healthy mice. …"
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1045
qorA associated data
منشور في 2025"…Notably, the <i>qorA</i> mutant exhibited impaired survival against neutrophil killing as well as reduced viability in human blood, plasma, and during mouse bloodstream infections, along with a significant decline in its anti-phagocytic capability. …"
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1046
Data Sheet 1_The C-terminal regions of the GLP-1 and GIP receptors are not the key determinants of their differential arrestin recruitment but modulate the rate of receptor endocyt...
منشور في 2025"…The reciprocal substitution significantly (P < 0.005) decreased internalization rate.…"
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1047
Supplementary file 1_Mechanism of soil microbial community degradation under long-term tomato monoculture in greenhouse.docx
منشور في 2025"…<p>Tomato (Solanum lycopersicum L.), an economically significant crop, is frequently cultivated in greenhouses under continuous monoculture systems. …"
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1048
Table 1_Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study.docx
منشور في 2025"…The prevalence of fatigue on admission was high (84.6%) and decreased significantly by discharge (77.4%), with a mild effect size. …"
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1049
Table 1_Effects of eculizumab and rituximab on visual function, motor function and social quality in patients with NMOSD: a comparative study.docx
منشور في 2025"…</p>Conclusion<p>NMOSD significantly impairs visual, motor, and social functions. …"
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1050
Table 2_Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study.docx
منشور في 2025"…The prevalence of fatigue on admission was high (84.6%) and decreased significantly by discharge (77.4%), with a mild effect size. …"
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1051
Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes...
منشور في 2025"…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …"
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1052
Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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1053
Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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1054
Table 5_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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1055
Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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1056
Table 2_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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1057
Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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1058
Table 1_Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases.docx
منشور في 2024"…<p>Retinal pathologies are major causes of vision impairment and blindness in humans, and inherited retinal diseases (IRDs), such as retinitis pigmentosa, Leber congenital amaurosis, and Stargardt disease, greatly contribute to this problem. …"
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1059
Table 1_Alterations in gut–kidney axis indicators and TMAO-related biomarkers in elderly patients with hypertensive nephropathy.xlsx
منشور في 2025"…</p>Results<p>The chronic kidney disease group exhibited elevated serum urea and creatinine and reduced eGFR, along with increased levels of KIM-1, NGAL, IL-18, TNF-α, IL-6, NF-κB, and FMO3. Urinary TMAO was significantly decreased in both hypertensive groups, while serum TMAO remained unchanged. …"
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1060
Supplementary file 1_Altered microstate C and D dynamics in high social anxiety: a resting-state EEG study.docx
منشور في 2025"…</p>Results<p>The high social anxiety group exhibited significantly increased duration and coverage of microstate C (associated with processing personally significant information and self-reflection) and decreased duration and coverage of microstate D (associated with executive functioning). …"